GI 2 Flashcards

1
Q

What is the Schilling Test for B12?

A
  • To detect pernicious anemia (autoimmune destruction of intrinsic factor)
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2
Q

What results can you get from Schilling Test?

A
  • Pernicious anemia
  • Intestinal malabsorption
  • Hypothyroidism
  • Liver disease
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3
Q

What is Meckel’s Diverticulum?

A

a true diverticulum of the ileum containing all 3 layers of the bowel wall.

(mucosa, submucosa, musclaris propria)

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4
Q

What is present in 50% of patients with Meckel’s Diverticulum?

A

Heteroropic tissue (gastric mucosa & pancreatic tissue)

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5
Q

In all imaging modalities, findings of Meckel diverticulum are ______

A

Nonspecific

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6
Q

Meckel diverticula are diagnosed when?

A

during surgery or autopsy, with imaging playing a secondary role

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7
Q

What is more sensitive for Meckel’s Diverticulum?

A

Scintigraphy

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8
Q

When can you see jaundice in sclera?

A

When it is about 2 mg/dL

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9
Q

What ratio of AST / ALT suggests alcoholic or non-alcoholic?

A
  • more than 2 suggests alcoholic liver disease

- less than 1.0 suggests non-alcoholic liver disease.

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10
Q

What do elevated AST & ALT liver enzymes mean?

A

leakage from damaged cells

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11
Q

Levels >1000 IU/L suggest what?

A
  • Drug-induced hepatitis
  • Acute viral hepatitis (A or B)
  • Ischemic or autoimmune hepatitis.
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12
Q

What is GGT?

A

Raised GGT in patients with chronic liver disease is associated with bile duct damage and fibrosis

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13
Q

What is alkaline phosphate?

A

ALP comes mainly from the cells lining bile ducts but is also in bone

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14
Q

If the GGT concentration is normal, a high ALP result suggests what?

A

bone disease

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15
Q

What is SAAG?

A

Serum ascites albumin gradient. Use it to diagnose assets due to portal HTN

SAAG = serum albumin = ascitic fluid albumin

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16
Q

SAAG ratio interpretations?

A
  • more than 1.1 = portal HTN

- Less than 1.1 = peritoneal carcinomatosis, peritoneal TB, pancreatitis, nephrotic syndrome

17
Q

FOBT can detect how little blood loss?

A

5 mL blood / day

use 50 - 75 years old

18
Q

What drugs may cause GI bleeding?

A

iron, NSAIDs, aspirin, steroids

19
Q

What can cause FOBT false positive?

A
  • red meats within 3 days of test

- Colchicine, iron, etc

20
Q

What can cause FOBT false negative?

A

Vitamin C, interferes with the chemical reaction and prevents the color formation

21
Q

How long does baby poop moms blood?

A

3 - 5 days

22
Q

Fetal Hb is resistant to what?

A

alkali denaturation (adult is not)