GI Tract Regulation And Structure

Question 1

Gastrin
Site of release
Cause of release
Actions

Answer 1

Site: G cell sin the atrium of the stomach
Cause: small peptides, AA’s, gastric distention, vagal stimulation
Actions: stimulates acid secretion

Question 2

CCK
Site
Releaser
Action

Answer 2

Site: I cells of duodenum/jejunum
Releaser: small peptides, AA's, FA's
Actions: 
Stimulates=galbladder contraction, pancreatic enzyme secretion/bicarbonate secretion, satiety
Inhibits: gastric emptying

Question 3

Secretin
Site
Releaser
Action

Answer 3

Site: S cells duodenum
Releaser: acid
Action: 
Stimulate=pancreatic bicarbonate secretion/biliary bicarbonate production
Inhibit: gastric acid secretion

Question 4

GIP
Site
Releaser
Actions

Answer 4

Site: K cells in the duodenum and jejunum
Releaser: FA's, AA's, oral glucose
Actions
Stimulates=insulin release
Inhibits=gastric acid secretion

Question 5

Motillin
Site
Releaser
Action

Answer 5

Site: duodenum and jejunum
Releaser: nerves
Actions:
Stimulates=gastric and intestinal motility

Question 6

Somatostatin
Site
Releaser
Action

Answer 6

Site: D cells in GI mucosa
Releaser: acid
Action:
inhibits: GI hormone release and gastric acid secretion

Question 7

Histamine
Site
Releaser
Action

Answer 7

Site: ECL cells
Releaser: gastrin
Action:
Stimulates=gastric acid secretion

Question 8

VIP
Site
Releaser
Action

Answer 8

Site: GI mucosa and SM
Releaser: released from nerves in the mucosa and SM of the GI tract
Actions: relaxes GI SM
Stimulates: intestinal secretion and pancreatic secretion

Question 9

GRP
Site
Releaser
Action

Answer 9

Site: gastric mucosa
Releaser: vagal stimulaton
Action: stimulate gastrin release

Question 10

Enkephalins
Site
Releaser
Action

Answer 10

Site: GI SM and mucosa
Releaser: secreted from nerves in the nerves and SM
Action:
Stimulate contraction of SM
Inhibit intestinal secretion

This is why opioids cause constapation