GI Week 2-4 Quiz Flashcards

1
Q

On the attached image which of the labels corresponds to the aponeurosis of the transversus abdominis muscle?

A. A
B. B
C. C

A

B. B

The anterolateral abdominal muscles have flattened tendons called aponeuroses.
These look white in contrast to the colour of the muscle fibre.
Apart from the order in which the muscles lie (superficial to deep) you can identify the muscles from the orientation of their fibres.
A is a tendinous intersection in the rectus abdominis muscle
B is the aponeurosis of the transversus abdominis muscle
C is the aponeurosis of internal oblique

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2
Q

Where in the GI tract will you find stratified squamous epithelia?

A. Proximal stomach
B. Terminal ileum
C. Proximal anal canal
D. Distal anal canal

A

D. Distal anal canal

Most of the gut is lined with simple columnar epithelium but the oesophagus and distal anus is lined with stratified squamous. Stratified squamous epithelium is good at resisting frictional forces and this helpful because contents of the gut in the oesophagus and distal anus are at their most solid (predigested in the oesophagus and desiccated in the anus).

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3
Q

At average flow rates the tonicity of saliva is best described as ……?

A. Hypotonic
B. Hypertonic
C. Isotonic

A

A. Hypotonic

When saliva is produced in the acinus of the salivary gland it is close to the tonicity of plasma (isotonic). However as it moves along the ducts of the salivary gland, the ductal cells modify the composition of saliva and there is a net removal of ions (Na, Cl) and the resulting solution is hypotonic.
As flow rates of saliva increase, the contact time the ductal cells have with the initially isotonic solution is less and less modification occurs. Therefore at higher flow rates saliva becomes less hypotonic (compared with lower flow rates).

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4
Q

What happens to the concentration of Bicarbonate ions (HCO3-) at higher flow rates of saliva?

A. Decrease
B. Increase
C. Stay the same

A

B. Increase

HCO3- ions are the exception in the production of saliva in that they actually increase at higher flow rates. HCO3- is secreted by the ductal cells in proportion to the flow rates.
This is different to the other ions in saliva, where a higher flow rate results in less movement across the ductal cells (less ductal modification).

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5
Q

Where in the GI tract are digestive enzymes first secreted?

A. Duodenum
B. Jejenum
C. Stomach
D. Oral cavity

A

D. Oral cavity

The oral cavity is the first environment in the GI tract where digestive enzymes are released (salivary amylase and lipase). Following that the stomach releases enzymes to break down protein and fat. The main producer of digestive enzymes is the pancreas which releases its enzymes into the duodenum via the major pancreatic duct.

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6
Q

The anterior boundary of the lesser saci s partially formed by the …..?

A. Anterior surface of the Pancreas
B. Posterior surface of stomach
C. Inferior surface of the Diaphragm

A

B. Posterior surface of stomach

The anterior boundary of the lesser sac is formed by the lesser omentum, the posterior surface of the stomach and even part of the greater omentum.
The diaphragm and pancreas (or at least the peritoneum covering the anterior surface of the pancreas) form part of the posterior boundary of the lesser sac.

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7
Q

The paracolic gutters are channels within the peritoneal cavity that connect the supracolic and infracolic compartments. Where do they lie?

A. Lateral to the mesentery of the small bowel
B. Between the rectum and the uterus
C. Lateral to the ascending and descending colon

A

C. Lateral to the ascending and descending colon

The paracolic gutters lie lateral to the ascending and descending colon (between the lateral aspect of the ascending and descending colon and the lateral abdominal wall).
The space between the rectum and the uterus (obviously only in females) is called the rectouterine pouch (pouch of Douglas).

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8
Q

What is the main reason a strangulated abdominal hernia requires urgent medical attention?

A. Patient experiencing extreme pain
B. Hernia is irreducible
C. Blood supply to hernia is compromised

A

C. Blood supply to hernia is compromised

A strangulated hernia is one where the blood supply to the contents of the hernia is compromised. This needs to be treated as an emergency otherwise the contents will undergo necrosis which could prove fatal for the patient.
This question was testing understanding of the term strangulated as opposed to the term incarcerated which is another way of saying the hernia is irreducible (stuck).

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9
Q

Where do the majority of digestive enzymes enter the gastro-intestinal tract?

Drop an answer pin by clicking on the image below.

A

Although there are some amylases and lipases in saliva, the majority of digestive enzymes are produced by the pancreas and released into the duodenum.

