GI: Virulence Factors

Question 1

the etiological agents of dental caries have what key virulence factors?

Answer 1

s. mutans, s. sobrinus m/c (& lactobacillus, actinomyces, bidifobacterium)

1. adhesins
2. acidogeneticity
3. aciduricity
4. synthesis of EPS (extracellular polymers)
5. production of intracellular polysaccharides

Question 2

how do adhesins contribute to he virulence of dental caries agent?

Answer 2

they allow initial binding to the surface of the tooth

Question 3

how does acidogenicity contribute to the virulence of dental caries agents?

Answer 3

enables the agents to convert the surrouding sucrose / other carbohydrates (from the food we eat) into lactic acid via fermentation

Question 4

how does aciduriticy contribute to the virulence of dental caries agents?

Answer 4

enables the agents to survive & grow in the acidic environment they are generate when they ferment sucrose

Question 5

how does synthesis of EPS contribute to the virulence of dental caries agents?

Answer 5

EPS (extracellular polymers) allow the agents to consolidate attachment of plaque to the tooth

Question 6

how does production of intracellular polysaccharides contribute to the virulence of dental caries agents?

Answer 6

enables the agents to convert any excess sucrose / other carbohydrates into a storage form that can be utilized for fuel during a time when carbohydrates are not available