Geriatric Flashcards

1
Q

Three acetylcholinesterase inhibitors used in mild to moderate Alzheimer’s

A

donepezil
galantamine
rivastigmine

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2
Q

MOA of memantine

A

NMDA receptor antagonist

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3
Q

NICE recommend memantine for:

A
  • moderate AD but cannot take AChE inhibitors
  • add-on to AChE inhibitors in patients with moderate or severe AD
  • monotherapy in severe AD
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4
Q

MMSE score - mild impairment

A

20 - 24

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5
Q

MMSE score - moderate impairment

A

13 - 20

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6
Q

MMSE score - severe impairement

A

<12

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7
Q

Lewy Body dementia, core clinical features

A

fluctuating cognition
visual hallucinations
parkinsonism

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8
Q

Pharmacological management of Lewy Body dementia

A

AChE inhibitors or memantine

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