GI/Nutrition 2 Flashcards
complication of gallstones 2/2 to infected obstruction of the cbd
cholangitis
mcc of cholangitis
e. coli
charcot’s triad
ruq pain
jaundice
fever
reynold’s pentad
charcot’s triad
PLUS
hypotn
AMS
besides reynold’s pentad, 2 additional sx of cholangitis
light colored stool
tea colored urine
pruritis + jaundice =
primary sclerosing cholangitis
chronic liver dz involving inflammation/fibrosis of the intrahepatic and extrahepatic ducts
primary sclerosing cholangitis
what pt pop makes you think of primary sclerosing cholangitis
ulcerative colitis
cholangiography finding of PSC
fibrosis of bile ducts
imaging for cholangitis: initial vs gs
initial: US
gs: ERCP
indication to skip US and proceed directly to ERCP w. suspected cholangitis
charcot’s triad + abnl LFTs
management of cholangitis
empiric abx
ercp w. stent
post acute cholecystectomy
all causes of cholangitis (6)
cholelithiasis
post op choledocholithiasis stricture
neoplasm (ampullary carcinoma)
pancreatic pseudocyst/pancreatitis
ERCP/PTC
biliary stent
lab elevations associated w. cholangitis
elevated: WBC, bilirubin, ALP
positive blood cultures
what is supporative cholangitis
severe infxn w. sepsis
“pus under pressure”
tx for supporative cholangitis
IVF
abx
decompression: ERCP w. papillotomy vs PTC w. catheter drainage vs laparotomy w. T-tube
cystic collection of tissue, fluid, and necrotic debris surrounding the pancreas
pancreatic pseudocyst
2 conditions associated w. pancreatic pseudocyst
pancreatic (chronic > acute)
trauma to chest (ex steering wheel)
pancreatic pseudocysts generally occur how long after acute pancreatitis
2-3 weeks
characteristic appearance of pancreatic pseudocyst
fibrous capsuel w. no epithelial lining
PE finding of pancreatic pseudocyst
abdominal mass
indication for surgical intervention w. pseudocyst
if persists past 4-6 weeks:
percutaneous drainage vs pancreaticogastrostomy
complications of pancreatic pseudocyst (7)
infxn -> pertonitis
bleeding
fistula
pancreatic ascites
gastric outlet obstruction
SBO
biliary obstruction
mcc of pancreatic pseudocyst
chronic alcoholic pancreatitis
tumor marker associated w. liver ca
AFP
3 rf for hepatic carcinoma
hepatitis B and C
hemochromatosis
cirrhosis
benign liver lesions
cavernous hemagioma
hepatocellular adenoma
infantile hemangioendothelioma
imaging guidelines for liver lesions
< 1 cm: contrast MRI w. f/u US q 3 mo
guidelines for HCC screening
+/- pt’s w. cirrhosis and chronic hep B
screen w. periodic AFP and US
tx for HCC
-transplant: single tumors < 5 cm OR </= 3 cm limited to the liver
-resection - high rate of recurrence
epigastric pain that radiates to the back + wt loss, jaundice, pruritis
pancreatic ca
most clearly established rf for pancreatic ca
smoking
mc location for pancreatic ca
head of the pancreas
tx for pancreatic ca
pancreaticoduodenectomy (whipple)
tumor marker for pancreatic ca
CA-19-9
what is courvoisier’s sign
nontender, palpable gallbladder
mc type of pancreatic ca
ductal adenocarcinoma at the head of the pancreas
5 rf for pancreatic ca
cigs
etoh
pancreatitis
dm
obesity
what is virchow’s node
signal node in the left supraclavicular fossa
the pain of pancreatitis/pancreatic ca is relieved by
sitting and leaning forward
labs of pancreatic ca
-elevated: amylase, direct bilirubin, CEA, CA19-9
-glucose intolerance
what happens in a whipple procedure
removal of: antrum, part of duodenum, head of pancreas, gallbladder
results in:
-choledochojejunostomy: bile flow
-gastrojejunostomy: passage of food
-pancreaticojejunostomy: pancreatic juice flow
2 types of hiatal hernia
type 1: sliding -> mc
type 2: paraesophageal
describe hiatal hernia
both gastroesophageal junction AND portion of the stomach herniate into the thorax -> gastroesophageal junction is above the diaphragm
describe paraesophageal hiatal hernia
gastroesophageal junction remains below the diaphragm
which type of hiatal hernia is high risk for strangulation
paraesophageal
hiatal hernias are mc asymptomatic, but what are 3 possible sx
heartburn
chest pain
dysphagia
complications of sliding hiatal hernia
reflux esophagitis
barrett’s/esophageal ca
aspiration
3 complications of paraesophageal hiatal hernia
obstruction
hemorrhage
incarceration/strangulation
dx for hiatal hernia
barium upper GI studies
upper endo
tx for hiatal hernia - type 1 vs type 2
type 1: antacids, lifestyle, +/- nissen fundoplication
type 2: nissen fundoplication
what part of the GIT is usually spared w. crohn’s
rectum
if rectum is involved, think UC
pattern of involvement w. crohn’s vs UC
crohn’s: skip lesions
UC: continuous
which type of IBD involves bloody diarrhea
UC
which type of IBD involves severe abd pain
crohn’s
what type of IBD is associated w. perianal dz
crohn’s
which type of IBD involves fistulas
crohn’s
ulcers associated w. crohn’s vs UC
crohn’s: aphtoid/deep ulcers, cobblestoning
UC: erythematous/friable/superficial ulcers
what is this showing
deep ulcers -> crohn’s
what is this showing
cobblestoning -> crohn’s
4 radiographic findings of crohn’s
string sign
RLQ mass
fistula
abscesses
radiographic finding of UC
tubular lead pipe appearance
what is this showing
string sign of terminal ileum -> crohn’s
what is this showing
lead pipe apperance -> UC
histologic features of crohn’s vs UC
crohn’s: transmural, non caseating granulomas
UC: mucosa-only crypt abscesses
association of smoking: crohn’s vs UC
crohn’s: worsens
UC: protective
serology associated w. crohn’s vs UC
crohn’s: ASCA
UC: p-ANCA
common presentation of UC (4)
bloody pussy diarrhea
rectal/lower quadrant pain
fever
urgency
mc site for UC
rectum
lab findings of UC
elevated: WBC, ESR
anemia
2 complications of UC
toxic megacolon
colorectal ca
4 systemic sx of crohn’s
oral/aphtous ulcers
severe anemia
polyarthralgia
fatigue
mc site for crohn’s
terminal ileum
4 complication of crohn’s
strictures
obstruction
abscess
fistula
work up for IBD (3)
upper GI series
colonoscopy w. bx
serology
most valuable dx test for IBD
colonoscopy
consider _ over colonoscopy in UC to reduce risk of bowel perf
flex sigmoidoscopy
complication of UC
toxic megacolon
mainstay of pharm for IBD
5-aminosalicylic acid drugs (ex sulfasalazine)
t/f: UC is more common in smokers and ex smokers
t!
GIB, fulminant colitis, toxic megacolon
UC
fistulas and renal stones
crohn’s