GI Flashcards

1
Q

List 3 signs which may be elicited on abdominal examination of this patient.

A

Tinkling bowel sounds
Hyperresonant bowel
Abdominal distension

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2
Q

UC signs may seen in a patient

A

Uveitis/episcleritis, arthritis/arthralgia, pyoderma gangrenosum/erythema
nodosum, mouth ulcers

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3
Q

1st line for UC

A

5 – Amino-Salicylates (e.g. sulfasalazine, mesalazine)

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4
Q

Diagnostic for Pancreatic cancer

A

Protocol CT pancreas

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5
Q

Stroking the inside of his thigh results in no elevation of the affected testis.
Elevation of both his testes relieves none of his pain too. What are these 2 signs known as?

A

Negative cremasteric reflex (1) and negative Phren’s sign

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6
Q

Suggest 4 complications of CKD.

A

Anaemia, Osteodystrophy (e.g., osteoporosis), CVD, Encephalopathy/Neuropathy

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7
Q

Liver role

A
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8
Q

H.Pylori pathogenesis

A

Helicobacter pylori has 2 main mechanisms to survive in the acidic gastric environment:
- chemotaxis away from low pH areas, using its flagella to burrow into the mucous lining to reach the epithelial cells underneath
- secretes urease → urea converted to NH3 → alkalinization of acidic environment → increased bacterial survival

Pathogenesis mechanism:
Helicobacter pylori releases bacterial cytotoxins (e.g. CagA toxin) → disruption of gastric mucosa

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9
Q

What do you classify stool

A

Bristol Stool Chart

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10
Q

If terlipressen is contraindicated for Oesphageal varices what should be used instead ?

A

IV somatostatin

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11
Q

what cytoplasmic inclusion would you see in hepatocytes in patients with alcoholic hepatitis?

A

Mallory bodies

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12
Q

What two pathological factors contribute to the formation of ascites?

A

High portal venous pressure
Low serum albumin

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13
Q

Name 3 complications of diverticulosis?

A

Haemorrhage
Peritonitis
Perforation
Fistulae
Abscess
Post-infective strictures

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14
Q

Which of the following is not an
obstructive cause of dysphagia?
A. Pharyngeal carcinoma
B. Oesophageal web
C. Retrosternal goitre
D. Peptic stricture
E. Achalasia

A

Achalasia

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15
Q

Duodenal Ulcers symptoms improve before/after meals

A

after meals

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16
Q

Best diagnoses for hiatus hernia

A

Barium meal

17
Q

What are the most common cause of upper GI bleed

A

Peptic ucers

18
Q

Which of the following
medications would act as prophylaxis in preventing a rebleed from his oesophageal
varices?

A

Propanolol

19
Q

Lower/Raised MCV for alcoholic related liver disease

A

Raised MCV

20
Q

CKD treatment

A

Prednisolone

21
Q

Where is Vitamin B12 absorbed

A

Terminal ileum

22
Q

Test for cirrhosis regarding alpha 1 antitrypsin

A

Liver Biopsy which shows cirrhosis and positve Acid Schiff globules

23
Q

Test for lung disease regarding alpha 1 anitrypsin

A

High resoltion CT thorax

24
Q

Management for Wilsons disease

A

Pencillamine
Trientene
Copper Chelation

25
Anti spasmodics medication
Hyoscine butylbromide (Buscopan) Mebeverine
26
Specialsit laxatives used for IBS
Linaclotide
27
Viral causes of gastententeritis
Norovirus Rotavirus
28
G.S for Crohn's
Endoscopy +/- biopsy
29
Crohn's management
INDUCING REMISSION First line: Steroids (e.g. oral prednisolone or IV hydrocortisone) 2nd:Azathioprine Mercaptopurine Methotrexate Infliximab Adalimumab MAINTAINING 1st Line: Azathioprine Mercaptopurine
30
UC management
31
Test used to confirm CLL
Immunophenotyping
32
CLL treatment
Radio Chemo Stem Cell At risk of neutropenic sepsis/sepsis
33
C.difficile what is it?
anaerobic gram-positive, spore-forming, toxin-producing bacillus
34
What does Hpylori stain with
Silver Stain
35
Diabetes type one gene + hypersenstivity reaction
4 HLA DR3 + 4