GI Flashcards
Alpha cell
Secrete Glucagon
Beta cell
Secrete insulin
Delta cell
Inhibit alpha and beta cells from releasing glucagon and insulin
Pancreas secretes
Bicarbonate for stomach acid
Water
Na and K
Digest enzymes trypsin, amylase, lipase
Acute panc s/s
Boring abd pain, all quads and lumbar Rigid abd no rebound tenderness BL crackles, L pleura effus L lobe collapse Raised diaphragm Amylase⬆️ Lipase⬆️ Calcium⬇️ Bg ⬆️ Surfactant⬇️from💀alveolar cells
Cullen sign
Blue discolor and bruising of umbilicus from methylalbumin formation from acute panc, intraperitoneal bleed
Grey Turner sign
Bruised flank, can be retro bleed, from acute panc
Acute panc tx
Fluids Ca++,K+,Mg++ H2 blocker or PPI NG suct TF below duodenum Monitor for ARDS, diaphragm elevation, atelectasis, and l sd plearual effus
Upper GIB tx
Address cause Fluids PRBC Clotting factor replacement Vasopressin-constrict spleen art bed, ⬇️portal vein HTN Octeotride -⬇️spleen blood flow GI motil Lactulose-excrete nitrous content pvn ammonia Bblocker -⬇️portal vein flow
Hepatic failure labs
Protein⬇️ Albumin⬇️ Ascites Ammonia⬆️ Pancytopenia Coagulopathy AST/ALT⬆️ Bilirubin⬆️ BG⬇️ RR⬆️ Creatinine⬆️
Hepatic failure s/s
AMS Asterixis (flapping hand tremor) Ascites Jaundice Renal fail Sepsis Liver starts inflamed then shrinks
Factors increasing serum ammonia
K⬇️
BUN⬆️
LA⬆️
Protein⬆️
Manage Hepatic failure
K sparing diuretic(Aldactone) Neomycin to kill NH3 gut bacteria Lactulose for NH3 Prevent ⬆️BUN, GIB, acid buildup Tips procedure
Spleen
Hx of splenectomy has poor immune fn, kehr sign, abdominal distention no bowel sounds, LUQ
Kehr Sign
Sharp L shoulder pain associated with ruptured spleen