G.I.t Flashcards

1
Q

Barette oesophagus

A

Squamous cell to columnar cell

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2
Q

Itching,pruritis,skin excoriation middle age,in 40’s,women,elevated ALP,Sjogren Syndrome,Antimitochondrial antibodies positive( HALLMARK)

A

Primary biliary cirrhosis

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3
Q

Elderly
Smoker
Dysphagia difficulty swallowing
Weight loss

A

Oesophageal carcinoma

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4
Q

Right hemiparesis
Absent gag reflex
Strike unit
Dysphagia

A

Dysphagia less than 4 weeks -nasogastric tube.
Dysphagia is more than 4 weeks
-percutaneous endoscopic gastrostomy.

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5
Q

Large villous adenoma in sigmoid colon
Stools voluminous and foul smelling

A

Hypokalemia

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6
Q

Diarrhoea 6 Months/mild diarrhea 6weeks.
Bloating post meals
Flatulence post meals
No weight loss
No abdominal pain or intermittent abdominal pain
Type 1 DM*

A

Screen coeliac disease
TtG test
Serum Tissue Transglutaminase Antibody IgA
tTg-IgA
Positive then endoscopy and biopsy

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7
Q

Diarrhoea(6 month)
Bloating post meals
Flatulence post meals
No weight loss
No abdominal pain

A

Screen coeliac disease
Tissue Transglutaminase Antibody (TTG test)

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8
Q

Severe Pain abdomen
Blood stool +
Systemic signs inflammation
Fever
weight loss

A

Inflammatory Bowel Disease
Faecal calprotectin

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9
Q

Change in bowel habits

A

Ruling out colorectal cancer
Faecal immunochemical test (FIT)

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10
Q

Hb
WBC
Crp
Platlet

A

130-180
4-11
<10
150-400

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11
Q

Right abdomen tenderness
Late teens,twenties
Active inflammation (plt+,CRP+)
Faecal calprotectin positive

A

Colonoscopy (direct visualization ileum)
Crohn’s disease

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12
Q

Epigastric pain few hours
Bouts diarrhoea few hours
Nauseous
No vomiting

A

Gastroenteritis (norovirus)
Isolate until diarrhea resolves

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13
Q

Pathology report
Large Iron pigment within hepatocytes
Abnormal liver function test
Triad
Diabetes
Hepatomegaly
Bronze pigmentation

A

Hemochromatosis
Hereditary hemochromatosis -autosomal recessive genetic disease.
(Increased intestinal absorption iron)

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14
Q

Iron in kuppfer cells

A

Hemosiderosis

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15
Q

Hemochromatosis investigation

A

Ferritin raised >1000
Transferrin saturation raised> 45%
Genetic testing
Liver biopsy

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16
Q

Liver firm ,span 10cm
Skin pigmentation
Heart murmur( restrictive cardiomyopathy)

A

Heamochromatosis
Hepatoma(hepatocellular carcinomas)

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17
Q

Palpable mass right iliac fossa
Bloody diarrhoea
Weight loss
H/E
Granulomas

A

Crohn’s disease

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18
Q

Palpable mass right iliac fossa
Bloody diarrhoea
Weight loss
H/E
Granulomas

A

Crohn’s disease

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19
Q

Upper gastrointestinal bleed
Urgent Endoscopy (to find out site bleed)

A

Melena- black tarry stools.
Anemia .
Haemoglobin ,72(130-18)
Haematocrit 21(40-50)
Hemodynamically unstable .

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20
Q

Upper gi bleed

A

Inj adrenaline
Application clips
Cauterisation to stop bleeding

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21
Q

Intervention for upper gi bleed

A

1.resuscitation with fluids +/- packed red cells
2. Endoscopy

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22
Q

Investigation hiatus hernia

A

Endoscopy
Barium swallow
Oesophageal manometry
Treatment
Proton pump inhibitors
Laparoscopic fundoplication

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23
Q

Symptoms hiatus hernia

A

Retrosternal burning sensation lying down or bending
Asymptomatic

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24
Q

Bloody diarrhoea
Non bloody diarrhoea
Abdominal mass RT iliac fossa
Any part gi tract from anus to rectum
Histology - increased goblet cells,granulomas
Weight loss prominent
Endoscopy -transmural skip lesions
Cobble stone appearance.
Rx- corticosteroids - prednisolone

A

Crohn’s disease

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25
Q

Oesophageal cancer co dysphagia palliative care

A

Oesophageal stenting

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26
Q

Stroke difficulty swallowing
risk aspirations pneumonia
Long term feeding

A

Percutaneous endoscopic gastrostomy (peg)

