GI Diseases and Surgery Flashcards

1
Q

Why are camelids termed pseudoruminants?

A

They rely on forestomach bacterial and protozoal fermentation for breakdown of plant nutrients, however there are distinct differences from the ruminant

C1 is most analogous to the rumen but lacks papillae that are present in the rumen

C2 is analogous to the reticulum and omasum, sortinf feed particles primarily by size

C3 is analogous the the abomasum or more like the monogastric stomach; proximal 80% is not acid secreting, distal 20% is

All 3 compartments have capacity for secretion and absorption

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2
Q

Main difference in C1 motility compared to the rumen

A

C1 motility progresses from cranial to caudal, vs in the rumen where it is caudal to cranial

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3
Q

Location and function of C1 saccules

A

Caudal and ventral C1, thought to aid in micro-fermentation and be bicarbonate secreting

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4
Q

Unique feature of the camelid duodenum

A

Has a prominent ampulla immediately aboral to the pylorus; can be mistaken for pyloric stricture or duodenal diverticulum

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5
Q

Do camelids have a gall bladder?

A

NO - like the horse

Ruminants do

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6
Q

Main difference in omentum vs ruminants

A

Much less prominant than ruminants. In camelids, it does not attach to the dorsal body wall

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7
Q

Clinical signs of colic in camelids

A

Groaning, bruxism, getting up and down, refusing to stand, rolling, kicking or looking at the belly, peculiar stance, kyphosis, depression, pyrexia, anorexia, tachycardia, tachypneic, tenesmus, decreased fecal output, tense or painful abdomen, distended abdomen, pollakiuria, C1 atony, and regurgitation

Tends to be more subtle like cows vs overt like horses

Clinical signs of forestomach lesions tend to be the most subtle, more marked w

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8
Q

Why is there not the same tendency toward hypochloraemic metabolic alkalosis commonly seen in cattle w GI (esp abomasal) issues

A

Camelids have a higher capacity to absorb water and chloride via C1 than ruminants do from the rumen

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9
Q

Site for abdominocentesis in camelids

A

Ideally under US guidance

If blind, 1cm dorsal and 3cm caudal to the costochondral junction of the last rib in alpacas (2cm dorsal and 5cm caudal in llamas) on the RHS

Approx a hands breadth behind the last rib

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10
Q

Most appropriate surgical approach(es) for C1 lesions

A

Left PLF (as for rumenotomy in cattle/sheep)

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11
Q

Most appropriate surgical approach(es) for C2 and C3 lesions

A

Right PLF or ventral midline

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12
Q

Most appropriate surgical approach(es) for large and small intestinal lesions

A

Ventral midline or right PLF

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13
Q

Most appropriate surgical approach(es) for proximal duodenal lesions

A

Right paracostal approach

Common condition would be obstruction by trichophytobezoar - can be removed by duodenotomy or repulsion and C3 gastrotomy

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14
Q

List reported surgical indications for forestomach disease (C1-3)

A

C1 FB

Trichophytobezoar (various locations, usually C3 or proximal duodenum)

C3 ulceration

GI rupture

Neoplasia

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15
Q

Small intestinal surgical lesions

A

Intraluminal obstruction (trichophytobezoar)

Intussusception

Torsion

EFE ( is reported)

Neoplasia

FB

Adhesions

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16
Q

Describe the right paracostal approach

A

LLR. Approx 14cm skin incision parallel and immediately caudal to the last rib

Incise EAO, IAO and transversus (plus peritoneum)

C3 and proximal duodenum are easily accessible from this approach

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17
Q

Suggested small intestinal enterotomy closure (suture size and patterns)

A

3-0 or 4-0 PDS or polyglactin in full thickness simple continuous with Cushing oversew

Cushing pattern decreased lumen size less than Lembert

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18
Q

Parasite that may be assoc with iliocaecocolic intussusceptions

A

Eimeria spp - coccidiosis

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19
Q

Large intestinal lesions which may require surgery

A

Impactions (see diagram, relative narrowing of the ascending colon)

