GI Flashcards
1
Q
What is the congenital aganglionosis ?
A
Congenital aganglionosis, or overo lethal white syndrome, is a syndrome that affects white American Paint Horse foals born from overo-overo matings (homozygous for mutated endothelin receptor B gene EDNRB).
Affected foals suffered from aganglionosis of the distal small intestine and large intestine, which results in a lack of intestinal motility leading to colic.
Fatal condition
