GI Flashcards
Dysphagia
solid only tends to be
solids and liquids tends to be
oropharyngeal dysphagia tends to be
Solid: mechanical
solid and liquid: motility disorder
oropharyngeal: neuromuscular disorder
Dysphagia, underlined cause
infectious
immunologic
motor/nerve dysfunction (2)
infectious: botulism
immunologic: myasthenia gravis
motor/nerve dysfunction (2): achalasia and cranial nerve palsy’s
Esophageal rupture
most common cause
Mallory Weiss tear
most common location
Most esophageal ruptures are iatrogenic
Mallory Weiss: GE junction
Boerhaave’s syndrome
age, sex
physical finding with eponym
chest x-ray findings(4)
age, sex: male, 40 to 60
physical finding with eponym: mediastinal air with Hamman’s crunch
chest x-ray findings: mediastinal air, left pleural effusion, pneumothorax, widened mediastinum
Pneumomediastinum with subcutaneous emphysema
Esophageal foreign body
levels of narrowing (4)
coin x-rays, AP versus transverse orientation
–Cricopharyngeus muscle (C6)
–Aortic arch (T4)
–Tracheal bifurcation (T6)
Gastroesophageal junction (T11)
Coin xrays: AP-coin in trachea, transverse-coin in esophagus (eg round aspect facing you on AP xray)
Esophageal foreign body
Swallowed battery, management when located in
esophagus (2)
stomach
pylorus
esophagus: immediate removal. Antibiotics
stomach and pylorus: only removed when not passing spontaneously within 72 hours
Esophageal food impaction
medical management (3)
avoid
medical management (3): glucagon, nifedipine, carbonated beverage
avoid: meet tenderizer-papain
Caustic ingestions
best diagnostic method
indication for dilution
indication for neutralization
best diagnostic method: endoscopy
indication for dilution: only solid alkali ingestion
indication for neutralization: only hydrofluoric acid (milk of Mag Citrate)
Peptic ulcer disease
rare risk factor
less known medical treatment option
Zollinger Ellison syndrome
surface protectant: sucralfate
UGIB
predictors of need for severe intervention (3)
Red blood on lavage
tachycardia
hemoglobin < 8
UGIB
most common cause
because more common in pregnancy
most common cause: PUD, usually duodenal
because more common in pregnancy: esophagitis
UGIB
therapy for variceal hemorrhage (3) (non-endoscopy)
Linton tube?
Octreotide, vasopressin, Blakemore tube
Linton tube - for gastric varices
Bilirubin
increased unconjugated (2) increased conjugated (3)
increased unconjugated: hemolysis or Gilbert’s syndrome
increased conjugated: hepatocellular disease, obstruction, CHF
Hepatitis A
mitigation options (2)
Prophylaxis with vaccine, immunoglobulin within two weeks of exposure
Hepatitis B marker significance
HBsAg
HBsAb
HBeAg
HBcAb
HBsAg: positive early, active infection
HBsAb: positive after clearance of HBsAg, best marker for immunity to HBV
HBeAg: implies high infectivity
HBcAb: best indicator of history of hepatitis B infection
Hepatitis B, postexposure prophylaxis for
previously unvaccinated
vaccinated, incomplete
vaccinated
previously unvaccinated: hepatitis B immunoglobulin, vaccination
vaccinated, incomplete: booster
vaccinated: test for HBsAb - if adequate titers, no treatment, otherwise HBIG and booster
Hepatitis C
cirrhosis/cancer risk
seroconversion risk after needlestick
cirrhosis/cancer risk: 50% versus 10% for hepatitis B
seroconversion risk after needlestick: 2%
Hepatitis-other types, description/transmission mechanism
Delta
E
G
Delta: blood-borne,IVDU, homosexual higher risk
E: fecal oral, found in Asia, Africa, Russia
G: blood-borne and STD
Hepatitis - indications for hospitalization (7)
Encephalopathy,
PT/INR significantly increased,
dehydration,
hypoglycemia,
bilirubin over 20,
age over 45,
immunosuppression
Hepatic encephalopathy treatment
avoid
precipitants
neomycin, lactulose, decrease dietary protein,
avoid sedatives, avoid bicarbonate
precipitants: LIVER = Librium [sedatives], Infection, Volume loss, Electrolytes disorders, Red blood cells in the gut
AND dietary protein access, worsening liver function