Torsion of the spiral colon

Diaphragmiatic herniation

GI rupture

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20
Q

Possible complications after abdo surgery

A

Adhesions

Septicaemia

Septic peritonits

Ileus

Recurrence of pica (tricophytobezoars)

Anastomotic complications

Incisional complications

21
Q

Colic Ddx

22
Q

Indications for GI surgery

A

Continuous intractible pain

Persistent low grade discomfort despite tx

Abnormal rectal findings

Abnormal PTap - TNC >5x10’9, >80% neuts, TP>30g/L

Failure to pass faeces for >24hrs (indicative of intestinal obstruction)

Failure to urinate >6-8hr (urinary obstruction)

Hypochloraemic metabolic alkalosis - indicates upper GI obstruction (less consistent than in ruminants)

Dystocia or uterine torsion - left flank for caesar

23
Q

Most suitable approach for uterine surgery

A

Left flank/PLF

24
Q

Management options for tooth root abscessation

A

Mandibular teeth most commonly affected

6 weeks ABx - florfenicol at a dose of 20 mg/kg every other day

Extraction (oral or repulsion?)

25
Dental formula of SACs? And Camels?
SACs - deciduous - I 1/3, C 1/1, PM 2-3/1-2 Permanent - I 1/3, C 1/1, PM 1-2/1-2, M 3/3 Camels - deciduous - I 1/3, C 1/1 PM 3/2 Permanent I 1/3, C 1/1, PM 3/2, M 3/3 All have 3 upper and lower molars on each side like ruminants & horses Have a single upper incisor (vs ruminants w 0) which sits behind the lower corner incisor and looks like a canine. In addition to the normal upper canine looks like they have 4 upper canines - also makes camels bites v dangerous as can open mouths v wide (SACs can't) Camels have more premolars (3 upper 2 lower) than SACs (1-2 upper and lower), but the first premolar of camels has migrated forward and become caniniform - so the camel appears to have 3 upper and 2 lower canines on each side. Vs sheep/goats/cattle that appear to have no upper and 4 lower incisors, as the lower canine has migrated forward and appears incisor like
26
C 1 mucosa
nonglandular mucosa of C1 is keratinised stratified squamous epithelium - non papillated (vs papillae found in rumen) Ventral surfaces of both the cranial and caudal sacs of C-1 contain glandular saccules (rumen has not glandular tissue)
27
C2 mucosa
Mucosal surface of C2 is glandular except for a small area on the lesser curvature that constitutes the oesophageal or ventricular groove The glandular area is subdivided by a series of intersecting crests that produce a retiform pattern and is covered by a papillated glandular mucosa; this retiform pattern is not analogous to the pattern seen in the reticulum of ruminants
28
Main differences between camelid & ruminant stomachs
29
C3 mucosa (splint into 5ths)
C3- mucosa is entirely glandular; 3 pattern areas and 2 types of mucosa First 1/5 - lesser curvature - retiform pattern with short crests and shallow depressions First 1/5 - greater curvature - nonpermanent folds Middle 3/5 = permanent longitudinal pleats (approximately 50) Proximal 4/5 = mucinous glandular tissue Final 1/5 = true gastric glands. The mucosa is reddish-brown, in contrast to the lighter pink of the proximal four-fifths. The wall of this area is thickened and the mucosal surface smooth. Digestive enzymes and acid are secreted by these glands pH in the cranial segment of C3 is 6.5, decreasing to 2 in the terminal 1/5
30
Omentum
Relatively small vs sheep and cows In ruminants, the omental sling covers much of the intestine - no omental sling in camelids The greater omentum is attached along both the lesser and greater curvatures of C-2 and C-3 and along the right surface of C-1 The epiploic foramen enters the sac formed by the greater omentum ventral to the liver, near the entrance of the post cava into the liver (EFE is reported in a llama)
31
Features of large intestinal anatomy
