GIT Flashcards

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1
Q
1. Absorption of fat is defective when
destroyed by disease or resection of
a. Duodenum
b. Jejunum
c. Ileum
d. All of the above
A

c. Ileum

Lipolysis is completed in the duodenum and
jejunum by pancreatic lipase, which is
inactivated by a pH <7.0. (19th ed., p1935)

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2
Q
  1. Similar bet. GI TB & Crohn’s. EXCEPT.
    A. Caseating granuloma
    B. Lymph node involvement
    C. Fistula
A

A. Caseating granulomaThe earliest lesions are aphthoid ulcerations
and focal crypt abscesses with loose
aggregations of macrophages, which form
noncaseating granulomas in all layers of the
bowel wall (19th ed., p1952)

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3
Q
4. Malabsorption can be expected after
Bilroth II operation because
A. part of the pancreas is resected
B. Mucosa of small bowel is destroyed
C. Length of small bowel is reduced
D. Stasis at the afferent loop
A

D. Stasis at the afferent loop
Although rarely seen today as a result of the
decrease in the performance of Billroth II
anastomosis, two types of afferent loop
syndrome can occur in patients who have
undergone this type of partial gastric
resection. (19th ed., p1926)

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4
Q
  1. Racecadotril anti-diarrheal mechanism?
A
Racecadotril increases the availability of
endogenous opioids (enkephalins) by
inhibiting the membrane-bound
enkephalinase. The enkephalins in turn
mediate their effect through δ receptor
activation that induces a selective increase
in Cl absorption by inhibiting adenylate
cyclase.
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5
Q
  1. True of osmotic diarrhea –
A

Fasting lessens

symptoms

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6
Q
11. Postulated mechanism of how dietary
fiber can decrease the risk of colon CA
except
a. Dilute carcinogens
b. Decrease secondary bile acids
c. Increase colonic pH
d. ---
A

a. Dilute carcinogens

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7
Q
  1. Risk factor for increase colorectal CA
    a. Advanced age
    b. Aspirin
    c. IBS
    d. Polyps
A

d. Polyps

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8
Q
  1. Bad prognostic factor for Recurence of
    colonic ca after surgery
    A. Bleeding
    B. Adhesion to other organ
A

B. Adhesion to other organ

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9
Q
15. Trait of colonic poly with higher
malignancy
A. ---
b. 0.5 size
c. Pedinucleated
D. Villous polyp
A

D. Villous polyp

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10
Q
16. IBD occurs because
A. There is a predominance of pro
inflammatory cytokines
B. Mucosal system is normally reactive to
luminal contents
C. Intestinal mucosal cells treat as
commensals
D. AOTA
A

D. AOTA

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11
Q
  1. Main antibody in ulcerative colitis –
A

Perinuclear antineutrophil cytoplasmic

antibodies (pANCAs)

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12
Q
20. Expected in patients with IBD except
A. Hypoalbuminemia
B. Leukocytosis
C. Decreased ESR
D. Decreased hemoglobin
A

C. Decreased ESR

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13
Q
23. True of GITB
A. Far advanced TB on Xray predicts
presence of extrapulmonary TB
B. Current incidence is on the rise due to
AIDS
C. Non-caseating granuloma
D. Primarily treated surgically
A

B. Current incidence is on the rise due to

AIDS

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14
Q
24. Expected in patients with IBD except
A. Hypoalbuminemia
B. Leukocytosis
C. Decreased ESR
D. Decreased hemoglobin
A

C. Decreased ESR

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15
Q
27. Risk factor for bleeding diverticula
except:
a. Young age
b. NSAIDs
c. Hypertension
A

a. Young age

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16
Q
32. What happens after the first 12 hrs of
intestinal obstruction?
a. Increased reabsorption of water
b. Increased secretion of water
c. Decreased reabsorption of water
d. Decreased secretion of water
A

c. Decreased reabsorption of water

17
Q
33. Pain of mechanical intestinal obstruction
A. Crescendo-decrescendo - 
b. Continuous, non-progressing
c. Progressing rapidly
d. Sudden onset
A

A. Crescendo-decrescendo -Intestinal
obstruction due to mechanical factors can
be differentiated from pancreatitis by the
history of crescendo-decrescendo pain,
findings on abdominal examination, and CT
of the abdomen showing changes
characteristic of mechanical obstruction.

18
Q
38. Definite pathophysiology mechanism of
IBS
A. Altered intestinal motility
B. Visceral hypersensitivity
C. Abnormal gas expulsion and proportion
D. None
A

A. Altered intestinal motility

B. Visceral hypersensitivity

19
Q
  1. Management for IBS—constipation
    a. Loperamide
    b. SSRI
    c. TCA
    d. Serotonin antagonist
A

b. SSRI

20
Q
41. Most common cause of mechanical
LARGE intestinal obstruction.
A. Neoplastic
B. Adhesions
C. Hernia
D. Volvulus
A

A. Neoplastic

21
Q
42. Trait of colonic poly with higher
malignancy
A. B. 0.5 size
C. Pedinculated
D. Villous Polyp
A

D. Villous Polyp

22
Q
  1. To differentiate between E. hystolitica
    and other morphologically similar organisms,
    the following tests have diagnostic value
    except:
    A. PCR
    B. Serum antibodies to E. hystolitica
    C. ELISA for binding lectins
    D. Blood culture
A

D. Blood culture

23
Q
47. Treatment of hepatic amebic abscess
A. Iodoquinol
B. ---
C. Metronidazole
D. Poronomycin
A

C. Metronidazole

24
Q
  1. Not used in Pseudomembranous Colitis
    a. Aminoglycosides
    b. —
    c. Cyclophosphamide
    d. Vancomycin
A

c. Cyclophosphamide

25
Q
49. Difference between ulcerative colitis
and chron’s
A. pANCA
B. Caseating granuloma
C. Lymph node involvement
D. Fistula
A

A. pANCA

26
Q
50. Causes of adynamic ileus except
A. Heavy metal poisoning
B. Pancreatitis
C. MI
D. ---
A

A. Heavy metal poisoning

27
Q

**Polyposis with brain tumor
A. FAP
B. Turcot’s
C. Peutz-Jagger

A

B. Turcot’s