Geris Flashcards
1
Q
Tau - dementias
A
AD (+ b amyloid plauqe) - neurofibrillary tangles
FTD
Atypical - PSP, CBD
2
Q
Alpha synaclein dementias
A
PD
LBD
MSA
(alphas PaLM)
3
Q
Type of brain finding in PD
A
Alpha syn
4
Q
Type of brain finding in MSA
A
Alpha syn
5
Q
Type of brain finding in LBD
A
Alpha syn
6
Q
Type of brain finding in AD
A
Tau
7
Q
Type of brain finding in CBD
A
Tau
8
Q
Type of brain finding in PSP
A
Tau
9
Q
Type of brain finding in FTD
A
Tau
10
Q
Frailty criteria includes
(Simplified Fried)
A
3 of:
- decreased grip strength;
- unintentional weight loss (>5% over 3 months, or 10% over 6 months);
- low energy;
- low physical activity
- slow walking speed (<0.8m/s)
11
Q
AD - Rx (& MoA)
A
Mild-mod: Cholinesterase inhibitors (Donepezil, Rivastigmine)
Severe: Memantine (Noncompetitive NMDA antagonist + Dopamine agonist)
?Melatonin
