GI

Question 1

Complications of GERD

Answer 1

• Erosive esophagitis
• Peptic stricture (dysphagia)
• Esophageal ulcer
• Barrett’s esophagitis: columnar epithelium dysplasia
• Recurrent pneumonia – lipid-laden MPhages on bronchoscopy
• dental pitting
• Laryngitis, pharyngitis

Question 2

Tx GERD

Answer 2

• Behavior (diet, smoking, sleep position) + antacids
• II: H2 blocker
• III: PPI
• IV: promotility agent (e.g. metoclopramide)
• V: combination Tx
• VI: surgery (fundoplication