GI Disorders Flashcards
How much fluid does the GI tract produce per day?
How much fluid is not absorbed?
9L
only 100 ml
Where does parasympathetic stimulation from the spinal cord originate?
Medulla
S2 - S4
What occurs when you distend the bowels?
What drug do you give to correct the effects?
Bradycardia → Vasodilation → Hypotension
Glycopyrrolate
What secretions are alkaline from greatest to least?
saliva
gastric fluid
bile
pancreatic fluid
small intestine
colon
pancreatic fluid
colon
bile
small intestine
saliva
gastric fluid
High risk of aspiration pneumonitis if volume > ____ ml and pH < _____.
25ml
2.5
What increases risk of aspiration pneumonitis? (5)
Pregnancy
GERD
Myasthenia gravis
Stroke
ALS (paralysis of throat)
How do you prevent aspiration pneumonitis? (5)
Minimize intake
Increase gastric emptying
Reduce gastric volume/acidity
RSI
Proseal LMA
What are fasting guidelines for clear liquids for:
children
adults
2 hours
3 hours
What does the ASA recommend for fasting with:
breast milk
formula and light meals
4 hours
6 hours
What are physiologic states that decrease GI emptying and increase risk of aspiration? (3)
Pregnancy
Bowel obstruction
Diabetes (peritonitis)
What causes ileus after surgery? (6)
Pain
Sympathetic hyperactivity
Opioids
Electrolyte imbalances
Immobility
Intestinal wall swelling
I POISE
How long is the esophagus?
8 inches
What prevents aspiration of gastric contents into the lungs and the swallowing of air?
upper esophageal sphincter
What do most anesthetic agents do to upper esophageal sphincter tone?
What occurs as a result?
decrease, except ketamine
increase risk of aspiration
What is a diverticulum of the mucosa of the pharynx just above the cricopharyngeal muscle?
What is contraindicated?
Zenker’s diverticulum
NO CRICOID pressure
What is depicted?
Zenker’s Diverticulum
_____ in lower esophageal pressure leads to gastroesophageal reflux.
Decrease
What is the resting pressure in the lower esophageal sphincter?
When does GERD become an issue?
30 mmHg
<10 mmHg
What is barrier pressure?
What does cricoid pressure do to barrier pressure?
What does Sux do to these pressures?
Difference between gastric pressure and LES pressure.
Decreases thus leading to decreased LES tone since there is no change in gastric pressure.
Increases gastric pressure leading to increase in LES tone.
What anesthetic related drugs decrease LES tone? (4)
Inhaled agents
Opioids
Anticholinergics (glyco)
Propofol
What other drugs decrease LES tone? (4)
Beta-blockers
Ganglion blockers
Antidepressants
Glucagon
What drugs increase LES tone? (7)
Anticholinesterases (Neostigmine)
ACh
Alpha-adrenergic agonists
Antacids
Cholinergics
Metoclopramide
Metoprolol
What hormones, etc. increase LES tone? (3)
Serotonin
Histamine
Pancreatic polypeptide
What drugs do not change LES tone? (3)
H2-receptor antagonists (cimetidine)
Nondepolarizing muscle relaxants
Propranolol
What is esophagogastroduodenoscopies useful for? (6)
Banding
Biopsy
GERD
Ulcers
Dilation
Ultrasound
What is heartburn caused by?
An incompletely closed LES allowing acid to reflux into the esophagus.
What is the regular reflux of stomach acid irritating the esophagus which may lead to malignancy?
Barrett’s Esophagus
What is depicted?
Barrett’s esophagus
What is achalasia?
LES does not relax and results with difficulty swallowing and regurgitation of food.