GI/Nutrition Flashcards
epigastric pain that radiates to right subscapula
cholecystitis
7 causes of epigastric pain
PUD
gastritis
MI
pancreatitis
biliary colic
gastric volvulus
mallory-weiss tear
mcc of llq pain
diverticulitis
mcc of rlq pain
appendicitis
RUQ pain + fever + leukocytosis
cholecystitis
5 f’s of cholecystitis
female
fat
forty
fertile
fair
preferred imaging vs gs imaging for cholecystitis
preferred: US
gold standard: HIDA
3 US findings of cholecystitis
gallbladder wall > 3 mm
pericholecystic fluid
gallstones (duh)
complication of chronic cholecystitis
porecelain gallbladder
epigastric pain that radiates to the back + n/v
pancreatitis
2 etiologies of pancreatitis that Smarty PANCE wants us to know
cholelithiasis
etoh
gs imaging for pancreatitis
CT
what is this sign
grey turner’s -> pancreatitis
what is this sign
cullen’s -> pancreatitis
ranson’s criteria for poor prognosis w. pancreatitis
at admit:
age > 55
leukocytosis > 16,000
glucose > 200
LDH > 350
AST > 250
at 48 hr:
arterial PO2 < 60
HCO3 < 20
Ca < 8.0
BUN increase by 1.8
Hct decrease by > 10%
fluid sequestration > 6 L
what is this showing
pancreatic pseudocyst: circumscribed collection of fluid rich in pancreatic enzymes, blood, necrotic tissue
complication of pancreatitis
chronic pancreatitis triad
pancreatic calcification
steatorrhea
DM
3 anal topics to know
fissure
abscess
fistula
hallmark sx of anal fissure
blood on outside of stool or in toilet following BM
anal fissures are extremely common in what pt pop
infants
mc type of anal fissure
vertical
horizontal anal fissures make you think of (2)
crohn’s
HIV
tx for anal fissures (3)
most self resolve
stool softeners
pteroleum jelly
complication of anal fissure
anal abscess
2 mcc of anorectal abscess
STDs
blocked anal glands
2 mcc of deep rectal abscesses
crohn’s
diverticulitis
tx for anorectal abscess (4)
I&D
sitz bath
pain control
abx
complication of deep anorectal abscess
anorectal fistula
Smarty PANCE wants you to think about _ w. anorexia
appendicitis
classic progression of appendicitis
periumbilical -> n/v -> anorexia -> RLQ pain
over 24 hr
besides appendicitis, what other conditions does anorexia make you think of (5)
ulcers
lower GI bleed
GI cancers
thyroid dz
meds
mnemonic for sx of gastric ca
weapon:
weight loss
emesis
anorexia
pain
obstruction
nausea
6 sx of lower GI bleed
brbpr
anorexia
fatigue
syncope
SOB
shock
sx of pancreatic carcinoma
painless jaundice
wt loss
abd pain
back pain weak
pruritis
acholic stool
dark urine
DM
6 meds associated w. anorexia
sedatives
digoxin
laxatives
thiazides
narcotics
abx
4 PE signs associated w. appenditicis
mcburney’s point: rebound tenderness
rovsing: RLQ pain w. palpation of LLQ
obturator: RLQ pain w. internal hip rotation
psoas: RLQ pain w. hip extension
CBC finding of appendicitis
neutrophilia
mcc of pancreatitis: acute vs chronic
acute: gallstones
chronic: etoh
1/3 of pancreatic ca can be attributed to (2)
smoking
etoh
tumor marker present in 80% of pancreatic ca
CA 19-9
what is PONV
post op nausea/vomiting
3 emotogenic drugs commonly used in anesthesia
nitrous oxide (N2O)
opioids
phyostigmine
3 surgeries mc associated w. PONV
cholecystectomy
gynecologic
laparoscopic
least emetogenic general anesthetic
propofol
dx for PONV
PONV scale:
female
nonsmoker
hx of motion sickness/prev PONV
expected use of postop opioids
score of 0,1, 2 ,3 ,4 = 10-80% risk respectively
tx for PONV (2)
preoperative fasting x 2-6 hr
antiemetics
name 5 antiemetics
scopolamine patch
dexamethasone
ondansetron
prochlorperazine
droperidol
name 2 rescue antiemetics administered in PACU
prochlorperazine
droperidol
sx of upper GI bleed
coffee ground hematemesis
+/- melena
first consideration in eval of upper GI bleed
