GI Procedures Flashcards
In what area of the GI does digestion begin?
Oropharynx
What are three examples of pathological processes that can affect swallowing?
- Pharyngeal tumor.
- CVA.
- Metabolic toxin.
Where is the esophagus located?
Begins at C6 and ends at the level of the stomach.
What are the three functional zones of the esophagus?
- Upper esophageal sphincter (UES)
- Esophageal body.
- Lower esophageal sphincter (LES).
Where does the esophagus pass through to the abdominal cavity?
A space created by the right crus of the diaphragm.
What are the three layers of the esophagus?
- Outer longitudinal layer.
- Inner circular muscular layer.
- Mucosal lining.
T/F: The esophagus is more vascular than the trachea and therefore more prone to bleeding?
False; trachea is more vascular
What artery is the main blood supply to the cervical esophagus?
Inferior thyroid arteries.
What artery is the main blood supply to the thoracic esophagus?
Aorta esophageal branches of bronchial arteries.
The extrinsic innervation of the esophagus is largely controlled parasympathetically by what nerves?
Cranial nerves IX, X, XI.
Are the UES and LES open or closed at rest?
Closed
Excitatory stimulation of UES occurs during what 5 normal body functions?
- Inspiration
- Esophageal distention.
- Gagging.
- Valsalva maneuver.
- Acidity of gastric contents.
UES tone is reduced by what 3 body functions?
- Distention
- Belching
- Vomiting.
What is the average velocity if esophageal peristalsis?
3-4cm/sec
Does esophageal peristalsis cause high or low pressure?
High pressure up to 150mmHg and can cause tears and ruptures
What affect does swallowing have on LES tone?
Decreases LES within 1.5-2.5 seconds and last 6-8 seconds
What affect does ingestion of a meal have on LES tone?
Increases LES tone via vagal afferent pathways.
What is normal LES tone in mmHg?
20mmHg
What 4 things can chronic alcoholism have on esophageal health?
- impaired esophageal peristalsis.
- LES hypotonia.
- Degeneration of the Auerbach Plexus (more likely to have tears)
- Mallory Weis Tear.
What is achalasia?
Failure of the lower esophageal sphincter tone to relax during swallowing accompanied with a lack of peristalsis.
What are 4 chronic disease states that can cause achalasia?
- Diabetes.
- Stroke.
- Amyotrophic lateral sclerosis.
- Connective tissue diseases
What is Barrett esophagus?
Normal squamous epithelium changes to metaplastic columnar epithelium
What is the typical focus of treatment for Barrett esophagus?
Acid reduction
What three things are likely the cause of Barrett esophagus?
- Chronic exposure to acid (GERD).
- Chronic alcohol abuse.
- Smoking
What other pathology is Barrett Esophagus closely associated with?
Esophageal carcinoma (Cancers)
What is the cause of GERD?
Failure of the LES to function properly (permits reflux of stomach contents into esophagus).
What is the current medical management therapy for GERD?
PPI and H2 blockers.
In GERD, what is more important- decreasing amount of acid or decreasing the level of acidity (increasing pH).
Decreasing amount of acid.
Which type of hiatal hernia is characterized by the stomach folding over on itself and passing through the opening?
Type 2/ Paraesophageal
Describe a type 1 Hiatal hernia:
Esophagus and stomach slide upward through the opening.
What are the primary symptoms of hiatal hernia?
Retrosternal pain or burning that commonly occurs after meals.
What is a Nissen fundoplication?
Treatment for hiatal hernia by folding stomach over on itself to prevent stomach from being able to move upwards.
What are the 3 classes of esophageal diverticula?
- Epiphrenic
- Traction
- Zenker
What are Zenker esophageal diverticula located? Traction?
Epiphrenic?
Zenker=upper esophagus
Traction=mid esophagus
Epiphrenic=Near the LES
Which type of esophageal diverticula is associated with highest likelihood of aspiration?
Zenker because it is closer to the airway.
What else causes increased risk of aspiration/airway complications with esophageal diverticular?
Not being able to swallow saliva
Why are patients with esophageal carcinoma prone to malnourishment?
pain/difficulty with swallowing
What major complications can arise from daunorubicin/doxoribicin ?
Chemotherapy induced cardiomyopathy
What major complication can arise form belomycin administration?
Pulmonary fibrosis
What four anesthesia considerations are required with esophageal disease?
- Plan for aspiration prophylaxis with induction/emergence.
- Mandates use of ETT.
- RSI
- Patient must be fully awake and demonstrate control of airway prior to extubation
For what disease/pathophysiology is an Ivor-Lewis repair done?
Esophageal cancer
What is the best way to optimize the patient’s health status prior to repairs of obstructive esophageal disease?
Admit 1 day early to optimize fluid therapy and electrolytes
For esophageal cancer cases, what four things are important for the SRNA to know?
