GI drugs

Question 1

Which prodrug requires acidic ph for its activation?

Answer 1

Omelrazole (inactive at neutral ph)

Question 2

Nucleus tractus solitarius (NTS) & CTZ express which receptors?

Answer 2

M1, H1, Cannabinoid1, Nk1, D2, 5HT3 u-opioid

Question 3

Antiemetic used in motion sickness?

Answer 3

Hyoscine, Dicyclomine

Question 4

Which purgative drug is preferred in drug poisoning?

Answer 4

Saline purgatives

Question 5

Purgative preferred in atonic functional constipation

Answer 5

1. Fluids, exercise, reassurance. 2. Bulk forming agents or osmotic purgative (lactulose/ Mg(OH)2). 3. Bisacodyl or Senna

Question 6

Purgatives in spastic constipation

Answer 6

Isphagulla

Question 7

Purgative for bedridden patients

Answer 7

Enema to treat and Bulk forming agents for prophylaxis

Question 8

Prucalopride is

Answer 8

5HT4 agonist used as a laxative

Question 9

Antimicrobial used in cholera

Answer 9

Tetracycline, cotrimoxazole, norfloxacin, cipro.

Question 10

Rifaximin used in

Answer 10

Travellers diarrhoea

Question 11

Pseudomembranous enterocolitis doc

Answer 11

Metronidazole/ Vancomycin

Question 12

Doc for constipation during pregnancy

Answer 12

Lactulose? Not sure

Question 13

Doc for stress ulcers

Answer 13

Ranitidine

Question 14

Least potent ppi

Answer 14

Pantoprazole

Question 15

Ppi having interaction with clopidogrel

Answer 15

Omeprzole

Question 16

H2 blocker having maximum drug interactions

Answer 16

Cimetidine

Question 17

Black coloured stools,tongue & dentures is side effect of which ulcer protective

Answer 17

CBS

Question 18

Active metabolite of ppi

Answer 18

Sulfenamide

Question 19

Most potent ppi

Answer 19

Iloprazole

Question 20

Encephalopathy is a S/E of

Answer 20

Al3+ salts

Osteoporosis also

Question 21

Milk alkali syndrome caused by

Answer 21

CaCO3 antacid