GI / Colorectal

Question 1

KRAS Wild Type LEFT sided colon cancers - targeted therapy

Answer 1

Cetuximab

Question 2

KRAS Wild Type RIGHT sided colon cancers
- targeted therapy

Answer 2

Bevacizumab

Question 3

Lynch syndrome - mutation

Answer 3

MLH1, MSH2, MSH6, PMS2

Question 4

Lynch syndrome increases risk of other malignancies

Answer 4

Endometrial&raquo_space;
Stomach
GU
Small intestine

Question 5

Lynch syndrome -> colorectal ca

Answer 5

develops from adenomas
more commonly R sided

Question 6

Peutz-Jeghers Syndrome Mutation

Answer 6

Autosomal dominant
STK11