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27
Q

Chest pain (retrosternal)
Interscapular pain
Subcutaneous emphysema
Retching
Vomitting
Fever
Tachycardia
Post gi endoscopy

A

Oesophageal rupture cause mediastinitis.
Macklers triad
1.Chest pain
2.Vomitting
3.Emphysema

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28
Q

Urgent Endoscopy

A

Dysphagia to rule out oesophageal and stomach cancer
55yrs above- wt loss,upper gi pain,reflux, dyspepsia
H/o ibuprofen ,tender abdomen over 55yrs

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29
Q

Routine endoscopy

A

Refractory dyspepsia (4 weeks ppi)
Hbpylori eradication regimen

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30
Q

Sudden onset dysphagia
Drooling
Regurgitation
No signs respiratory distress
Vitals stable
Next investigation

A

Oesophagogastroduodenoscopy
OGD

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31
Q

Re-testing helicobacter pylori

A

Carbon -13 urea breath test (ppi are stopped 2 weeks back,28 day break after treatment)
not available
Stool antigen test

32
Q

Children
Abdominal pain rt
iliac fossa
Diarrhoea
Weight loss

A

Crohn’s disease

33
Q

Type 2 DM
Arthropathy joint ache
Increase breast size gynaecomastia
Deep tan colour skin
Increasingly fatigue

A

Hemochromatosis

34
Q

Cirrhotic man
Gradually worsening Abdominal swelling
Fever ,absent bowel sounds
Examination -rebound tenderness, shifting dullness
Elevated temp, tachycardia
Most appropriate investigation?

A

(Cirrhosis-Ascites-bacterial peritonitis -)
Neutrophil count more than 250
Rx- antibiotics

35
Q

Bloody diarrhoea more common
Abdominal pain left quadrant
Histology -decreased goblet cells,granulomas infrequent,primary sclerosing cholangitis more common
Barium enema-loss haustrations,drain pipe colon

A

Ulcerative collitis

36
Q

Lethargy
Dull worsening pain right hypochondrium
Histology of liver Biopsy-adenocarcinoma;TTF -Primary pulmonary tumour
Most likely route metastases

A

Hematogenous

37
Q

Epigastric pain
Nausea
Vomitting @ 35 weeks gestation ++
Preeclampsia
Deranged liver function test ++
Low platelets ++
Low serum glucose ++
Raised serum ammonia++

A

Acute fatty liver of pregnancy

38
Q

Difficulty Swallowing solids-dysphagia
Loss weight
Heart burn
Acidic taste
Elderly

A

(GORD - oesophageal cancer) most appropriate investigation
Upper GI endoscopy

39
Q

Severe epigastric pain
Radiate to back
Relieved sitting forward*
Nauseous, vomiting twice
Tender epigastric
Appropriate investigation
One half glasses wine per day

A

Serum lipase sensitive (3*)
Dx-acute pancreatitis

40
Q

72 yrs old women
Tender mass left side abdomen iliac fossa
Guarding+

A

(Diverticulitis)
Diverticular abscess

41
Q

Intermittent dysphagia +
6 months
great relief after regurgitation+
Recurrent respiratory tract infection +
Night time coughing fits

A

Achalasia
Loss ability to relax (close) lower oesophageal sphincter.
1.endoscopy
2.manometry(gold standard)
3.barium swallow.

42
Q

Severe diarrhea
Opens her bowels (8)
Hereditary factor colorectal carcinoma
Colicky abdominal pain
Ulcerative collitis on sulfalazine
Pale
Tender abdomen no mass

A

Severe exacerbation ulcerative collitis
Intravenous hydrocortisone.

43
Q

Difficulty swallowing foods
Barium meal - dilatation oesophagus narrowing lower end (birds beak )

44
Q

Impacted faeces for 1 week

A

Fast acting laxative
Phosphate enema(2-5min)

45
Q

Stool blood and mucus
Abdominal pain
4-5 stools / day
Anca positive
As a negative

A

Mesalazine(mild to moderate ulcerative collitis

46
Q

Long standing heart burn, dysphagia (GORD)
HIATUS HERNIA

A

barrets oesophagus

47
Q

Long standing heart burn, dysphagia (GORD)
HIATUS HERNIA

A

barrets oesophagus

48
Q

Stinking stools
Frothy stools
Stearohea Ferritin low
Folate low
Weight loss
Bloating
Intermittent diarrhea (long term)

A

Coeliac disease
Tissue Transglutaminase antibodies (TTG,IgA)

