Gigantism

Question 1

cause

Answer 1

increased growth hormone secretion before adolescence

Question 2

Manifestations:

Answer 2

(1) increase rate of growth of all body
tissues (skeleton and soft tissues)
(2) increase growth of bones and height
of child may reach 8-9 feet (giant)
(3) Infantile gonads (hypogonadism)
why? due to pressure of tumor on
gonadotropic cells leading to
decrease secretion of GnTH
(4) The giant has hyperglycemia, and
May develop DM
(5) bitemporal heminopia. why?
Due to pressure of tumor
on optic chiasma