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10
Q

Classical appendicitis presents with vague peri-umbilical abdominal pain which some time later localises to the Right iliac fossa. Why does this pain eventually LOCALISE to the right iliac fossa?

A. Inflammation of visceral peritoneum enveloping the appendix
B. Inflammation of parietal peritoneum near the appendix
C. Rupture of appendix

A

B. Inflammation of parietal peritoneum near the appendix

The answer is inflammation of the parietal peritoneum near the appendix.
This question is related to how the different elements of the peritoneal cavity respond to noxious stimuli.
The peritoneal cavity is defined as the potential space between the visceral and parietal peritoneum. The visceral and parietal peritoneum develop slightly differently (although they form a continuous structure they develop along different embryological paths) with the visceral peritoneum not being able to localise pain and the parietal peritoneum being able to localise pain.
When the appendix initially becomes inflamed, the visceral peritoneum (that envelops it) is stimulated but cannot localise the pain. Being a midgut structure it refers this pain as a vague peri-umbilical pain (foregut structures refer to the epigastric area and hindgut to the supra-pubic area). However once the inflammation has progressed the parietal peritoneum in the region of the appendix can be stimulated and this will localise the pain. The pain is then felt more specifically in the right iliac fossa.

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11
Q

In the pharyngeal phase of swallowing, what structure helps prevent reflux of food into the naso-pharynx?

A. Epiglottis
B. Pharyngeal constrictors
C. Upper oesophageal sphincter
D. Soft palate
E. Vocal cords
A

D. Soft palate

The soft palate elevates to seal off the naso-pharynx. The pharyngeal constrictors effectively propel the food towards the oesophagus. The upper oesophageal sphincter prevents reflux of material from the oesophagus into the pharynx and the vocal cords adduct to protect the airway.

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12
Q

Indicate the internal oblique muscle on the attached image (which views the abdomen on its right side)

Drop an answer pin by clicking on the image below.

A

Internal oblique has fibres that pass superiorly and medially. You can also locate it because it lies directly underneath the external oblique (whose fibres run in a ‘hands in pockets’ direction).

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13
Q

Where in the gut wall is Meissner’s plexus found?

A. Mucosa
B. Submucosa
C. Muscularis propria
D. Serosa

A

B. Submucosa

Meissner’s plexus is also known as the submucosal plexus and is one of the two main plexus’ of the enteric nervous system. As its (other) name implies it lies in the submucosa. Auerbach’s plexus (myenteric plexus) is found in between the inner circular and outer longitudinal muscles of the muscularis propria.

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14
Q

During embryological development of the gut, which artery forms the axis of the midgut loop that herniates?

A. Coeliac trunk
B. Inferior mesenteric artery
C. Superior mesenteric artery

A

C. Superior mesenteric artery

The SMA forms the axis of the midgut loop that physiologically herniates during development. The SMA remains the arterial blood supply for the midgut derivatives (second part of the duodenum to 2/3 the length of the transverse colon)

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15
Q

Which of these is NOT a function of the stomach?

A. Protein absorption
B. Protein denaturing
C. Protein digestion

A

A. Protein absorption

The stomach releases HCl which helps to denature proteins and also releases pepsin (a protease enzyme) which begins the process of protein digestion. The stomach is not a site for much absorption, nutrients are absorbed mainly in the proximal small intestine.

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16
Q

Each label on the attached diagram is the location of an abdominal hernia.

Which label indicates a hernia that occurs below the inguinal ligament and is more common in females than in males?

A. A
B. B
C. C
D. D

A

D. D

Although not entirely clear on the diagram, the only label that is below the inguinal ligament is D. D is a femoral hernia and these are more common in females than in males because of the anatomy of the female pelvis. they are rare but because of the narrow femoral canal that they herniate through, incarceration and strangulation are not uncommon.

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17
Q

Each label on the attached diagram is the location of an abdominal hernia.

Which label indicates a hernia that affects young infants and usually spontaneously resolves in the first few years of life?

A. A
B. B
C. C
D. D

A

B. B

Label B is an umbilical hernia.
Due to the herniation of the midgut through the umbilical ring during embryological development, this area represents a potential weakness in the abdominal wall. Failure of closure of the umbilical ring allows these hernias to arise. The hernias are usually just observed as most spontaneously reduce within the first few years of life.

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18
Q

Concerning the autonomic nervous system in the gut.

Where do the parasympathetic PRE-GANGLIONIC fibres synapse in the gut?

