GESTATIONAL TROPHOBLASTIC DISEASE/MOLAR PREGNANCY (HYDATIDIFORM MOLE)

Question 1

GESTATIONAL TROPHOBLASTIC
DISEASE or

Answer 1

MOLAR PREGNANCY
(HYDATIDIFORM MOLE)

Question 2

It is the abnormal
proliferation &
degeneration of the
trophoblastic chorionic
villi. As the cells
degenerate, they become
filled with fluid & appear
as clear, fluid-filled,
grape-sized vesicles & the
embryo fails to develop

Answer 2

GESTATIONAL TROPHOBLASTIC
DISEASE

Question 3

RISK FACTORS

Answer 3

⚫ Increased or decreased maternal age
⚫ Low socioeconomic status; low protein diet
⚫ History of abortion and Clomiphene therapy

Question 4

2 Types of H Mole

Answer 4

1. Complete Mole
2. Partial Mole

Question 5

All trophoblastic villi swell & become cystic; embryo
dies early

Answer 5

Complete Mole

Question 6

complete mole
Chromosomes are

Answer 6

are normal, 44xy or 44xx

Question 7

complete mole may lead to

Answer 7

choriocarcinoma

Question 8

Some of the villi form normally

Answer 8

Partial Mole

Question 9

what layer in partial mole is swollen & misshapen

Answer 9

Syncytiotrophoblast layer

Question 10

partial mole has ____ chromosomes

Answer 10

69 (3 chromosome instead of 2 for every pair)

Question 11

some assessment

Answer 11

⚫ No fetal heart sounds
⚫ Positive pregnancy test
⚫ Abdominal pain

Question 12

Expulsion of molar cyst by

Answer 12

16th-18th week

Question 13

Vaginal bleeding in the 1st trimester, may be brown
like

Answer 13

prune juice & may contain grapelike
vesicles

Question 14

diagnosis
first sign is

Answer 14

Passage of vesicles

Question 15

⚫ TRIAD SIGNS;

Answer 15

⚫ Big uterus
⚫ Vaginal bleeding: brownish, intermittent
⚫ HCG > 1 M(NV: 400,000 IU/24hrs)

Question 16

to detect early lung metastasis

Answer 16

Chest X-ray

Question 17

Chest X-ray to detect

Answer 17

early lung metastasis