GI Drugs Flashcards

1
Q

budesonide (oral capsules)

A

Entocort EC

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2
Q

budesonide (Entocort EC) Strength

A

3 mg

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3
Q

budesonide (Entocort EC) Indication

A

Crohn’s Disease

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4
Q

budesonide (Entocort EC) Category

A

Corticosteroid

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5
Q

budesonide (Entocort EC) Counsel

A

HA, Nausea, Immunosupression, avoid GFJ

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6
Q

dexlansoprazole

A

Dexilant

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7
Q

dexlansoprazole (Dexilant) Strength

A

30mg, 60mg

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8
Q

dexlansoprazole (Dexilant) Indication

A

GERD/Ulcers

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9
Q

dexlansoprazole (Dexilant) Category

A

PPI**

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10
Q

dexlansoprazole (Dexilant) Counsel

A

HA, N/V/D, flatulence, abdominal pain, Take 1/2 hr before meals

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11
Q

H2 Blockers (e.g. rantidine)

A

Zantac

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12
Q

H2 Blockers

A

famotidine (Pepcid), cimetidine (Tagamet), nizatidine (Axid).

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13
Q

H2 Blockers (ranitidine/Zantac) Strength

A

75 [OTC], 150 [OTC and Rx], 300 mg

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14
Q

H2 Blockers (ranitidine/Zantac) Indication

A

GERD/Ulcers

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15
Q

H2 Blockers (ranitidine/Zantac) Category

A

H2 Antagonist*

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15
Q

telaprevir

A

Incivek

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16
Q

H2 Blockers (ranitidine/Zantac) Counsel

A

N/V/D, constipation. Tachyphylaxis (tolerance) can develop after 2 weeks of chronic use

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17
Q

telaprevir (Incivek) Strength

A

375 mg

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18
Q

telaprevir (Incivek) Indication

A

Hepatitis C

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19
Q

telaprevir (Incivek) Category

A

Antiviral/ Protease Inhibitor

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20
Q

telaprevir (Incivek) Counsel

A

Fatigue, Rash, Hyperuricemia, pruritus, N/V/D, Anemia, SJS, Take with food, avoid pregnancy

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21
Q

mesalamine oral capsule & tablet, rectal suspension & suppository

A

Many

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22
Q

Brand names of mesalamine

A

5-ASA - Apriso, Asacol, Canasa, Lialda, Pentasa, Rowasa [rectal suppository] (NOT interchangeable)

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23
Q

mesalamine Strength

A

Many - check formulation

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24
Q

mesalamine Indication

A

Ulcerative Colitis (UC), Ulcerative Proctitis (UP)

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25
Q

mesalamine Category

A

Salicylate

26
Q

mesalamine Counsel

A

N/V/D, HA, abdominal pain, flatulence

27
Q

PPI (e.g. omeprazole capsule)

A

Prilosec

28
Q

PPI (omeprazole/Prilosec) Strength

A

20 mg, 40 mg

29
Q

PPIs

A

lansoprazole (Prevacid), pantoprazole (Protonix), esomeprazole (Nexium), dexlansoprazole (Dexilant, formerly Kapidex),
rabeprazole (Aciphex), omeprazole/sodium bicarbonate (Zegerid)

30
Q

PPI (omeprazole/Prilosec) Indication

A

GERD/Ulcers

31
Q

PPI (omeprazole/Prilosec) Category

A

PPI**

32
Q

PPI (omeprazole/Prilosec) Counsel

A

HA, N/V/D, flatulence, abdominal pain. Take 1/2 hour before meals, many are acid labile

33
Q

ondansetron tablet

A

Zofran

34
Q

ondansetron (Zofran) Strength

A

4 mg, 8 mg

35
Q

ondansetron (Zofran) Indication

A

Nausea

36
Q

ondansetron (Zofran) Category

A

5-HT3 Antagonist, Antiemetic

37
Q

ondansetron (Zofran) Counsel

A

HA, diarrhea, fatigue, dizziness, constipation

38
Q

peginterferon Alfa-2a injection

A

Pegasys

39
Q

peginterferon (Pegasys) Strength

A

180mcg/ml, 180mcg/0.5ml

40
Q

peginterferon (Pegasys) Indication

A

Hepatitis C

41
Q

peginterferon (Pegasys) Category

A

Interferon

42
Q

promethazine HCl

A

Phenergan

43
Q

peginterferon (Pegasys) Counsel

A

HA, fatigue, fever, alopecia, pruritus, N/V, neutropenia, injection site reaction, arthalgia

44
Q

promethazine HCl (Phenergan) Strength

A

12.5 mg, 25 mg, 50 mg

45
Q

promethazine HCl (Phenergan) Indication

A

Nausea, vomiting, motion sickness

46
Q

promethazine HCl (Phenergan) Category

A

Antiemetic

47
Q

promethazine HCl (Phenergan) Counsel

A

Dizziness, drowsiness, orthostatic hypotension, avoid alcohol

48
Q

sevelamer

A

Renvela, RenaGel

49
Q

sevelamer (Renvela, RenaGel) Strength

A

400, 800 mg

50
Q

sevelamer (Renvela, RenaGel) Indication

A

Hyperphosphatemia

51
Q

sevelamer (Renvela, RenaGel) Category

A

Phosphate Binder

52
Q

sevelamer (Renvela, RenaGel) Counsel

A

N/V/D, dyspepsia, flatulence, constipation

53
Q

octreotide

A

Sandostatin LAR

54
Q

octreotide (Sandostatin LAR) Strength

A

IM Inj. 10, 20, 30mg

55
Q

octreotide (Sandostatin LAR) Indication

A

Diarrhea

56
Q

octreotide (Sandostatin LAR) Category

A

Antidiarrheal, Somatostatin Analog

57
Q

Abbreviations

A

Cl- Chan - Chloride Channel; GFJ - GrapeFruit Juice; GERD - GastroEsophogeal Reflux Disease;
IBS - irritable bowel syndrome; PPI - proton pump inhibitor; HA - Headache; N/V/D - Nausea, Vomiting, Diarrhea; UC, UP - Ulcerative Colitis, Ulcerative Proctitis; MOA - Mechanism Of Action;
5HT - 5,HydroxyTryptamine (Serotonin); 5-ASA - 5,Amino Salicylic Acid; Panc Enz Def - Pancreatic Enzymes Deficiency;(Panc Enz: lipase, amylase, protease)

58
Q

octreotide (Sandostatin LAR) Counsel

A

HA, fatigue, hyperglycemia, bradycardia, chest pain, pruritus, abdominal pain, N/V/D

59
Q

Counseling

A
***While the H2 Blockers (and PPIs)
have similar properties, they are not
interchangeable and each one offers a
different array of drug properties and interactions.
You may think of them as a class of
medications but do NOT assume that if there
is no drug interaction with ranitidine (Zantac)
that there won't be an interaction if your patient
switches to cimetidine (Tagamet)***
60
Q

Counseling 2

A

H2 Blockers are antihistamines, don’t confuse them with allergy meds e.g. diphenhydramine (Benadryl), loratadine (Claritin) which are H1 blockers

62
Q

Brand names of pancrelipase

A

Creon, Zenpep, Pancreaze (others include: Dygase, Ku-Zyme, Lipram, Palcaps, Pancrease, Pancrecarb, Pancron,
Pangestyme, Panocaps, Panokase, Plaretase, Ultracaps, Ultrase, Viokase, Cotazym S, et al these are NOT interchangeable)

63
Q

Note

A

budesonide also comes as an inhaler (Pulmicort) for asthma.