GI Carcinomas Flashcards
What percentage of cancer diagnoses are gastric?
2%
What is the epidemiology of gastric cancers (age, sex)
> 75 years, male predominance 2:1
Risk factors of gastric cancer (5)
H.Pylori
Atrophic gastritis
Diet (salt, nitrates)
Smoking
Blood group
Red flag symptom of gastric cancer
Early satiety
Features of gastric cancer
Abdo pain, weight loss and anorexia, nausea and vomiting, dysphagia (proximal stomach), overt upper GI bleed, left supraclavicular node, periumbilical nodule
Periumbilical nodule is known as what?
Sister Mary Joseph’s node
Left supraclavicular node is known as what and associated to what?
Virchows node - gastric cancer
What are signet ring cells
Cells with a large vacuole, nucleus pushed to the top of the cell
Found in glandular cells that line digestive organs associated to gastric cancer
What is used to diagnose gastric cancer
OGD with biopsy
How is staging done in gastric cancer
CT
How do signet cells associated with prognosis
Higher number of signet cells = worse prognosis
How to manage gastric cancer (3 surg, 1 med)
Surgical options - endoscopic mucosal resection, partial gastrectomy, total gastrectomy
Chemo
What is intussusception
Part of the bowel sliding into an adjacent part of the bowel
Where does intussusception occur mostly
Ileo-caecal region
What age does intussusception occur mostly and sex
6-18 months, boys 2:1