A. Pre-vertebral ganglia
B. Sympathetic chain
C. Visceral wall

A

C. Visceral wall

The parasympathetic pre-ganglionic fibres synapse in the wall of the innervated viscera. There is then a very short post-ganglionic fibre which also sits within the wall of the viscera.

The sympathetic outflow in the gut passes through the sympathetic chain and then synapses in one of the pre-vertebral ganglia. Its post-ganglionic fibres are longer and extend to the walls of the viscera to innervate them.

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19
Q

What structure forms the floor of the inguinal canal?

A. Conjoint tendon
B. Inguinal ligament
C. Internal oblique
D. Transversalis fascia

A

B. Inguinal ligament

The floor of the inguinal ligament (canal?) is formed from the inguinal ligament
The posterior wall is formed from transversalis fascia and the conjoint tendon reinforces the medial aspect of the posterior wall. The roof is formed from arching fibres of internal oblique and the transverse abdominal muscle. The anterior wall is formed from the aponeurosis of external oblique.

20
Q

The term ‘cranio-sacral outflow’ relates to which part of the nerve supply to the gut?

A. Enteric nervous system
B. Parasympathetic nervous system
C. Sympathetic nervous system

A

B. Parasympathetic nervous system

The term cranio-sacral outflow relates to the parasympathetic nervous system. This is because it is comprised of the vagus nerve (CN 10) which leaves the brain stem (cranio bit) and some pelvic nerves which leave the sacral spine (sacral bit).

21
Q

What are the borders of Hesselbach’s triangle (the site for a direct inguinal hernia)?

A. Inguinal canal / inferior epigastric vessels / lateral border of the rectus abdominus muscles
B. Inguinal ligament / inferior epigastric vessels / lateral border of the rectus abdominus muscles
C. Inguinal ligament / inferior epigastric vessels / vertical line in the midpoint of abdominal wall

A

B. Inguinal ligament / inferior epigastric vessels / lateral border of the rectus abdominus muscles

The boundaries of Hesselbach’s triangle are the Inguinal ligament, inferior epigastric vessels & lateral border of the rectus abdominus muscles. This is important to know for inguinal hernia anatomy and being able to describe the difference between a direct and indirect inguinal hernia. A direct inguinal hernia will bulge through Hesselbach’s triangle as it is a relative weak point in the anterior abdominal wall.

22
Q

What path does a DIRECT inguinal hernia follow as it leaves the abdomen?

A. It passes below the inguinal ligament
B. It passes lateral to the inferior epigastric vessels
C. It passes through the deep inguinal ring
D. It passes through a weakness in Hesselbach’s triangle

A

D. It passes through a weakness in Hesselbach’s triangle

The best answer from above is that is passes through Hesselbachs triangle (please know the borders of this). An indirect inguinal hernia passes lateral to the inferior epigastric vessels (a direct hernia passes medial to them) and through the deep inguinal ring. A femoral hernia passes below the inguinal ligament, inguinal hernias (direct and indirect) pass above the inguinal ligament.

23
Q

Which of the following is NOT true for the pharyngeal phase of swallowing?

A. Involuntary
B. Soft palate seals off nasopharynx
C. Larynx depresses, opening epiglottis
D. Upper oesophageal sphincter opens

A

C. Larynx depresses, opening epiglottis

Pharyngeal phase (7.4-7.6)

  • Involuntary
  • Soft palate seals off nasopharynx
  • Pharyngeal constrictors push bolus downwards
  • Larynx elevates, closing epiglottis
  • Vocal cords adduct (protecting airway) and breathing temporarily ceases
  • Opening of the upper oesophageal sphincter

The larynx must elevate to close the epiglottis, otherwise the risk of food material entering the airway is increased.

24
Q

What type of hernia might be precipitated by a weakened conjont tendon?

A. Direct inguinal hernia
B. Indirect inguinal hernia
C. Femoral hernia
D. Umbilical hernia

A

A. Direct inguinal hernia

The conjoint tendon serves to reinforce the medial part of the posterior wall of the inguinal canal. It lies behind the superficial inguinal ring. This is the location a direct inguinal hernia can form and so if the conjoint tendon is weakened then a direct inguinal hernia is more likely.

25
Q

A femoral hernia protrudes through the femoral ring and down the femoral canal.

What forms the lateral border of the femoral ring?

