GI Drugs

Question 1

H2 Blockers action

Answer 1

block receptors and decreases gastric acid production

Question 2

Examples of H2 blockers

Answer 2

Ranitidine (zantac), famotidine (pepcid), nizatidine (Axid)

Question 3

Safest H2 to use with liver dysfunction

Answer 3

axid

Question 4

when do you give H2 blocker

Answer 4

before meals, one hr after antacids, at bed time

Question 5

PPI ending

Answer 5

prazoles

Question 6

PPI action

Answer 6

decreases acid in stomach

Question 7

PPI indications

Answer 7

peptic and duodenal ulcers, GERD

Question 8

When do you give PPI

Answer 8

before meal

Question 9

Examples of PPI

Answer 9

esomeprazole (nexium), omeprazole (prilosec), pantoprazole (protonix)

Question 10

Muscosal protectant action

Answer 10

coats ulcer to protect from acid

Question 11

example of mucosal protectant

Answer 11

sucralfate (caralfate)

Question 12

interactions with mucosal agents

Answer 12

dilantin, cipro, penicillamines

Question 13

When do you take mucosal agents and what food to eat

Answer 13

before bed on empty stomach, high fiber food

Question 14

example of osmotic laxative

Answer 14

lactulose

Question 15

how does osmotic laxative work

Answer 15

draws water into colon

Question 16

how do emollient stool softners work

Answer 16

water accumulation to lubricate stool

Question 17

example of emollient

Answer 17

colace (docusate)

Question 18

contraindications with laxatives

Answer 18

undiagnosed abdominal pain, inflammatory disorders, spastic colon, bowel obstruction

Question 19

how do antidiarrheals work

Answer 19

decreases motility dont use for more than 2 days

Question 20

examples of antidiarrheals

Answer 20

opiates, somastostatin analog

Question 21

antiemetics action

Answer 21

inhibits chemoreceptor trigger zone and decreases sensitivity of vestibular apparatus

Question 22

examples of antiemetics

Answer 22

hydroxzine (vistaril), promethazine (phernergan), ondasteron (zofran)