Similar to ruminants - ## Footnote Caecum is approx on midline and directed caudally toward the pelvic inlet - 10cm long and 5cm diameter Colon similar to the bovine - ascending colon begins as a proximal loop that courses cranially and ventrally to enter the spiral loop The most proximal loop of the ascending colon is loosely attached by a mesentery to the more compact spiral colon. There are 5.5 centripetal coils (including the proximal loop) and 4.5 centrifugal coils. There are only 2 coils in bovines and 3 in ovines Diameter narrows from 5cm at its beginning to 2cm within the first centripetal coil of the spiral loop, making the spiral colon the primary site of faecolith impaction in camelids
32
4 broad mechanisms of diarrhoea
1. Osmotic - eg epsom salts or malabsorption 2. Secretory - eg enterotoxigenic E coli - toxins rx in prolonged opening of chloride chanels rx in uncontrolled water secretion. Secretion outstrips absorption 3. Altered mucosal permeability - epithelial damage dt infection/inflammation; poor efficiency of absorption 4. Motility dysfuncion - accellarated transit time decreasing capacity for absorption
33
Treatment considerations for oesophageal obstruction in camelids.
Less common vs equines / bovines - more voluntary control of the oesophagus Assoc. w ingestion of apples. Perii-oesophageal haematoma formation also can cause external compression CSs incl retching, coughing, dysphagia, head shaking, salivation, nasal discharge, anxiety, and, if a blockage is prolonged, dehydration & Aspiration pneumonia a common sequalae May not be able to palpate cervical obstruction as you can in the horse as the oesophagus is deeper in camelids and obscured by the ventral tubercle of the cervical vertebral TPs Dx - attempted NGT passage, contrast rads Tx - spasmolyitcs (atropine, regelen) to relax the oesophageal musculature, analgesics, followed by passage of NGT t try and push the obstruction aborally May need GA dt likihood of stimulating regurgitation Complete obstruction will prevent eructation - subsequent bloat may req needle decompression via left PLF
34
Features of gastric/grain overload in camelids
Uncommon as unlikely to consume large quantities of grain ## Footnote Overingestion of highly fermentable carbs leads to lactic acidosis, dehydration, and depression Fermentation leads to production of acetate, propionate, butyrate -\> with overload - high lactic acid & other long chain faty acids are produced Lactic, formic, valeric, and succinic acids change the osmolarity of C-1, resulting in fluid being drawn in from the circulatory system and other tissues. Thirst also results in accumulation of excessive water in C-1. The pH of C-1 may drop to 4; gastric stasis and destruction of the normal C-1 microflora Rx in profuse d+ and gastritis Liver abscessation ay occur 2ary to hepatic portal bacteraemia CSs are consistent w endoxaemia may appear upto 36hrs post ingestion CSs incl weakness, incoordination, depression, anorexia, C-1 atony, colic (grunting, grind- ing teeth), abdominal distention, dehydration, a foetid diarrhoea, and recumbency Death in 12-48hrs without tx Hx is vital in dx. Other indicators are C1 ingesta pH - shouldn’t be less than 5.5 as in cow rumen Tx - antacids alone may be sufficient in mild case 1g/kg magnesium OH or CO3 may be given in 3L (adult llama). 0.5g/kg should be used if the stomach has been emptied prior to administration Also provide thiamine HCl, IV fluids, antibiotics, and flunixin meglumine Gastrotomy to remove the grain is indicated in more valuable animals
35
Normal and abnormal peritoneal fluid values Which peritoneal fluid parameter(s) can give dx of ruptured bladder?
See table Potassium is most useful in suspected bladder rupture. Createnine \> double in horses not mentioned in small ruminants or camelids
36
Types of GI concretions in camelids
