GI/GU infect Flashcards

1
Q

who woudl you treat for diarrhea

A
  1. Sick immunocompetent patients with bacillary dysentery (frequent scant bloody stools, abdominal pain, tenesmus, fevers), suggestive of Shigella
  2. Recent travel with high fever (≥ 38.5) and/or sepsis
  3. Sick immunocompromised patients
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2
Q

camphylobacter first choice

A

azithro

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3
Q

salmonella enterica typhi /paratyphi tx

A

CTX/Cipro

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4
Q

Shigella tx

A

AZITHRO OR CIPRO OR CEFTRIAXONE

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5
Q

VIBRIO CHOLERA TX

A

DOXYCYCLINE

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6
Q

YERSINIA ENTEROLITICA TX

A

TMP SMX

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7
Q

WHAT’S C DIFF COLONZIATION
do you treat ?

A

positiveC. diff stool test in absence of clinical
syndrome

don’t treat

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8
Q

why is fidaxomicin good

A

less recurrence

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9
Q

when to use PR vancomyicin in cdiff

A

if paralytic ileus or bowel discontinuity

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10
Q

1st c diff relapse tx options

A

Fidaxomicin 200mg PO BID x 10d OR BID x 5d then q2d x 20d

Vancomycin Taper + Pulse

Vancomycin 125mg PO QID x 10d (14d)

Metronidazole 500mg PO TID x 10-14d

Bezlotoxumab 10mg/kg IV x 1

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11
Q

> 2nbd relapse tx options

A

Fidax 200mg PO BID x 10d OR BID x 5d then q2d x 20d

Vancomycin Taper + Pulse

Vanco 125mg PO QID x 10d then Rifaximin 400mg x 20d

Bezlotoxumab 10mg/kg IV x 1

FMT (≥3 episodes)

Oral Vancomycin Suppression

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12
Q

size of intra abdo collection managed with atb alone

A

Collections 3cm or smaller can be attempted to be managed with antibiotics alone

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13
Q

acute prostatitis treatment

A

FQ, tazocin, 3rd gen cephalo

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14
Q

how long do you treat chronic prostatitis?

A
  • 4-6 weeks w/ FQ
  • 8-12 weeks other atb
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15
Q

atb to use for chronic prostatitis

A
  • fq
  • tmp smx
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16
Q

gonorhea
- incubation time
- which type of infection more asymptoamtic
- women vs men : asymptomatic usually?

A
  • 2-7 days
  • rectal & pharynx
  • women
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17
Q

chlam
- subtype of aggresssive chlam

A

LGV

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18
Q

epideididymitis : chlam vs gono

A

chllam»>

19
Q

DGI
- complication sx
- more common in who

A
  • arthritis, dermatitis, endocarditis, meningitis
  • pregnant woman, MSM
20
Q

chlam
- incubation
- asx % in woman and women
- LGV

A
  • 2-6 weeks
  • 50% men , 70% woman
  • more invasive !!!
21
Q

DGI tx

A

ceftriaxone 1-2mg IV/IM DIE x 7 dAYS

22
Q
A
23
Q

LGV TX ?

A

doxycycline 100 mg po BID x 21 days

24
Q
A
24
Q
A
25
Q

TOC gono ?

A

after 2 weeks

26
Q

TOC chlamyd
- how long after
- indication

A
  • 3-4 weeks
  • LGV, unclear compliance, alt regimen, pregnancy
27
Q

pregnancy vs chlamydia tx option

A

azithro

28
Q

argyll robertson pupils specific to which disease ?

A

syphilis

29
Q

primary syphilis presentation and time span

A

3w-90 days
painless chancres, regional LN

30
Q

secondary syphilis and presentation
-?timeline

A

Fever, malaise, rash, alopecia, uveitis, meningitis, LN, hepatitis, arthralgias, condylomata lata
-12w to 6M

31
Q

latent , what is it , and how can you split it

A

latentn syphilis - asymptomatic with positive serology
- early <1 y
- late >1y or unknown

32
Q

tertiary syphilis presentation

A

gummatous
aortitis
late neurosyphilis : tabes dorsalis and general paresis

33
Q

which stage can neurosyphilis occur and manifestations ?

A
  • any !!
  • argyl robertson pupil, meningitis, otitis symptoms, headache, ocular sx, dementia, etc
34
Q

primary , secondary, early latent tx

A
  • pen G 2.4 MU x 1
    ( or doxy x 14 days, ctx x 10 days)
35
Q

late latent, tertiary syphilis

A
  • pen G 2.4 MU weekly x 3
    ( or doxy x 28 days, ctx x 10 days)
36
Q

neuro syphilis tx

A

aqueous penicillin q4 x 14 days
if not –> desensitize or ctx x 10-14 d

37
Q

LP indications for syphilis

A

Neurologic, ocular, or auditory symptoms

Inadequate serologic response to treatment

Tertiary syphilis

(HIV with CD4 < 350 or RPR >1:32 maybe)

38
Q

which syphilis testing is specific to syphilis and persists ?

A

TT

39
Q

which syphilis testing is non specific and released ddduring infection

A

ntt

40
Q

meds for mpox ?

A

self resolve
tecovirimat

41
Q

what ddo you give mpox post exposure /high risk people?

A

imvamune

42
Q
A