A. Lacunar ligament
B. Femoral vein
C. Inguinal ligament
D. Femoral artery
E. Pectineal ligament
A

B. Femoral vein

Remember NAVEL. Nerve, Artery, Vein, Empty space, Lymphatics. This is the femoral region going from lateral to medial. The empty space is the femoral canal and at the top of the femoral canal is the femoral ring. The femoral ring is the initial defect a femoral hernia will pass through and so you may be asked about its borders. Laterally to the femoral ring is the femoral vein, medial the lacunar ligament, anterior the inguinal ligament and posteriorly the pectineal ligament.

26
Q

What is the location of the linea alba?

A. Horizontal between the umbilicus an the pubic symphysis
B. Vertical in the midline from xiphoid process to pubic symphysis
C. Vertical and lateral to the rectus abdominus muscles

A

B. Vertical in the midline from xiphoid process to pubic symphysis

The linea alba is a midline fascia structure that extends from the xiphoid sternum to the pubic symphysis and is the site for a midline laparotomy incision.
Vertical and lateral to the rectus abdominis muscles is termed the linea semilunaris which is often described as a curved line running lateral to the rectus muscles.
Horizontal between the umbilicus and the pubic symphysis is the arcuate line which is a transition point for the structure of the rectus sheath.

27
Q

Where in the gut is Vit B12 absorbed?

Drop an answer pin by clicking on the image below.

A

Vitamin B12 is absorbed in the terminal ileum, so any disease process (or resection) affecting the terminal ileum can result in reduced absorption of B12 (potentially leading to anaemia and neurological disorders).

28
Q

The anterolateral abdominal muscles are arranged in layers. Which of the following sequences is correct (superficial to deep)?

A. External oblique / transversus abdominis / internal oblique
B. Transversus abdominis / external oblique / internal oblique
C. External oblique / internal oblique / transversus abdominis

A

C. External oblique / internal oblique / transversus abdominis

These flat muscles are arranged with external oblique the most superficial (inferior & medial direction), internal oblique (superior & medial direction) and transversus abdominis the deepest muscle of this group (transverse fibre direction).

29
Q

During embryological development the entire gut tube is suspended by a dorsal mesentery.

Which part of the developing gut tube also has a ventral mesentery?

A. Foregut
B. Midgut
C. Hindgut

A

A. Foregut

The foregut has both a dorsal and ventral mesentery (remember venter means belly, so ventral mesentery attaches to anterior belly). The liver then develops within this ventral mesentery.

30
Q

What double fold of peritoneum connects the stomach to the liver?

A. Falciform ligament
B. Gastro-colic ligament
C. Lesser omentum

A

C. Lesser omentum

The lesser omentum is the double fold of peritoneum that connects the stomach to the liver.
The gastro-colic ligament connects the greater curve of the stomach to the transverse colon and the falciform ligament connects the liver to the anterior abdominal wall.

31
Q

Vague (midline) suprapubic abdominal pain could indicate a problem in which part of the GI tract?

A. Appendix
B. Terminal ileum
C. Sigmoid colon

A

C. Sigmoid colon

To answer this question you need to know what structures lie in which embryological division of the GI tract. the appendix and terminal ileum are midgut structures and the sigmoid colon is hindgut. Hindgut visceral pain is usually felt in the suprapubic area.

32
Q

A lady visits her GP complaining of a dry mouth and difficulty swallowing.

Name two of the three paired salivary glands (2x 1/2 marks)

A

Two from below for 1x mark

1) Parotid
2) Sublingual
3) Submandibular/Submaxilliary

33
Q

The Acinar cells of the salivary glands produce a fluid that is initially isotonic (with plasma), but the end product is a solution that is hypotonic.

Explain the process of producing hypotonic saliva (3x 1 marks).

A

Ductal modification

  • More ions reabsorbed from saliva than secreted into saliva
  • Ductal cells relatively impermeable to water
  • Overall effect is more ions removed from saliva than water = hypotonic
34
Q

What is the main neural control of saliva production? (1x mark)

A

Autonomic nerves/parasympathetic (stimulates majority) and sympathetic has some stimulatory effect.

35
Q

Briefly outline the main features and processes that occur during the pharyngeal phase of Swallowing (6x 1/2 marks)

A
  • Involuntary
  • Tongue against hard palate (food cannot re-enter mouth)
  • Soft palate elevated (seals of nasal cavity)
  • Longitudinal muscles shorten (pharynx widens to receive bolus)
  • Epiglottis closes
  • Bolus moves by constrictor muscles
  • Relaxation of the UOS
36
Q

The lady reports that she is also having problems swallowing solid foods (swallowing fluids is unaffected)

Describe another cause of dysphagia where swallowing solids is harder than swallowing liquids

A
  • Any physical obstruction from the oral cavity to the gastro-oesophageal junction
  • ie various cancers (usually squamous cell carcinoma or adenocarcinoma)
  • fibrous strictures
  • external compression from structures surrounding the oesophagus
37
Q

Describe a suitable investigation for Dysphagia to solid foods

A
  • Barium swallow
  • Oesophago-gastro-duodenoscopy (OGD)
  • Accept Videofluroscopy
  • CXR- for external compression
38
Q

Where in the abdomen might a patient complain of pain if there was a problem with their jejunum?

