Germinal stage Flashcards

1
Q

What period is the germinal stage?

A

time from fertilisation to end of 2nd week.

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2
Q

What is the gestational age?

A

time from last menstruation (embryonic age + 2 weeks)

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3
Q

What is the embryonic age?

A

time since fertilisation

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4
Q

What is the foetal period?

A

9th- 38th week

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5
Q

What is the embryonic period?

A

3rd week - end of 8th week

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6
Q

Where does fertilisation take place?

A

ampullae region of the fallopian tubes

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7
Q

How much before ovulation must sperm be introduced to fallopian tube?

A

at most 5 days

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8
Q

What is capacitation of the sperm and why does it occur?

A

A change in sperms plasma membrane enabling it to fertilise the egg and a induction to swim faster.
occurs due to projesterone when they come close to the egg

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9
Q

How long is a secondary oocytes viable for in the fallopian tubes and uterus?

A

12-24 hrs

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10
Q

Why are sperm not rejected from father? (theyre forgein)

A

there are tight junctions in testicles so sperm never touch blood

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11
Q

What does semen contain to decrease risk of rejection of embryoblast and what does it do to female behavoir?

A

immuno surpressants and makes them more aggressive but happier

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12
Q

Describe what happens during fertilisation?

A
  • Sperm starts to burrow through corona radiata- an outer lining of granulosa cells
  • sperm then secrete digestive enzymes to break down zona pellucida
  • when break through zona pellucida it reaches plasma membrane and binds with receptor
  • receptor activates 2nd meiotic division of the ovum, and a male pronucleus to be formed ready for first mitotic division
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13
Q

Outline the changes to the ovum post fertilisation until implantation

A
  • as it starts dividing in the early cleavage phases (1-3 days) it is a mass of cells within the zona pellucida called a ZYGOTE
  • Then becomes morula for 3-4 days post fetilisation
  • Then becomes blastocytst as the trophoblast starts to develop (4-5 days)
  • The zona pellucida is still present at this stage and this prevents implanation, so the blastocyts goes through contractions and expansions in order to hatch out of the zona pellucida.
  • The blastocyst now composes of an outer layer of trophoblast, an embryoblast layer at the top, a primitive endoderm just below this and a blastocysts cavity filling the rest of the space
  • Implantation occurs at the 6th day
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14
Q

What is the role of the trophoblast?

A

provides nutrients before it implants. Will later become the yolk sac and placenta

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15
Q

Where is the normal implantation site?

A

upper, posterior part of the uterus in the endometrium

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16
Q

Where does the embryo implant for ectopic pregnancies?

A

fallopian tubes

17
Q

What is the first stage to implantation?

A

The trophoblast differentiates into syncytiotrophoblast, which surrounds the blastocyst as it enters into the endometrium. The rest of trophoblast remains as a outer layer of cells but is now called the cytotrophoblast.

18
Q

What does the embryoblast layer differentiate into on day 8?

A

the hypoblast and the epiblast, which form the bilaminar embryonic disc

19
Q

What cavities does the hypoblast go on to create by day 13?

A

the chorionic cavity (largest, goes around everything) and yolk sac (on inside of hypoblast)

20
Q

What cavity does the epiblast create?

A

the amniotic cavity