GI Flashcards
Accessory Digestive Organs
- Parotid salivary gland
- teeth
- tongue
- sublingual salivary gland
- submandibular salivary gland
- liver
- gallbladder
- pancreas
GI tract digestive organs
- oral cavity
- pharynx
- esophagus
- stomach
- large intesine
- small intestine
- anus
GI tract structural features
- mucosa (thick in esophagus; important in tumors; sometimes not called carcinoma until it is beyond this layer)
- epithelial lining
- lamina propria (loose connective tissue)
- muscularis mucosa
- submucosa (dense connective tissue)
- muscularis propria (largest layer)
- serosa (loose connective tissue)
Esophagus
mucosa–>submucosa–>muscularis–>adventitia
*no serosa, this is important in tumors becaues invasion is worrisome; squamous epithelia are normal in esophagus
Stomach
Mucosa (simple columnar epithelium) –>submucosa—>muscularis (oblique, circular, longitudinal)–>serosa
*more columnar and different type of epithelium as opposed to squamous in esophagus, also has serosa now.
*if you see a big vessel, you are in submucosa—none in epithelium
Small intestine
- simple columnar cell (enterocyte)
mucosa–>submucosa–>muscularis (inner circular layer; outer longitudinal layer) –>serosa; starts with a circular fold–>villi–>microvilli
- has goblet cells (loss of microvilli= microvilli inclusion disease)
- lymphatic nodule, intestinal gland
Colon
simple columnar epithelium
mucosa–>submucosa–>muscularis mucosa (circular, longitudinal) –>serosa (except in rectum, weaker protection)
intestinal gland, lymphatic nodule
inflammatory cells ok
Digestive functions of liver
- production of bile,
- hepatocytes are the key cells (binucleated, respect borders, squamous, lots of nucleoli and cytoplasm),
- synthesis of plasma proteins
- conversion of amino acids into glucose
- production of urea
- storage of glucose
- storage of vitamin A
- storage of iron
Digestive functions of pancreas
- a mix of exocrine and endocrine gland
- produces digestive enzymes and hormones
- exocrine function (acinar), 1.5 L of alkaline pancreatic juice per day into the duodenum, proteases, amylase, lipases
- endocrine function (islets of Langerhans), insulin, glucagon, somatostatin
- 90% of tumors in pancreas from acinar structures
Esophagus
Stomach
Small intestine
Colon
Appendix
Rectum/Anus