A. Epigastric area
B. Peri-umbilical area
C. Suprapubic area

A

B. Peri-umbilical area

To answer this question you need to know what embryological division the jejunum belongs to (mid-gut). You can then use the rule of thumb that foregut structure pain is felt in the epigastric area, midgut pain in the periumbilical area and hindgut pain in the suprapubic area. This relates to the fact that visceral afferent nerves (that conduct information relating to pain) follow the sympathetic supply to that section of the gut back to the spinal cord. Therefore the jejunum follows the lesser splanchnic nerve back to T10-11 spinal level. The brain interprets the pain coming from the T10-11 dermatomes, which correlates with the periumbilical area.

39
Q

Which of the following viscera has a blood supply derived from both the foregut and midgut?

A. Jejunum
B. Pancreas
C. Spleen
D. Stomach

A

B. Pancreas

Embryologically the pancreas develops on the junction of the foregut and midgut (as does the duodenum) and so has a dual blood supply.
The spleen and stomach are supplied by the foregut blood supply and the jejunum by the midgut blood supply.

40
Q

What section of the GI tract is the appendix located?

A. Caecum
B. Descending colon
C. Duodenum
D. Ileum
E. Jejunum
A

A. Caecum

The appendix is most commonly located on the caecum which is the start of the large intestine. The Caecum is a large bulge in the GI tract that follows on from the end of the ileum (called the terminal ileum).

41
Q

What is the major function of the Colon?

A. Digestion
B. Nutrient absorption
C. Water absorption

A

C. Water absorption

Water absorption is the most appropriate answer. However it is important to note that most of the water in the gut has already been absorbed by the small intestine and the colon simply removes the rest (almost all the rest). It does not play a major role in nutrient absorption.

42
Q

What section of the GI tract follows on from the descending colon?

A. Caecum
B. Duodenum
C. Jejunum
D. Ileum
E. Sigmoid colon
A

E. Sigmoid colon

The duodenum follows on from the stomach. The first part of the duodenum that joints to the stomach is called the duodenal bulb and is a common site for ulcers.

43
Q

An indirect inguinal hernia is a hernia that leaves the abdominal cavity and travels along the inguinal canal. Which of the following anatomical features is true for an indirect inguinal hernia?

A. Passes through Hesselbach’s triangle
B. Passes inferior to the inguinal ligament
C. Passes medial to the inferior epigastric vessels
D. Passes through the deep inguinal ring

A

D. Passes through the deep inguinal ring

An indirect inguinal hernia passes through the deep inguinal ring into the inguinal canal. If the processus vaginalis has failed to close then the hernia can pass through the inguinal canal out of the superficial inguinal ring and even into the scrotum.
A direct inguinal hernia passes medial to the inferior epigastric vessels which also happens to be the superolateral border of Hesselbach’s triangle (an area of potential weakness in the anterior abdominal wall).
In contrast an indirect inguinal hernia passes lateral to the inferior epigastric vessels.
A femoral hernia passes inferior to the inguinal ligament. Both direct and indirect inguinal hernias lie above the inguinal ligament.

44
Q

During development of the gut, the midgut loop is connected to the yolk sac via which structure?

A. Allantois
B. Umbilical vein
C. Vitelline duct

A

C. Vitelline duct

During early development of the embryo the midgut is connected to the yolk sac via the vitelline duct. This should obliterate but if it remains then a number of abnormalities are possible ranging from a vitelline fistula (faecal matter passing out of umbilicus) to a Meckel’s diverticulum.
The allantois is a structure that becomes the urachus (connecting the developing bladder to the yolk sac).
The umbilical vein delivers oxygenated blood to the developing fetus.

45
Q

What is the longest section of the GI tract?

A. Oesophagus
B. Duodenum
C. Jejenum
D. Ileum
E. Ascending colon
A

D. Ileum

The ileum is roughly 3.5 m long which makes this the longest section of the gut (closely followed by the jejunum). The point here is that the small intestine is much longer (and narrower) than the large intestine.