GI Block Flashcards
Glucose and galactose enter the epithelial cells by…
The SGLT 1 transporter
By secondary active transport
Na+ contratransport
Fructose enters the cell by
Facilitated diffusion by the GLUT-5 transporter.
It cannot be absorbed against electrochemical gradient
How does glucose, galactose and fructose exit the cell?
GLUT-2 transporter via facilitated diffusion
Monosaccharides
Glucose, galactose, fructose
How does monosaccharides enter the cell?
Simple diffusion
Amylase
Hydrolyzes polysaccharides to disaccharides
Found in the mouth, stomach, small intestines
Disaccharidase
Found n the brush border of the small intestine epithelial cells. Hydrolyzes disaccharides into monosaccharides.
Maltase
Hydrolyzes maltose to 2 molecules of glucose.
Lactase
Hydrolyzes lactose to glucose and galactose
Sucrase
Hydrolyzes sucrose to fructose and glucose.
Lactose intolerance
When a lactase deficiency causes failure to digest a carbohydrate, lactose to an absorbable form, glucose and galactose.
Lactose remains in the cell and holds water in the lumen causing diarrhea and cramping.
Gas due to fermentation of lactose methane and hydrogen gas.
What begins digestion of protein in the stomach.
Pepsin a gastric protease from chief cell. It is no essential.
Pancreatic protease
Continues protein digestion in the small intestines. They are considered essential enzymes.
Examples are trypsin, chymotrypsin elastase and carboxypeptidase A and B