1) mineral stones (concretions, gastroliths, enteroliths), (2) compacted plant fibre balls (phytobezoars, fecaliths, impaction) (3) hair balls (trichobezoars, zoo-trichobezoars). A fourth type may be a combination of one or more of the other three In other species, mineral component typically magnesium ammonium phosphate (struvite) Saccules of C1 are a common location for concretions to form - these cause no known impairment in C1 function. Common incidental PM or rad finding Other concretions at other locations may cause obstruction, perforation, or ulceration C3 tricophytobezoars pathologic - obstruction, ultimate death. Also can affect small intestine, large (spiral) and small colon
37
Ddx for haemoabdomen
* rupture liver/spleen dt trauma * Cranial uterine aa is in the freely moveable broad ligament & may be subject to trauma late in pregnancy. * Umbilical arteries may rupture too close to body wall in neonates & retract into abdomen * Spermatic cord under excessive tension during transection, can retract into the abdomen
38
Surgical approaches to the camelid abdomen
1) Ventral midline; can be cranial to umbilicus or caudal to it a) Cranial to umbilicus, layers incised are: skin, SQ areolar tissue, a single layer of fascia comprised of the aponeuroses of the abdominal muscles, deep abdominal fat, and the peritoneum. Closure: peritoneum, fascia, and skin b) Caudal to the umbilicus, will incise skin, subcutaneous tissue, cutaneous trunci muscle, superficial fascia (aponeuroses of the external and internal abdominal oblique muscles), deep fascia (thin aponeurosis of the transversus abdominis muscle), deep abdominal fat, and peritoneum. Lateral to midline the 2 facsias are separated by the rectus abdominis. All other texts describe this as linea rather than separate layers of int and ext sheaths. NB in camelids, there is deep abdominal fat either side of midline - another reason for strict adherence to the midline. Closure: ensure inclusion of all the fascial layers into one or more suture layers. Recommend cruciate (figure-8) pattern w 5metric vicryll for linea/fascial layers. Dehiscence is more common with approaches caudal to the umbilicus 2) Mid-High Flank (PLF) Approach; recommended for approaches to C1 on the left hind side (like rumenotomy in a cow). Vertical incision midway between TC & last rib 6-8cm ventral to lumbar TPs. Recommend grid technique. Closure: peritoneum w simple or continuous pattern. If a grid incision was made, the muscle layers may be closed w simple interrupted sutures. If the muscle masses were incised, they should be accurately apposed and the outer muscle fascial layer included to provide more strength for the suture to optimise healing 3) Left oblique (not described as this name but most analogous to this in a cow) - Used for OVH and abdominal crypts. Begins 6-10cm to the tuber coxa running diagonally ventrally and cranially. Layers incised are skin, SQ, abdominal tunic, fibers of the internal abdominal oblique muscle (blunt dissection), aponeurosis of the transversus abdominis muscle, and peritoneum. Close as for PLF approach 4) Parainguinal - For OVH. Done in lateral. 10-15cm incision made 8cm cranial and dorsal to the inguinal canal (ext ing ring). Incise skin, sq, internal abdominal oblique muscle, which is blunt dissected in the direction of the long axis of the muscle fibres. The transversus abdominis muscle and peritoneum are penetrated in the plane of the muscle fibres 5) Right paracostal (not mentioned here but required for access to C3 and duodenum for FB/phytotrichobezoars which are not uncommon - add in when encountered)
39
List the most appropriate approach(es) to the abdomen for tx of a) C1 lesions b) C2 or C3 lesions c) Duodenal obstruction (trichophytobezoar) d) Small intestine (other than duodenum) e) Large intestine
a) C1 lesions - left PLF b) C2 or C3 lesions - right PLF or ventral midline c) Duodenal obstruction (trichophytobezoar) - right paracostal d) Small intestine (other than duodenum) - ventral midline or right PLF e) Large intestine - ventral midline & right PLF Ie C1 best accessed via left PLF. Duodenum right paracostal then remainder of forestomache, SI and LI either right PLF or ventral midline
40
Ddx for lesions of the forestomaches