49
Q

Head pancreas removed
Worsening Abdominal pain
Rigid abdomen
Pud (peptic ulcer disease)
BP -95/55
Pr -125

A

Erect chest x-ray and abdomen (Perforated peptic ulcer - air under diaphragm)

50
Q

Head pancreas removed
Worsening Abdominal pain
Rigid abdomen
Pud (peptic ulcer disease)
BP -95/55
Pr -125

A

Erect chest x-ray and abdomen (Perforated peptic ulcer - air under diaphragm)

51
Q

Long standing gastric reflux
Dysphagia - solid then soft food also
Chest pain
Barium meal- irregular narrowing

A

Oesophageal carcinoma

52
Q

Recurrent abdominal pain
Periumbilically
Associated Nausea,episodic headache
Interferes normal activity

A

Reassure
Rx abdominal migraine

53
Q

Severe upper Abdominal pain
Vomitted several times ,5 children
Female
Forties
Fair
Fertile
Fat

A

Cholecystitis( gallstones)

54
Q

Difficulty swallowing blood
One episode once every few days
Chest pain with dysphagia
Regurgitate food
Chest infection recurrence
No weight loss
Investigation?

55
Q

Crushing chest discomfort 1 HR
On drinking colddrink*

A

Oesophageal spasm

56
Q

Lump left supraventricular region
Loss appetite
Lost 10 kg

A

Gastric cancer
Lump -virchow ‘s node- trousers sign.

57
Q

Intermittent episodes sudden chest pain
Dysphagia
3 weeks ago
Crushing lower substernal

A

(Dx-Oesophageal spasm)
Gold standard - manometry

58
Q

RT. Upper quadrant pain
Jaundice
Well nourished man
No weight loss
Tenderness in RT. upper quadrant
Next investigation

A

Ultrasound

59
Q

Bloody diarrhoea
Bloody diarrhoea
Biopsy -colonic mucosa crypt abscesses

A

Ulcerative collitis

60
Q

Rash buttock
Recurrent chronic diarrhea
I’ll fitting clothes

A

Villous atrophy
(Rash - dermatitis herpetiformis)

61
Q

Bloating, abdominal pain worsened post meal,relieved by defecation

A

Irritable bowel syndrome

62
Q

Increasingly fatigue
Gastrectomy

A

Hypersegmented neutrophils
(Vitamin b 12 deficiency)

63
Q

Wt loss
Colonoscopy fistulas

A

Crohn’s ds

64
Q

Night rectal shooting pain
Pr is normal

A

Proctalgia fugac

65
Q

Charcot triad
fever
Right upper quadrant pain
Jaundice
Procedure retrograde cholangiopancreatography

A

Ascending cholangitis

66
Q

Pain relieves on leaning forward

A

Acute pancreatitis

67
Q

Tenesmus
Intermittent diarrhea
Chronic abdominal pain

A

Inflammatory bowel disease

68
Q

Intermittent dysphagia
Nocturnal cough
weight loss
Heart burn lying flat

69
Q

Acute severe collitid

A

Intravenous hydrocortisone

70
Q

Clindamycin - increases clostridium defficle infections

A

Oral vancomycin

71
Q

Right upper quadrant pain
On palpation right costal margin at midclavicular line,interruption of breathing (muphys sign)

A

Acute cholecystitis

72
Q

Blistering rash elbow- red raised patches ,blisters,severe itching.
Biopsy - shortening villi ( villous atrophy)
Low haemoglobin
Lymphocytosis

A

Rash - dermatitis herpetiformis
Coeliac disease

73
Q

Investigation coeliac disease
Symptoms
Intermittent diarrhea
Stearohea
Stinking stools
Bloating
Nausea
Vomiting
Fatigue
Weight loss
Iron ,bit B 12 Def,folate Def.

A

Tissue Transglutaminase antibodies TTG

74
Q

Jejunal / duodenal biopsy in coeliac disease

A

Villous atrophy
Crypt hyperplasia
Increase in intraepithelial lymphocytes

75
Q

Endoscopy
Chest pain
Shortness breath
Cxr-mediastinal widening
Epigastric pain radiating to interscapular

A

Mediastinitis (oesophageal perforation)

76
Q

Pain,bloating,change in bowel habits
Pain relieved defecation,

A

Tissue Transglutaminase antibody (coeliac ds)
Faecal calprotectin (inflammatory bowel ds
Fit sample(colon cancer 50yrs above)
Ca 125 ovarian cancer (women 50 yrs above)

77
Q

Low Hb,high MCV
Ileal resection

A

Vitamin b12 def