GI Diseases Flashcards

1
Q

What are the indications for barium swallow?

A
  • Dysphagia
  • Non cardiac chest pain (GERD, esophageal spasm, corkscrew)
  • Painful swallowing (odynophagia)
  • Swallowing abnormalities
  • GE reflux
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2
Q

What are barium swallow contraindications?

A
  • Evidence of bowel obstruction /severe constipation
  • Perforated viscus
  • Unstable vital signs
  • Unable to co-operate with swallowing / disoriented
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3
Q

What is Achalasia? What causes it? What will you see on barium swallow?

A
  • Increased LES pressure
  • Diminished to absent peristalsis in the distal portion of the esophagus composed of smooth muscle
  • Lack of a coordinated LES relaxation in response to swallowing.
  • Bird’s Beak Sign-AKA Rat-tail Sign
  • Irregularly marginated tapering of esophagus in achalasia
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4
Q

What can you see with a barium swallow?

A
  • Stricture/growth
  • Esophageal carcinoma with ulcerations (sharp right angle junction with esophageal wall)
  • Esophageal varices (evidence of portal HTN)
  • Esophageal motility disorders
  • Diverticula
  • Extrinsic compression (mediastinal tumor)
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5
Q

What are the esophageal motility disorders?

A
  • Scleroderma

- Esophageal spasm

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6
Q

What are the types of esophageal diverticula?

A
  • Zenkers: cricopharyngeus muscle

- Epiphrenic: lower esophagus just above diaphragm

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7
Q

EGD gives you a good view of what?

A

esophagus, stomach, and proximal duodenum.

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8
Q

Colonoscopy gives you a good view of what?

A

entire colon and rectum, frequently the terminal ileum

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9
Q

What are common therapeutic endoscopic procedures?

A
  • Dilation of strictures
  • Removal of foreign bodies
  • Polypectomy
  • Endoscopic therapy of intestinal metaplasia
  • Treatment of GI bleeding with injection, banding, coagulation, sclerotherapy
  • Stent placement
  • Gastrostomy
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10
Q

First thing you note about a poly?

A
  • Pedunculated (not as bad, has stalk)

- Sessile (not good, leads to cancer)

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11
Q

Length of metaplasia?

A

3 cm

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12
Q

What diseases cause hyperacidity?

A
  • Duodenal ulcer
  • Gastric cell hyperplasia
  • Carcinoid tumors
  • ZE syndrome
  • Multiple endocrine neoplasia
  • Basophilic leukemia
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13
Q

What diseases cause hypoacidity?

A
  • Gastritis
  • Gastric ulcer
  • Gastric carcinoma
  • Pernicious anemia
  • Partial gastrectomy
  • Chronic iron deficiency anemia
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14
Q

Definitive test for H. Pylori?

A

biopsy

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15
Q

What does H pylori secrete?

A

Urease, so test with urea breath test after 1 month of treatment

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16
Q

How does urea breath test work?

A

The ability of H. pylori to convert urea to ammonia and carbon dioxide. It is the preferred non-invasive choice for detecting H pylori before & after treatment

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17
Q

What is flexible sigmoidoscopy used to view? What interventions?

A

Rectum, sigmoid, and a variable length of more proximal colon.

Biopsy, hemostasis, hemorrhoidal banding, and stent placement

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18
Q

What occurs with Endoscopic retrograde cholangiopancreatography

A

The biliary and pancreatic ductal systems are cannulated and opacified with contrast

19
Q

What can you do while performing a ERCP?

A

Brush cytology, biopsy, intraductal ultrasound (US), cholangioscopy, and pancreatoscopy.

20
Q

What therapeutic maneuvers can be done during ERCP?

A

Endoscopic sphincterotomy +/- stent placement, removal of choledocholithiasis

21
Q

What is another way to visualize the GI tract?

A

Video capsule endoscopy

22
Q

What are the indications for endoscopy?

A
  • If a change in management is probable based on results of endoscopy.
  • After an empirical trial of therapy for a suspected benign digestive disorder has been unsuccessful.
  • As the initial method of evaluation as an alternative to radiographic studies.
  • When a primary therapeutic procedure is contemplated
23
Q

What is a contraindication for endoscopy?

A
  • Perforated viscus is known or suspected
24
Q

How do you treat suspected variceal hemorrhage?

A
  • IV Octreotide
  • Broad spectrum ABX
  • Nonselective BBlockers
25
How do you treat vatical hemorrhages with the EGD? What if it keeps bleeding?
Variceal ligation banding If rebleeding consider transjugular intrahepatic portosystemic shunt (TIPS)
26
How do you treat peptic ulcer bleeding?
Endoscopic therapy with epi and either thermocoagulation or clips
27
How do you treat AV malformations or Mallory-Weiss tears?
Endoscopic therapy with epi and either thermocoagulation or clips
28
First step with hemodynamic instability lower GI bleeding patient? What if they are stable?
Upper endoscopy (rule out upper GI) then colonoscopy Stable: if less than 40 do flexible sigmoidoscopy, if more than 40 colonoscopy
29
What does amylase do?
- only digestive enzyme from pancreas secreted in active form. - Functions at pH 7 - Hydrolyzes stretch and glycogen to glucose, maltose, maltotriose, and dextrins - Range: 50 - 120 U/L
30
Is amylase only in pancreas?
No
31
What is lipase?
pH 7 - 9 Emulsify & hydrolze fat in presence of bile salts Range 50 - 175
32
What does the Lundh Test do
- Measures the ability of the pancreas to respond to the hormone secretin - The small intestines produce secretin in the presence of partially digested food - Secretin stimulates the pancreas to secrete a fluid with a high concentration of bicarbonate - Contents of the duodenal secretions are aspirated (removed with suction) and analyzed over a period of about two hours
33
When use Computed tomography (CT) scan with contrast dye
- Pancreatic necrosis - Abscess - Pseudo cyst
34
What is hallmark of pancreatitis?
Chain of lakes (calcium i think)
35
Why use abdominal US?
- Detect gallstones - Ascites - Enlarged common bile duct / abscess / pseudocyst.
36
Why use Endoscopic retrograde cholangiopancreatography (ERCP)?
Structure of the common bile duct, other bile ducts, and the pancreatic duct
37
Why use endoscopic ultrasound?
Diagnosing severe pancreatitis - when an invasive test such as ERCP might make the condition worse
38
Why use Magnetic resonance cholangiopancreatography
to look at the bile ducts and the pancreatic duct.
39
When is lipase & amylase bad?
has to be 3x normal limit
40
What must you exclude if amylase is increased?
- Gut perforation - Ischemia - Infarction
41
How do you diagnose CF?
Sweat chloride >60 mmol/L n two separate occasions
42
Other lab findings for pancreatic disease?
Hypocalcemia Hyperglycemia Hyperbilirubinemia Hypertriglyceridemia
43
Stool fat content?
Children upto 6 yrs. of age
44
Blood Test for tumor markers in pancreatic cancer?
Carcinoembryonic antigen (CEA) and CA 19-9 are elevated in people with pancreatic cancer.