GI Flashcards
Signs and Symptoms of Peptic Ulcer disease
Gnawing epigastric pain
Relief of pain with eating (duodenal ulcers)
Pain worsens with eating (gastric ulcers)
GI bleeding
Signs of bowel perforation
Severe pain
“board-like” abdomen, rigidity
quiet, ominous bowel sounds
Lab and diagnosis of peptic ulcer disease
Normal except maybe some anemia on CBC
Consider endoscopy after 8-12 weeks of treatment
Consider H. pylori testing
Outpatient management of peptic ulcer disease
H2 Blockers first, then BID H2 blockers, then PPI, then refer for scope.
Breakthrough- Pepto bismol (bismuth subsalicyclate), Antacids like Mylanta, Maalox)
People on chronic PPI therapy should also have what supplement?
Calcium with vitamin D
Medications for Prevention of Peptic Ulcer Disease
People who can’t get off NSAIDs need PPI ordered daily
Misoprostol (Cytotec)- prophylaxis against NSAID induced ulcers (may stimulate uterine contraction and cause abortion)
H. pylori eradication options
2 antibiotics + PPI or bismuth
1. MOC- metronidazole, omeprazole, clarithromycin
2. AOC- amoxicillin, omeprazole, clarithromycin
3. MOA- metronidazole, omeprazole, amoxicillin
Then- antiulcer therapy for 3-7 weeks with PPI
GERD causes
incompetent lower esophageal sphincter (LES)
delayed gastric emptying
Signs/symptoms of GERD
retrosternal "burning" bitter taste in mouth belching, hiccups, dysphagia worse at night/laying down may be relieved with sitting up, antacids, water
Anyone with long-term GERD problems should…
Be referred for EGD to rule out Barrett’s esophagus or cancer
(by 5 years)
Treating GERD
- Lifestyle changes
- Antacids PRN
- H2 blockers, then H2 blockers BID
- Then PPI
- Then consider GI referral
What can be used for traveler’s diarrhea prophylaxis?
Pepto bismol (bismuth subsalicyclate)
When is further testing warranted for gastroenteritis in adults?
Symptoms lasting greater than 72 hours, or blood noted in stool
Check stool culture, WBC, and for ova and parasites
Causes of hepatitis
Viral- A, B, C (and more)
Autoimmune
Alcoholic
Common routes of hepatitis B transmission
Blood and blood products
Sexual activity
Mom to baby
Common routes of hepatitis C transmission
Often unknown
Traditionally associated with blood transfusion
About half of all cases related to IV drug use
Signs/symptoms of hepatitis
Pre-icteric: flu-like symptoms, aversion to smoke and alcohol
Icteric: weight loss, jaundice, pruritis, RUQ pain, clay colored stool, dark urine, low grade fever, hepatosplenomegaly