GI Drugs Flashcards

1
Q

budesonide (oral capsules)

A

Entocort EC

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2
Q

budesonide (Entocort EC) Strength

A

3 mg

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3
Q

budesonide (Entocort EC) Indication

A

Crohn’s Disease

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4
Q

budesonide (Entocort EC) Category

A

Corticosteroid

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5
Q

budesonide (Entocort EC) Counsel

A

HA, Nausea, Immunosupression, avoid GFJ

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6
Q

dexlansoprazole

A

Dexilant

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7
Q

dexlansoprazole (Dexilant) Strength

A

30mg, 60mg

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8
Q

dexlansoprazole (Dexilant) Indication

A

GERD/Ulcers

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9
Q

dexlansoprazole (Dexilant) Category

A

PPI**

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10
Q

dexlansoprazole (Dexilant) Counsel

A

HA, N/V/D, flatulence, abdominal pain, Take 1/2 hr before meals

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11
Q

H2 Blockers (e.g. rantidine)

A

Zantac

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12
Q

H2 Blockers

A

famotidine (Pepcid), cimetidine (Tagamet), nizatidine (Axid).

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13
Q

H2 Blockers (ranitidine/Zantac) Strength

A

75 [OTC], 150 [OTC and Rx], 300 mg

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14
Q

H2 Blockers (ranitidine/Zantac) Indication

A

GERD/Ulcers

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15
Q

H2 Blockers (ranitidine/Zantac) Category

A

H2 Antagonist*

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15
Q

telaprevir

A

Incivek

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16
Q

H2 Blockers (ranitidine/Zantac) Counsel

A

N/V/D, constipation. Tachyphylaxis (tolerance) can develop after 2 weeks of chronic use

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17
Q

telaprevir (Incivek) Strength

A

375 mg

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18
Q

telaprevir (Incivek) Indication

A

Hepatitis C

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19
Q

telaprevir (Incivek) Category

A

Antiviral/ Protease Inhibitor

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20
Q

telaprevir (Incivek) Counsel

A

Fatigue, Rash, Hyperuricemia, pruritus, N/V/D, Anemia, SJS, Take with food, avoid pregnancy

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21
Q

mesalamine oral capsule & tablet, rectal suspension & suppository

A

Many

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22
Q

Brand names of mesalamine

A

5-ASA - Apriso, Asacol, Canasa, Lialda, Pentasa, Rowasa [rectal suppository] (NOT interchangeable)

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23
Q

mesalamine Strength

A

Many - check formulation

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24
mesalamine Indication
Ulcerative Colitis (UC), Ulcerative Proctitis (UP)
25
mesalamine Category
Salicylate
26
mesalamine Counsel
N/V/D, HA, abdominal pain, flatulence
27
PPI (e.g. omeprazole capsule)
Prilosec
28
PPI (omeprazole/Prilosec) Strength
20 mg, 40 mg
29
PPIs
lansoprazole (Prevacid), pantoprazole (Protonix), esomeprazole (Nexium), dexlansoprazole (Dexilant, formerly Kapidex), rabeprazole (Aciphex), omeprazole/sodium bicarbonate (Zegerid)
30
PPI (omeprazole/Prilosec) Indication
GERD/Ulcers
31
PPI (omeprazole/Prilosec) Category
PPI**
32
PPI (omeprazole/Prilosec) Counsel
HA, N/V/D, flatulence, abdominal pain. Take 1/2 hour before meals, many are acid labile
33
ondansetron tablet
Zofran
34
ondansetron (Zofran) Strength
4 mg, 8 mg
35
ondansetron (Zofran) Indication
Nausea
36
ondansetron (Zofran) Category
5-HT3 Antagonist, Antiemetic
37
ondansetron (Zofran) Counsel
HA, diarrhea, fatigue, dizziness, constipation
38
peginterferon Alfa-2a injection
Pegasys
39
peginterferon (Pegasys) Strength
180mcg/ml, 180mcg/0.5ml
40
peginterferon (Pegasys) Indication
Hepatitis C
41
peginterferon (Pegasys) Category
Interferon
42
promethazine HCl
Phenergan
43
peginterferon (Pegasys) Counsel
HA, fatigue, fever, alopecia, pruritus, N/V, neutropenia, injection site reaction, arthalgia
44
promethazine HCl (Phenergan) Strength
12.5 mg, 25 mg, 50 mg
45
promethazine HCl (Phenergan) Indication
Nausea, vomiting, motion sickness
46
promethazine HCl (Phenergan) Category
Antiemetic
47
promethazine HCl (Phenergan) Counsel
Dizziness, drowsiness, orthostatic hypotension, avoid alcohol
48
sevelamer
Renvela, RenaGel
49
sevelamer (Renvela, RenaGel) Strength
400, 800 mg
50
sevelamer (Renvela, RenaGel) Indication
Hyperphosphatemia
51
sevelamer (Renvela, RenaGel) Category
Phosphate Binder
52
sevelamer (Renvela, RenaGel) Counsel
N/V/D, dyspepsia, flatulence, constipation
53
octreotide
Sandostatin LAR
54
octreotide (Sandostatin LAR) Strength
IM Inj. 10, 20, 30mg
55
octreotide (Sandostatin LAR) Indication
Diarrhea
56
octreotide (Sandostatin LAR) Category
Antidiarrheal, Somatostatin Analog
57
Abbreviations
Cl- Chan - Chloride Channel; GFJ - GrapeFruit Juice; GERD - GastroEsophogeal Reflux Disease; IBS - irritable bowel syndrome; PPI - proton pump inhibitor; HA - Headache; N/V/D - Nausea, Vomiting, Diarrhea; UC, UP - Ulcerative Colitis, Ulcerative Proctitis; MOA - Mechanism Of Action; 5HT - 5,HydroxyTryptamine (Serotonin); 5-ASA - 5,Amino Salicylic Acid; Panc Enz Def - Pancreatic Enzymes Deficiency;(Panc Enz: lipase, amylase, protease)
58
octreotide (Sandostatin LAR) Counsel
HA, fatigue, hyperglycemia, bradycardia, chest pain, pruritus, abdominal pain, N/V/D
59
Counseling
``` ***While the H2 Blockers (and PPIs) have similar properties, they are not interchangeable and each one offers a different array of drug properties and interactions. You may think of them as a class of medications but do NOT assume that if there is no drug interaction with ranitidine (Zantac) that there won't be an interaction if your patient switches to cimetidine (Tagamet)*** ```
60
Counseling 2
H2 Blockers are antihistamines, don't confuse them with allergy meds e.g. diphenhydramine (Benadryl), loratadine (Claritin) which are H1 blockers
62
Brand names of pancrelipase
Creon, Zenpep, Pancreaze (others include: Dygase, Ku-Zyme, Lipram, Palcaps, Pancrease, Pancrecarb, Pancron, Pangestyme, Panocaps, Panokase, Plaretase, Ultracaps, Ultrase, Viokase, Cotazym S, et al these are NOT interchangeable)
63
Note
budesonide also comes as an inhaler (Pulmicort) for asthma.