Geriatrics Flashcards
define the pathophysiology of ageing
Major categories of impairment that appear with old age and affect the physical, mental and social domains of the elderly, usually due to many predisposing and precipitating factors, rather than a single cause
neurological physiological changes in ageing
Decreased wakefulness, brain mass, cerebral blood flow, increased white matter changes
neurological pathological changes in ageing
Increased insomnia, neurodegenerative disease, stroke, decreased reflex response
special senses physiological changes in ageing
Decreased lacrimal gland secretion, lens transparency, dark adaption, decreased sense of smell and taste
special senses pathological changes in ageing
Increased glaucoma, cataracts, macular degeneration, presbycusis, presbyopia, tinnitus, vertigo, oral dryness
CV physiological changes in ageing
Increased sBP, dBP, decreased HR, CO,
Decreased vessel elasticity, cardiac myocyte size and number, b-adrenergic responsiveness
CV pathological changes in ageing
Increased atherosclerosis, CAD, MI, CHF, hypertension, arrythmias, orthostatic hypotension
Resp physiological changes in ageing
Increased tracheal cartilage calcification, mucous gland hypertrophy
Decreased elastic recoil, mucociliary clearance, pulmonary function reserve
resp pathological changes in ageing
Increased COPD, pneumonia, PE
GI physiological changes in ageing
Decreased oesophageal peristalsis, gastric acid secretion, liver mass, hepatic blood flow, calcium and iron absorption
GI pathological changes in ageing
Increased cancer, diverticulitis, constipation, faecal incontinence, haemorrhoids, intestinal obstruction, malnutrition, weight loss
Renal physiological changes in ageing
Increased proteinuria, urinary frequency
Decreased renal mass, creatinine clearance, urine acidification, hydroxylation of vitamin D, bladder capacity
renal pathological changes in ageing
Increased urinary incontinence, nocturia, BPH, prostate cancer, pyelonephritis, nephrolithiasis, UTI
repro physiological changes in ageing
Decreased androgen, oestrogen, sperm count, vaginal secretion
Decreased ovary, uterus, vagina, breast size
repro pathological changes in ageing
Increased breast and endometrial cancer, cystocele, rectocele, atrophic vaginitis
endocrine physiological changes in ageing
Increased NE, PTH, insulin, vasopressin
Decreased thyroid and adrenal corticosteroid secretion
endocrine pathological changes in ageing
Increased NE, PTH, insulin, vasopressin
Decreased thyroid and adrenal corticosteroid secretion
MSK physiological changes in ageing
Increased calcium loss from bone
Decreased muscle mass, cartilage
MSK pathological changes in ageing
Increased arthritis, bursitis, osteoporosis, muscle weakness, gait abnormalities, polymyalgia rheumatica