* C1 FB * Trichophytobezoars * C3 gastric ulcers * Neoplasia * GI rupture (2ary to ab wall trauma) *
41
Ddx for SI lesions in camelids
* Intraluminal obstruction (eg trichophytobezoar - more common in duodenum & can either be removed via duodenotomy or replusion & C3 gastrotomy. Less common in jejunum & have worse px) * Intussusception (iliocaecocolic intussusceptions may be assoc w Eimera spp) * Torsion * FB * EFE (rare but reported) * Neoplasia * Umbilical abscessses
42
Recommendations for small intestinal enterotomy closure in camelids
Simialr vs other spp but generally 2 layer Full thickness simple cont with Cushing or Lembert oversew. No diff in bursting stregnth but tend to get less reduction in lumen diameter w Cushing vs Lembert PDS generally higher bursting strength vs PG910 - but all above clinically relevant levels so unlikely significant 3-0 or 4-0 suture recommended.
43
Ddx for surgical lesions of the large intestine in camelids
* Impactions (common in caecum/ascending colon) * Torsion of spiral colon * Adhesions * Diaphragmatic hernia (few reports, couldn't close, did well but recurred) * Rectal tears (caudal ventral midline or trans-anal approach)
44
What % of C3 mucosa is glandular
20% - the distal 1/5 is HCl secreting Distinct line of separation between glandular & non-glandular mucosa, with no anatomical separation, like the margo in horses
45
Teeth most commonly affected by apical infection
Mandibular \>maxillary Premolars/molars \> incisors/canines Usually affect camelids 2-5yrs - coincides with age of erruption of cheek teeth; softer gums more likely to be penetrated w feed material
46
Indications for canine removal in llamas
Prevent severe injury with intermale aggression Tooth root infection (poss iatrogenic after trimming)
47
Clinical signs of apical infection
As in other spp - more commonly affects mandibulars - so see mandibular pain/swelling, +/- draining tracts. Peri-apical lysis/sclerosis as in other spp
48
Technique for canine removal
* Fusiform gingival incision around affected tooth extending to mandibule * 2nd incision made directly over the tooth root, curving caudad, in the direction of roots long axis. * Periosteal elevator to reflect gingiva & periosteum from lateral surface of mandible, then similar elevation medially, extending 1/8" from gum–tooth margin. * Segment of bone on the lateral side of the tooth is then removed +/- prior periosteal elevation. Use of a chisel on the lingual side of the tooth facilitates its removal. As bone is removed, the tooth is grasped periodically & moved side-to-side to ascertain when it is ready for extraction. * This facilitates extraction without risking fracture of the mandible. * Alveolus curetted, to remove all diseased bone associated with the root abscess, debris flushed & gingiva is apposed over the empty socket w. 2-0 absorbable, monofilament
49
Technique for molar extraction
* Straight incision directly over longitudinal axis of the tooth. Optionally can reflect periosteum * Bone lateral to the tooth is removed, but bone immediately ventral to the tooth is preserved. Tooth should be freed of bone at its rostral and caudal surfaces using a chisel. * Dental punch is placed on tooth root; gentle tapping seats it into the root of the tooth. Have fingertips over the crown & guide the punch with the other hand. * Assistant then delivers blows to the punch. Feel vibrations of the blows transmitted through the tooth to his fingertips. Occasionally, punch has to be redirected. * Tooth gradually loosens * Alt: hole can be made over the affected roots with a trephine or Hall air drill. * When a single root of a cheek tooth is abscessed, tooth may be split & only the crown associated w infected root removed; so can save much of the occlusal surface * Following repulsion of the tooth, any small fragments of bone or teeth are removed. The alveolus is curetted and is flushed. * Ventral half of the incision is left open for drainage of the alveolus. Upper half is closed with SI nonabsorbable sutures