evaluate hemodynamic stability
5 symptoms that suggest severe upper GIB
orthostatic hypotn
confusion
angina
palpitations
cold/clammy extremities
5 causes of upper GIB
peptic ulcer
esophageal ulcer
mallory-weiss tear
variceal hemorrhage
malignancy
sx of blood loss based on severity: 15% loss - 40% loss
15%: resting tachy
15-39%: orthostatic hypotn
>/= 40%: supine hypotn
define orthostatic hypotn
decrease in systolic bp > 20 mmHg and/or increase in HR of 20 bpm moving from sitting to standing
management of upper GIB (2)
IVF asap
transfusion
indications for transfusion (5)
hemodynamically unstable despite IVF
Hgb < 9 in high risk pt
Hgb < 7 in low risk pt (most pt’s)
active bleeding + PLT < 50,000
INR > 2.0 not due to cirrhosis
appendicitis is unlikely if the patient is _
hungry
what is obstipation
severe or complete constipation
2 XR findings of bowel obstruction
air fluid levels
dilated loops of bowel
2 types of bowel obstruction
small
large
5 sx of SBO
colicky abd pain
nausea w. bilious vomiting
obstipation
abd distension
high pitched BS -> hypoactive BS
5 sx of LBO
gradually increasing abd pain
longer intervals btw pain
abd distension
obstipation
less vomiting than SBO
3 hallmark sx of bowel obstruction
vomiting partially digested food
svere abd distension
hyperactive BS -> hypoactive BS
what is this showing
dilated loops of bowel
air fluid levels
little/no gas in colon
bowel obstruction
management of bowel obstruction (3)
NGT
hemodynamic monitoring
laparotomy
indication for surgery w. bowel obstruction
no resolution w. 24-48 hr of conservative managment
sudden onset of significant, colicky abd pain that recurs q 15-20 min w. vomiting
small bowel intussusception
3 pt pops that make you consider intussusception
post GI op
kiddos after viral infxn
adults w. cancer
90% of intussusception involves what part of the bowel
ileocecal junction
2 hallmark sx of intussusception
currant jelly stool
sausage like mass in abd
3 imaging findings of intussusception
crescent sign
bull’s eye/target sign
coiled spring lesion
what is this showing
target sign -> intussusception
what is this showing
meniscus/crescent sign -> intussusception
dx AND tx for intussusception in kiddos
barium enema
general management of intussusception (5)
-NPO
-NGT
-IVF
-barium enema
-manual reduction/resection w. anastomosis
clinical definition of post op adynamic ileus/paralytic ileus
ileus that persists > 3 days post op
what is an ileus
hypomotility of GIT in absence of mechanical bowel obstruction
hallmark sx of ileus
absent bowel sounds
gs imaging for ileus
CT w. gastrografin
management of ileus
mc self resolves x 2-3 days
condition that affects stomach muscles and prevents proper stomach emptying
gastroparesis
mcc of gastroparesis
DM
all causes of gastroparesis (6)
dm
anorexia
bulimia
scleroderma
ehlers-danlos
abd surgery
2 hallmark sx of gastroparesis
nausea
early satiety
dx for gastroparesis (3)
gs: gastric emptying scan
KUB
manometry
management of gastroparesis (3)
low fiber/low residue diet/low fat diet
small, frequent meals
metoclopramide (reglan)
moa for reglan
d2 receptor antagonist -> increases contractility/resting tone in GIT
inflammation of the colon caused by cdiff
pseudomembranous colitis
3 abx mc associated w. pseudomembranous colitis
pcn
cephalosporins
broad spectrum abx
what pt pop should you think about w. pseudomembranous colitis
elderly hospitalized
pseudomembranous colitis relies on the secretion of what 2 toxins, which dusrupt normal colinic flora
A - enterotoxin
B- cytotoxin
hallmark sx of pseudomembranous colitis
mild foul-smelling watery diarrhea
>3 but < 20/day
t/f: pseudomembranous colitis is commonly associated w. fever
t!
