Genetics

Question 1

Prader Willi syndrome

Answer 1

C/S 15 - Maternal imprinting
So mutations in fathers c/s 15
(or maternal UPD15)

PrA - paternally active

Question 2

Angelman

Answer 2

MAn - maternally active
Deletions of maternally active cs 15
or paternal UPD 15

Question 3

C/S 11 syndromes

Answer 3

Beckwith-Wiedemann syndrome
11p15.5 & patUPD11

Russell-Silver syndrome (dwarf)
11p15.5 and matUPD7 (then maternal imprinting)