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GIT AND ENDO > ENDO RECALLS > Flashcards

ENDO RECALLS Flashcards

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Git Commands flashcards
1
Q

25 y/o female for evaluation, the patient have slow growing thyroid gland for 3 years, complained only nervousness and occasional palpitation, physical exam show BP 120/70, CR 70 beats per minute, thyroid gland is diffusely enlarged. no bruits, fine tremor and normal reflexia.. serum t4, t3 and tsh were normal.. what would likely be the diagnosis. a. simple goiter b. subclinical hypothyroidism

c. subclinical hypothyroidism
d. sick euthyroid syndrome

A

a. simple goiter

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2
Q 
Drugs not used for Hyperthyroidism EXCEPT: 
A. Methimazole 
B. Carbimazole 
C. PTU 
D. Aspirin
A

D. Aspirin

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3
Q

Specific action of Sulfonylureas: -

A

Increase insulin secretion from PPAR cells

Attach to Na-K ATPase channels  close
the potassium channels  calcium fluxes
in  result in release of insulin granules
from the beta cells

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4
Q

A diabetic patient comes to you with a total cholesterol of 220mg/dL and LDL of 150mg/dL. What is the recommended management?

a. Diet & exercise
b. Pharmacological treatment
c. Both a & b
d. Repeat evaluation after 2 months of behavior modification

A

BOTH

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5
Q 
Sheehans syndrome
a. Prolactin
b. GH
c. Acth
d.
A

all of the above

Thyroid-stimulating hormone (TSH) 
Luteinizing hormone (LH) w
Follicle-stimulating hormone (FSH) 
Growth hormone (GH) 
Adrenocorticotropic hormone (ACTH) 
Prolactin stimulates milk production.
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6
Q

Long acting, peakless insulin: - Glulisine -
Lispro -
Aspart -
Detemir

A

Detemir

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7
Q

Propylthiouracil action in hyperthyroidism:

a. Blocking the organification and coupling process
b. Inhibiting trapping and organification
c. Blocking proteolysis and
d. Competrive binding to carrier protein

A

a. Blocking the organification and coupling process

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8
Q

Apoprotein that is related to atherosclerotic

A

APOLIPOPROTEIN B

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9
Q

Compute for the Anion Gap
Na- 135 cl- 105 hco3- 16 Na-(cl+hco3) 0

na-(hco3+cl)
135-121
A. 10
 B. 14 
C. 18 
D. 16
A

B. 14

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10
Q

40 yr old executive. ldl 150mg/dl family history of dm hpn paternal side. non smoker non alcoholic a. diet exercise

b. pharmacologic tx
c. a & b
d. reassure..

A

c

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11
Q 
25y/o female, bmi 25kg/m2. Classified as 
A. Normal  bmi 
B. Overweight 
C. Obese 
D. None of the above
A

OVERWEIGHT

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12
Q

Action of sulfonylurea
Increase insuline sensitivity Decrease glucan
Increase insulin release by acting on PPAR Increase insulin by closing ATP

A

Increase insulin release by acting on PPAR

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13
Q 
Abnormal low dose and high dose dexamethasone 
A. Cushing disease 
B. Adrenal cushing
 C. EctopicACTH
D.
A

B. Adrenal cushing

In a subject with a normal hypothalamic–pituitary–adrenal (HPA) axis, a supraphysiological dose of dexamethasone can inhibit ACTH secretion by the pituitary leading to drop in cortisol level in serum, urine and saliva; such inhibition does not occur in patients with Cushing syndromE

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14
Q

Peakless” insulin: A. Lispro B. Aspart C. Detemir D. Glusine

A

GLARGINE

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15
Q

Which following drug can inhibit the t4 to t3 conversion in peripheral tissue A. Methimazole B. Carbimazole C. Strumazole D. PTU

A

D. PTU

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16
Q

Most common cause of cushing’s syndrome
Cushings dse.
Adrenal adenoma
Ectopic acth

A

Adrenal adenoma

17
Q

Not Consistent in the diagnosis of type 1 DM

A

ASD

18
Q

Moa of propylthiouracil?

A

TPO

X ORGANIFICATION AND COUPLING

19
Q

BMI compute 160 lbs. 5 ft 4 inches ht.

A

27.4

704X LBS/ IN 2

20
Q

Thyrotoxic manifestation except A. Constipation***
B. Palpitation
C. Tremors
D. Sweats

A

A. Constipation***

21
Q

Evaluation of graves’ disease: -

A

High T4, Low TSH

22
Q

Cannot uptake radioiodine

A

Options: Graves, adenoma, etc.

23
Q

Patient with amenorrhea galactorhea, management? Treatment?
Craniotomy
Transphenoidal

A

Transphenoidal

In males, PRL attenuates LH secretion, leading to low testosterone levels, diminished libido & diminished sexual potency, oligospermia & lowered ejaculate volume up to 30% may have galactorrhea
In women, hyperprolactinemia leads to loss of pulsatile LH secretion, blunting of the LH peak, hypoestrogenism & anovulation, oligomenorrhea & amenorrhea, vaginal dryness, dyspareunia, loss of libido & infertility

GIT AND ENDO (4 decks)

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