GI Motility 4 Flashcards

1
Q

What 4 physiological processes is the GI system involved in?

A
  • Motility
  • Secretion
  • Digestion
  • Absorption
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2
Q

Which nervous system controls the GI system?

A

Enteric nervous system

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3
Q

What are the 4 accessory glands to the GI system?

A
  • Salivary glands
  • Liver
  • Gallbladder
  • Pancreas
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4
Q

What type of muscle makes up sphincters?

A

Smooth muscle

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5
Q

What are the layers of the gut wall (lumen to abdominal cavity)?

A
  • Mucosa
  • Submucose
  • Muscular externa
  • Serosa
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6
Q

Which nerve plexus regulates gut motility?

A

Myenteric nerve plexus (Auerbach’s)

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7
Q

Which nerve plexus regulates blood flow and secretion?

A

Submucosal nerve plexus (Meissner’s)

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8
Q

What does the myenteric nerve plexus innervate?

A

The longitudinal and circular smooth muscle layers

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9
Q

What does the submucosal nerve plexus innervate?

A
  • Glandular epithelium
  • Intestinal endocrine cells
  • Submucosal blood vessels
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10
Q

Innervations of the Vagus nerve.

A
  • Oesophagus
  • Stomach
  • Small intestine
  • Liver
  • Pancreas
  • Caecum
  • Appendix
  • Ascending colon
  • Transverse colon
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11
Q

What is the caecum?

A

A pouch that lies in between the small intestine (ileum) and the large intestine (ascending colon).

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12
Q

What does sympathetic and parasympathetic activity do to gut motility and secretion?

A
  • Sympathetic activity inhibits gut motility and secretion.

- Parasympathetic activity stimulates gut motility and secretion.

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13
Q

Where is the myenteric nerve plexus located?

A

Between the longitudinal and circular muscle layers.

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14
Q

Where is the submucosal nerve plexus located?

A

Between the circular muscle and submucosal layer.

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15
Q

What is Hirschsprung’s disease?

A

Congenital absence of the myenteric plexus, leading to a lack of peristalsis, spasms and constipation.

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16
Q

What are the 3 types of GI movement?

A
  • Segmentation
  • Peristalsis
  • Tonic contraction
17
Q

What is the migrating motor complex?

A

Strong contractions that pass down down the distal stomach and small intestine every 90 minutes.

18
Q

What is paralytic ileus?

A

Cessation of gut motility that is mainly caused by abdominal surgery (can also be caused by infection, inflammation, electrolyte abnormalities and drug ingestion).

19
Q

What is deglutition?

A

Swallowing

20
Q

What is mastication?

21
Q

What part of swallowing is under voluntary control?

A
  • The formation of a blue through mastication

- The propelling of the bolus to the oropharynx when the tongues moves up against the hard palate

22
Q

How is involuntary deglutition initiated?

A

1) Bolus stimulates mechanoreceptors in the pharynx

2) Glossopharyngeal afferent impulses are sent to the swallowing centre

23
Q

How does the body ensure that the bolus only travels down the oesophagus?

A
  • Soft palate elevates and blocks off the nasopharynx
  • Respiration is inhibited
  • Larynx rises so that the epiglottis covers the trachea.
24
Q

Which efferent nerve co-ordinates deglutition?

A

Vagus nerve which stimulates peristalsis to commence (starting from the pharynx).

25
What is the first sphincter that a bolus passes through?
Upper oesophageal sphincter (between pharynx and oesophagus)
26
What muscle is the oesophagus composed of?
- Upper 1/3 is skeletal muscle | - Lower 2/3 is smooth
27
How does a bolus reach the LOS from the UOS?
Peristalsis in the oesophagus transports the bolus from the UOS to the LOS
28
Which sphincter allows the the bolus to enter the proximal stomach from the oesophagus?
Lower Oesophageal Sphincter
29
What is dysphagia?
Difficulty in swallowing
30
What is gastric oesophageal reflux disease (GORD) and how is it caused?
- When the LOS is unable to close properly, allowing the contents of the stomach to flow back into the oesophagus. - Because it is corrosive to the oesophageal mucosa, the distal oesophagus becomes inflamed and sometime ulcerated.
31
What is receptive relaxation?
Mediated by the Vagus nerve and is when the stomach relaxes when food enters - allowing the pressure to remain constant.
32
Why does stomach emptying need to be controlled?
Because the small intestine has a limited capacity.
33
What is bacterial blind loop syndrome?
Impaired peristalsis in the small intestine, leading to high levels of bacteria - which can then cause diarrhoea.
34
What are haustrations?
The pouches formed when segmentation occurs in the large intestine.
35
What are the two sphincters involved in defecation?
- Internal anal sphincter (involuntary) | - External anal sphincter (voluntary via skeletal muscle)