Germinal stage Flashcards
What period is the germinal stage?
time from fertilisation to end of 2nd week.
What is the gestational age?
time from last menstruation (embryonic age + 2 weeks)
What is the embryonic age?
time since fertilisation
What is the foetal period?
9th- 38th week
What is the embryonic period?
3rd week - end of 8th week
Where does fertilisation take place?
ampullae region of the fallopian tubes
How much before ovulation must sperm be introduced to fallopian tube?
at most 5 days
What is capacitation of the sperm and why does it occur?
A change in sperms plasma membrane enabling it to fertilise the egg and a induction to swim faster.
occurs due to projesterone when they come close to the egg
How long is a secondary oocytes viable for in the fallopian tubes and uterus?
12-24 hrs
Why are sperm not rejected from father? (theyre forgein)
there are tight junctions in testicles so sperm never touch blood
What does semen contain to decrease risk of rejection of embryoblast and what does it do to female behavoir?
immuno surpressants and makes them more aggressive but happier
Describe what happens during fertilisation?
- Sperm starts to burrow through corona radiata- an outer lining of granulosa cells
- sperm then secrete digestive enzymes to break down zona pellucida
- when break through zona pellucida it reaches plasma membrane and binds with receptor
- receptor activates 2nd meiotic division of the ovum, and a male pronucleus to be formed ready for first mitotic division
Outline the changes to the ovum post fertilisation until implantation
- as it starts dividing in the early cleavage phases (1-3 days) it is a mass of cells within the zona pellucida called a ZYGOTE
- Then becomes morula for 3-4 days post fetilisation
- Then becomes blastocytst as the trophoblast starts to develop (4-5 days)
- The zona pellucida is still present at this stage and this prevents implanation, so the blastocyts goes through contractions and expansions in order to hatch out of the zona pellucida.
- The blastocyst now composes of an outer layer of trophoblast, an embryoblast layer at the top, a primitive endoderm just below this and a blastocysts cavity filling the rest of the space
- Implantation occurs at the 6th day
What is the role of the trophoblast?
provides nutrients before it implants. Will later become the yolk sac and placenta
Where is the normal implantation site?
upper, posterior part of the uterus in the endometrium