GI Hormones Flashcards
Gastrin:
Site of secretion
Stimulus
Action
G cells of antrum, duodenum, jejunum
Protein, distention, nerve
Stimulates gastric acid secretion, mucosal growth
Cholecystokinen (CCK):
Site of secretion
Stimulus
Action
I cells of duodenum, jejunum, ileum
Protein, fat and acid
Stimulates pancreatic enzyme secretion, pancreatic bicarb secretion, gallbladder contraction, growth of exocrine pancreas
Inhibits gastric emptying
Secretin:
Site of secretion
Stimulus
Action
S cells of duodenum, jejunum, ileum
Acid, fat
Stimulates pepsin secretion, pancreatic bicarb secretion, biliary bicarb secretion, growth of exocrine pancreas
Inhibits gastric acid secretion
Gastric inhibitory peptide (GIP):
Site of secretion
Stimulus
Action
K cells of duodenum and jejunum
Protein, fat, carbs
Stimualtes insulin release
Inhibits gastric acid secretion
Motilin:
Site of secretion
Stimulus
Action
M cells of duodenum and jejunum
Fat, acid, nerve
Stimulates gastric motility, intestinal motility