GI Neurohormones Flashcards

1
Q

ACH
Source??
Actions??

A
Cholinergic neurons
ACTIONS:
1. Contraction of smooth muscle in wall 
2. Relaxation of sphincters
3. Increase salivary secretion
4. Increase Gastric secretion
5. Increase Pancreatic secretion
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2
Q

Norepinephrine (NE)
Source??
Actions??

A
Adrenergic neurons
ACTIONS:
1. Relaxation of smooth muscle in wall
2. Contraction of sphincters
3. Increase salivary secretion
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3
Q

Vasoactive Intestinal Peptide (VIP)
Source??
Actions??

A
Neurons of mucosa and smooth muscle
ACTIONS:
1. Relaxation of smooth muscle
2. Increase intestinal secretion
3. Increase pancreatic secretion
4. Increase gastric secretion
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4
Q

Gastrin-Releasing Peptide (GRP), or Bombesin
Source??
Actions??

A

Neurons of gastric mucosa
ACTIONS:
1. Increase Gastrin secretion

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5
Q

Enkephalins (opiates)
Source??
Actions??

A

Neurons of mucosa and smooth muscle
ACTIONS:
1. Contraction of smooth muscle
2. Decrease Intestinal secretion

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6
Q

Neuropeptide Y
Source??
Actions??

A

Neurons of mucosa and smooth muscle
ACTIONS:
1. Relaxation of smooth muscle
2. Decrease intestinal secretion

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7
Q

Substance P
Source??
Actions??

A

CO-SECRETED WITH ACh
ACTIONS:
1. Contraction of smooth muscle
2. Increase salivary secretion

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