GI Pharmacology Flashcards

1
Q

What are the neuronal, paracrine, and endocrine regulators of gastric secretions?

A

Mucus: Ach, Prostaglandins
Acid: Histamine, Acetylcholine, Gastrin, Prostaglandin inhibits H

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2
Q

Aluminum Hydroxide
MOA:
AE:
Interactions:

A

MOA: Antacid, slow effect, short duration of action, Constipation
AE: red drug bioavailability, Infection
Interactions: common combo with magnesium hydroxide to offset constip

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3
Q

Bismuth Subsalicylate
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions:

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4
Q

Calcium Carbonate
MOA:
AE:
Interactions:

A

MOA: Antacid, acid rebound, gas/bloat,
AE: Reduced drug bioavailability, infection
Interactions:

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5
Q

Cimetidine
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions:

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6
Q

Esomeprazole
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions:

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7
Q

Famotidine
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions:

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8
Q

Lansoprazole
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions:

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9
Q

Magnesium hydroxide
MOA:
AE:
Interactions:

A

MOA: Antacid. Slow effect. osmotic diarrhea
AE: Reduced drug bioavailability, infection
Interactions: Commoon combo with aluminum hydroxide to offset diarrhea

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10
Q

Misoprostol
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions:

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11
Q

Nizatidine
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions:

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12
Q

Omeprazole
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions:

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13
Q

Pantoprazole
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions:

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14
Q

Rabeprazole
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions:

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15
Q

Ranitidine
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions:

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16
Q

Sodium bicarbonate
MOA:
AE:
Interactions:

A

MOA: Antacid, cause met alkalosis, fast effect, short term, gas/bloat, salt absorption
AE: Reduced drug bioavailability, infection
Interactions:

17
Q

Sucralfate
MOA:
AE:
Interactions:

A

MOA:
AE:
Interactions: