GI + Liver Flashcards
Which IBD is associated with increased goblet cells
Crohn’s
65y/o woman with jaundice, weight loss and pale stools. Colicky RUQ pain and palpable mass
Cholangiocarcinoma
Which hernias have a low risk of strangulation
Direct and indirect inguinal hernias
What can cause an indirect inguinal hernia
Failure of the processus vaginalis to close
Typical presentation of diverticulitis
Elderly patient, LIF pain, diarrhoea and fever
Barrett’s oesophagus, dysphagia and weight loss
Oesophageal cancer
Hx of heartburn with odynophagia. No weight loss, vomiting or anorexia
Oesophagitis
Treatment for C.difficile infection
- Oral Vancomycin
- Oral fidaxomicin
Presentation of C.difficile infection
- Watery Diarrhoea
- Elderly patient
- Abdo pain
- Raised WCC - neutrophilia
- Post Ab treatment, e.g. pneumoniae
MC organism implicated in cholangitis infections
E.coli
Common side effect of statin therapy
- Myalgia
- Liver impairment
- Rhabdomyolysis - breakdown of muscle
Contraindications of statins
- Macrolides
- Pregnancy
Causes of ascites with a SAAG >11 g/L
Indicated portal HTN
* Liver disorders: Cirrhosis, ALD, ALF
* Cardiac: RHF, constructive pericarditis
* Other: Budd-Chiari, Portal vein thrombosis
Causes of ascites with a SAAG <11 g/L
- Hypalbuminaemia: nephrotic syndrome, severe malnutrition
- Malignancy
- TB peritonitis
- Bowel obstruction
Which clotting factor is paradoxically normal in liver failure
Factor VIII (8)
Synthesised in endothelial cells throughout body