- It is a large procedure
- What positioning entails/is needed
- Where the incisions will be
- These patient are high risk of hemorrhaging
What 5 intraoperative complications for esophagea; resection are important to remember?
- Arrhythmias
- Hypotension
- Injury to RLN
- Injury to tracheobronchial tree.
- Hemorrhage
What are the 4 most common post op complications of esophageal resection?
- anastomotic leak
- Mediastinitis.
- Sepsis
- Resp failure
What is the mortality rate for esophageal resection?
3%
What are the two anatomic sections of the stomach?
Fundus and Distal stomach
Which anatomic section of the stomach is characterized by thin-walled and distensible?
The fundus
What is the primary function of the fundus?
Storage for about 4 hours
What is the primary function of the distal stomach?
Slow release of chyme and mixing of food
What three things activate acid release via the parietal cells?
- Vagal stimulation
- Gastrin release
- Histamine
What affect do anticholinesterase drugs have on the stomach?
Muscarinic effects increase ACh which increases secretions.
What does a vagotomy do for gastric acid secretion?
Lysing some of the cells diminishes parietal cell response to gastrin and histamine.
What 3 classes of drugs are primarily used to control gastric acid secretion?
- H2 antagonist
- H+/K+ ATP inhibitors
- Anticholinergics
What supplies blood to the stomach?
4 arteries
R and L Gastric arteries, R and L gastroepiploic
What are the 7 main causes of Peptic ulcer disease?
- Chronic over supply of gastric acid and pepsin
- H. Pylori
- Overuse of ASA or NSAIDs or corticosteroids
- Excessive alcohol consumption
5.tobacco use, - stress, or
- receiving
radiation therapy
Which treatment for peptic ulcer disease is associated with acute hypophosphotemia?
Aluminum containing antacids
Which peptic ulcer pharmacologic therapy binds to ulcer and coats the stomach lining?
Sucralfate
What are signs and symptoms of Milk-alkali syndrome?
Hypercalcemia
Alkalosis
Elevated BUN
Which peptic ulcer pharmacologic treatment is associated with prolonged effects of anesthetic drugs?
H2 antagonists because of CYP inhibition
What is the most effective antisecretory agent for peptic ulcer disease?
PPI
T/F: Surgical treatment for peptic ulcer disease is considered the first line treatment for patients?
False: only once medical therapy is exhausted
T/F: Only a very small percentage of gastric neoplasms are malignant?
False: Nearly all gastric neoplasms are malignant
What is primary exocrine function of pancreas?
Adjust duodenal pH
What is primary endocrine function of pancreas?
Insulin and glucagon production to meet physiologic needs
What are S/S of acute pancreatitis?
Extremely ill with severe abd pain, fever, nausea, vomiting, jaundice, hypotension, ileus, and external distortion of stomach on radiographs
What is management of acute pancreatitis?
NG suction, maintain intravascular volume, anticipate resp insufficiency, analgesia,
T/F: Pancreatic cancer is highly curable at nearly 95%?
False; cure rate is 5% or less
Why do patients with biliary blockage/disease become jaundice?
Biliary tract is excretory conduit for the liver and it gets backed up and dumps intravascularly.
What is the primary control of gallbladder contraction/secretion?
Hormonal through the action of cholecystokinin.
What are the three main functions of bile?
- Emulsify and enhance absorption of fats
- Provide excretory pathway for bilirubin, drugs, toxins, and IgA
- Maintain duodenal alkalization
What is Murphy’s sign?
Inspiratory effort accentuates pain (cholecystitis)
What should be the differential diagnosis with suspected cholecystitis?
Cardiac event.
R/O with serial enzymes and EKG
What diagnosis is used when removing gall bladder for stones? For ERCPs?
Cholelithiasis: Choledocholithiasis
What is Charcot triad?
Fever, chills, upper quadrant pain. (cholelithiasis)
What type of pain medications should be given for Kuhr’s sign (CO2)
Not opioids. Torodol is better
What is the length of the small intestine sections?
Duodenum 20cm.
Jejunum 100cm.
Ileum 150cm.
What is the main role of plicae circulares?
Increase surface area of small intestine.
Anesthetic considerations for small bowel obstruction?
- RSI
2. OG/NG prior to induction
Which three arteries supply blood to the large intestine?
- superior mesenteric artery.
- Inferior mesenteric artery
- Internal iliac artery.
T/F: Diverticulitis is the simply the presence of diverticulum?
False: diverticulosis is simply the presence of diverticulum; whereas, diverticulitis is an inflamed/causing issue
In which disease state is the wall thickened and can “cobble stoning” (UC or CD)?
Crohn’s disease
UC/CD: Which one can present at certain areas in the large intestine and not others (sort of jumps around)?
Crohns disease
T/F: For intestinal surgery, N2O should be the primary inhaled anesthetic used?
False