dx for pseudomembranous colitis
PCR
which cdiff toxin is clinically important
toxin b
tx for pseudomembranous colitis
IV metro
vs
PO vanco
2 complications of pseudomembranous colitis
bowel perf
toxic megacolon
only proven method to reduce and maintain wt loss and reduce obesity related morbidities/mortalities
bariatric surgery
NIH guidelines for indications for bariatric surgery (5)
BMI > 40
BMI > 35 + obesity related problem
failed non surgical wt. loss programs
psychologically stable to follow post op care
obesity NOT due to medical dz (ex endocrine)
3 mechanisms that bariatric surgery uses to reduce energy intake in obese pt’s
restrictive
malabsorptive
combo: restrictive + malabsorptive
3 types of restrictive bariatric surgery procedures
adjustable gastric banding (AGB)
vertical banded gastroplasty (VBG)
sleeve gastrectomy (SG)
2 types of bariatric malabsorptive procedures
-biliopancreatic diversion (BPD)
-biliopancreatic diversion w/w.o duodenoal switch (BPD/DS)
combo malabsorptive/restrictive bariatric surgery procedure
roux-en-y gastric bypass (RNYGB)
4 mc bariatric procedures used in the US
RNYGB
AGB
VSG
BPD/DS
describe roux-en-y
-bypass: stomach, duodenum, 100-150 cm of SI
-creates a restrictive pouch
-roux limb (gastrojejunostomy): limits absorption
2 complications of RYGB that Smarty PANCE stresses
dumping syndrome
mortality 1/500
what gastric bypass procedures is restrictive and hormonal
VSG
describe VSG
-resection stomach along greater curvature, including fundus ->
-reduces stomach to < 25% volume
-decreased ghrelin due to removal of fundus
what type of bariatric surgery is restrictive only
ABG
ideal candidate for ABG
volume eater
trains pt to eat and chew slower
downsides of ABG (4)
regurgitation
annual barium swallow study
less wt loss
hiatal hernias must be repaired first
3 complications of ABG
band slippage
prolapse
dilation
mc bariatric surgery for tx of severe obesity in US
RNYGB
what type of bariatric surgery leaves the pylorus and stomach innervation intact
SG
what types of bariatric surgeries are not commonly used due to complications and malnutrition
BPD
DS
5 early complications of bariatric surgery
anastomitic leak
DVT/PE
bleeding
infxn
splenic injury
8 late complications of bariatric surgery
malnutrition
ulcer
anastomotic strictures
internal hernia
cholelithiasis
band slippage
band erosion
esophageal dilatation
mcc of esophageal stricture
GERD
2 PMH clues for esophageal stricture
solid food dysphagia
GERD
infectious esophagitis causes what type of esophageal stricture (2)
proximal
mid
NOT distal
schatzki ring is mc associated w. what condition
hiatal hernia
triad of plummer-vinson syndrome
dysphagia
esophageal webs
IDA
thin membrane in mid-upper esophagus that is congenital vs acquired
esophageal web
esophageal strictures are often due to
healing process of ulcerative esophagitis
diaphragm like mucosal ring that forms at the esophagogastric junction (B ring)
schatzki ring
when do sx usually occur w. schatzki ring based on size
> 20 mm: few sx
< 13 mm: severe/chronic sx
schatzki rings are found in 6-15% of pt’s who have undergone
barium swallow study
typical presentation of schatzki ring
intermittent/nonprogressive dysphagia for solids after consuming heavy meal w. meat that was wolfed down
steakhouse syndrome
dx and tx for schatzki ring
dx: barium swallow/endoscopy
tx: dilation via rupture
what is this showing
esophageal web
first line diagnostic study in elderly man presenting w. dysphagia
esophagoscopy
major risk factor for adenocarcinoma of the esophagus leading to barrett esophagus
GERD
adenocarcinoma of the esophagus mc occurs at what part of the esophagus
lower third
2 main types of esphageal ca
squamous cell carcinoma
adenocarcinoma
mcc of both types of esophageal ca
adenocarcinoma: GERD/barrett’s
squamous cell: smoking vs etoh
7 sx of esophageal ca
dysphagia of solids -> liquids
regurgitation
heartburn
LAD
wt loss
hematemesis
chest pain unrelated to eating
dx for esophageal ca (3)
barium swallow
endoscopy/bx
MRI vs thoracic CT
tx of choice for esophageal ca that has NOT metastasized
surgery
mc type of esophageal ca worldwide vs US
worldwide: squamous
US: adeno
gs dx for esophageal ca
upper endoscopy w. bx
indication for endoscopic screening for esophageal ca
pt’s w. barrett’s q 3-5 years
90% of gallstones are:
10% are:
90%: cholesterol
10%: pigmented
10 rf for cholelithiasis
5 f’s
ocp’s
chronic hemolysis
cirrhosis
infxn
rapid wt loss
ibd
tpn
fibrates
elevated TG
3 complications of cholelithiasis
cholecystitis
choledocholithiasis
cholangitis
when should US for cholelithiasis be performed
after 8 hr of fasting
distended/bile filled gallbladder is best to visualize stones
2 types of pigmented gallstones
black: calcium bilirubinate
brown: biliary tract infxn
2 causes of black gallstones
cirrhosis
hemolysis
t/f: hypercholesterolemia is a rf for gallstones
f!
