GI Diseases Flashcards
What nutrients are absorbed in the Jejunum?
Major Macronutrients (Glucose, FA, Cholesterol, AA & Peptides)
Water Soluble Vitamins
Minerals
Electrolytes and Water
What Nutrients are absorbed in the Ileum?
Bile Acids
Fat and Cholesterol
Fat Soluble Vitamins
Vitamin B12
Electrolytes
Water
What happens to undigested carbohydrates in the colon?
They are converted to SCFA by colonic bacteria
What are symptoms of GERD?
Chronic heartburn
Chest pain
Nocturnal coughing spasm
Regurgitation
What are complications of GERD?
Inflammation of esophagus
Scar Tissue
Stricture: narrowing of esophagus
Esophageal Cancer
What are the associated factors with GERD?
Increased abdominal pressure (The lower esophageal sphincter is partially controlled by a pressure gradient)
Relaxed LES
Delayed gastric emptying
Sensitive esophageal mucosa
Pyloric obstruction
What are the pre-disposing conditions for GERD?
Obesity
Ascites - excessive fluid in the abdominal cavity associated with liver disease
Scleroderma - a disease that leads to the hardening of tissues
Pregnancy - causes increased abdominal pressure
Delayed gastric emptying
Hiatus Hernia - part of stomach passes above diaphragm
Incompetent LES - this is congenital
What are the Treatments for GERD?
Lifestyle modification
Drug Therapy
Surgery
Antacids
What lifestyle modifications can you make for GERD?
Sit in an upright position for 1 hour after eating
Avoid eating 2-3 hours prior to going to bed
Avoid tight clothing in abdominal area
Stop smoking
Achieve and maintain a healthy weight
Eat smaller meals with less fat and more fibre
Elevate head of bed 15-20cm when sleeping
What foods may need to be decreased or eliminated from the diet to treat GERD?
Less fatty foods - fat delays gastric emptying and this may also help with weight loss
Chocolate, Caffeine - not causative but may help with decreased LES pressure
Nicotine and alcohol - causitive
Spicy and acidic foods - NOT CAUSITIVE but my irritate esophageal mucosa
What therapies besides nutrition therapy is used to treat GERD?
Drug Therapy:
Anti Secretory drugs that help to decrease gastric acid production. Examples include proton pump inhibitors, histamine H2 receptor antagonists
Motility agents that speed up gastric emptying
Surgery: tightening of LES
Antacids: to alleviate symptoms but will not change the disease process
What are some potential causes of dysphagia?
Anatomical - structural abnormalities such as a cleft palate or surgery used to treat head and neck cancers
Physiological - radiation used to treat cancers
Neurological - stroke, cerebral palsy, muscular dystrophy
Drug induced - sedation, ataxia, some anti depressants
What are the major warning signs of oral dysphagia?
Drooling, expectoration during/after swallowing
Slow rate of intake/chewing
Altered posturing of head/neck
food residue in mouth after eating
Coughing before swallowing
Alterations in voice quality - sound of a wet voice or aphonia (inability to vocalize)
Abnormal/absent laryngeal elevation
Unexplained weight loss
Briefly outline the phases of the swallow:
Oral Phase - the bolus of the food travels to the back of the throat, the UES is still closed. Tongue is elevated from anterior to posterior to trigger the swallow. This phase is affected by surgical defects that may cause tongue weakness, neurological disability and cognitive statues/level of awareness.
Swallow/Pharyngeal phase - soft palate elevates (known as velar elevation) to close off nasopharynx and prevent nasopharyngeal regurgitation. Constrictor muscles contract (known as pharyngeal peristalsis) and the tongue base drives the bolus posteriorly.
Esophageal Phase - upper esophageal sphincter opens and then closes once bolus enters the esophagus where it is propelled through the esophagus through peristaltic contractions. The lower esophageal sphincter relaxes and the bolus moves into the stomach
What are the three types of thickened fluids?
Nectar - mildly thick
Honey - moderately thick
Pudding - extremely thick
What are the main AHS texture modified Diets?
Pureed, Minced, Dysphagia Soft
Bonus - easy to chew