GI Flashcards
Linaclotide (linzess)
- IBS-C (if peg not working)
- Activates guanylate Cyclase —> stimulates cGMP —> increase intestinal fluid/motility
- Similar drug: plecanatide (trulance)
LA grade b esophagitis
Atleast 1 mucosal break > 5mm long but not continuous between the tips of adjacent mucosal folds
LA grade c esophagitis
Atleast 1 mucosal break that is continuous between the tips of the adjacent mucosal folds but no circumferential
La grade d
Mucosal break that involves Atleast 3/4 luminal circumference
La grade A esophagitis
One or more mucosal breaks each < 5mm in length
Eluxadoline (viberzi)
- Abdominal pain and IBS-D
2. Binds to opiate receptors and inhibits peristalsis
Lubriprostone (amitiza)
- IBS-C
2. Activate CIC-2 chloride channels which increases intestinal fluid secretion/motility
4 medications to treat abdominal pain in IBS
- Hysocyamine (levsin): anti-spasmodic
- Dicyclomine (Bentyl): AS + AC
- SSRI (C)
- TCA (D)
IBS-D (4 medications)
- Loperamide
- Eluxadoline
- Rifaximin
- TCA (abdominal pain)
Rifaximin
- Global symptoms for IBS-D
2. Inhibits bacterial RNA synthesis by binding to bacterial DNA-Dep RNAP
IBS-C (3 medications)
- Lubriprostone (amitiza)
- Linaclotide (linzess)
- SSRI (abdominal pain)
Forrest 2A
Non-bleeding visible vessel
-endoscopic therapy and high dose PPI
Forrest 2B
Adherent clot
- no recc for/against endoscopic therapy
- high dose PPI
Forrest 2C
Flat pigmented spot
-standard PPI
Forrest 3
Clean based ulcer
Forrest 1A
Active spurting bleeding
Forrest class 1B
Active oozing bleeding
Type 1 biliary cyst (4 subtypes)**
Cystic or fusiform dilation if CBD
A. Cystic dilation of CBD, part/all of the CHD and EH portions of the left/right hepatic ducts *
B. Focal segmental dilation of an EH bile duct (typically CBD)
C. Smooth fusiform, dilation of all the EH bile ducts *
D. Cystic dilation of common and cystic duct
Type 2 biliary cysts
True diverticula of the EH bile ducts
Type 3 biliary cysts (2 types)
Choledochoceles (Intraduodenal portion of the distal CBD)
A. Bile duct and pancreatic duct enter cyst, which then drains into duodenum at separate orifice
B. Diverticulum of the intraduodenal CBD or intra-ampullary common ductal channel
Type 4 biliary cysts (2 types)**
Multiple cysts
A. Both IH and EH cystic dilations
B. Multiple EH cysts
Type 5 biliary cyst
One or more cystic dilations of the IH ducts
-presence of multiple saccular or cystic dilations is known as caroli disease
Type 6 biliary cyst
Isolated cystic dilations of the cystic duct