hyperlipidemia is tho
referred right subscapular pain of biliary colic
boas sign -> cholelithiasis
4 complications of lap chole
cbd injury
right hepatic duct/artery injury
cystic duct leak
biloma
3 indications for cholecystectomy in asymptomatic pt
ssa
porecelain gallbladder
kiddo
gs dx/tx for choledocholithiasis
ercp
what med may dissolve cholesterol gallstone
chenodeoxycholic acid (actigall)
screening recs for colorectal carcinoma
all adults 45-75 yo
+/- 76-85 yo
screening options for pt’s with no rf for colorectal ca (4)
colonoscopy q 10 years
flexible sigmoidoscopy q 5 years
double contrast barium enema q 5 years
circulating tumor cells q 5 years
screening for colorecta cal for pt w. adenomatous polyps OR colon ca in first degree relative
colonoscopy at 40 or 10 years younger than first relative was dx
3 highest risk factors for colorectal ca that indicate colonoscopy at any age
IDB
hereditary non polyposis colorectal ca
familial adenomatous polyps
progression of adenomatous polyp into malignancy (adenocarcinoma) usually occurs w.in _ years
10-20 years
7 known rf for colorectal ca
age > 45
IBD
polyps
low fiber diet
high animal fat diet
smoking
etoh
2 hallmark sx of colorectal ca
painless rectal bleeding
change in bowel habits
3 stool tests for colorectal ca
guaiac based fecal occult (FOBT) annually
fecal immunochemical test (FIT) annually
FIT-DNA q 1-3 years
what is this showing
apple core lesion on barium enema -> colorectal adenocarcinoma
2 lab findings of colorectal carcinoma
elevated CEA
anemia
tx for colorectal carcinoma (3)
surgical resection
5 FU chemo
monitor CEA
what is lynch syndrome
-hnpcc: hereditary non polyposis colon ca
-autosomal dominant
-high risk of colon ca
sx of colon ca: right vs left sided lesion
right: microcytic anemia, (+) FOBT, melena, postprandial discomfort, fatigue
left: change in bowel habits, colicky pain, obstruction, abd mass, BRBPR, hematemesis, constipation
melena is mc from what type of colorectal ca
right sided
hematochesia is mc w. what type of colon ca
left sisded
microcytic anemia is _ until proven otherwise in a man or postmenopausal woman
colorectal ca
3 mcc of colonic obstruction in adults
colon ca
diverticular dz
colonic valvulus
mc type of gastric carcinoma
adenocarcinoma
4 rf for gastric ca
fam hx
gastric ulcers
h pylori
prenicious anemia
5 sx of gastric ca
LOA
progressive dysphagia
vague feeling of abd fullness/early satiety
n/v
wt loss
dx for gastric carcinoma
egd w. bx
cbc
fobt
what type of anemia is associated w. gastric ca
microcytic hypochromic
only curative tx for gastric carcinoma
surgery
gastric carcinoma is extremely high in what 3 countries
japan
chile
iceland
sx that gastric ca has metastasized
virchow node
sister mary joseph nodule
what is this showing
sister mary joseph nodule
2-3 week old well fed infant who presents w. non bilious vomiting after most/every feeding
pyloric stenosis
common presentation of pyloric stenosis (3)
< 3 months old
projectile non bilious vomiting
olive shaped mass - pathognomonic
lab finding of pyloric stenosis
hypochloremic hypokalemic metabolic alkalosis
dx for pyloric stenosis
US vs UGI barium series
hallmark imaging sign of pyloric stenosis: US vs barium studies
US: double track
barium: string sign
what is this showing
string sign -> pyloric stenosis
tx for pyloric stenosis
pyloromyotomy - ramstedt procedure
hypertrophy of smooth muscle of pyloris -> obstruction of outflow
pyloric stenosis
rf pyloric stenosis
first born male
why is vomiting w. pyloric stenosis non bilious
obstruction is proximal to ampulla of vater
4 complications of pyloromyotomy
duodenal damage
bleeding
infxn
aspiration pna
post op feeding for pyloromyotomy
6-12 hr post op: pedialyte
24 hr: full strength formula
diverticulosis is mc found in the
sigmoid colon
s/sx of diverticulitis
f/c
n/v
left sided abd pain
2 hallmark imaging findings of diverticulitis
fat stranding
bowel wall thickening
mcc cause of lowr GIB
diverticulitis
abx used for diverticulitis
cipro vs augmentin
+/- flagyl
4 indications for colon resection w. diverticulitis
recurrent
perforation
fistula
abscess
lifestyle management of diverticulitis
high fiber diet
t/f: nuts and seeds are associated w. an increasein risk of diverticulosis, diverticulitis, or diverticular bleeding
f!!!!!!
thank you for acknowledging this Smarty PANCE!
the presence of what 3 factors acurately predicts acute diverticulitis
absence of vomiting
CRP > 5
tenderness limited to LLQ
gs dx for diverticulitis
CT w. contrast
what is absolutely contraindicated if you suspect diverticulitis in an acute setting
colonoscopy
risk of bowel perf
6 complications of diverticulitis
abscess
peritonitis
fistula
obstruction
perforation
stricture
mc fistula associated w. diverticulitis
colovesical (to bladder)
surgery mc performed for acute diverticulitis w. complications
hartmann’s: resection w. end colostomy
2 mc oragnisms associated w. development of diverticulitis
e. coli
b. fragilis