Geri GI Flashcards
what is GERD?
Retrograde movement of stomach contents into esophagus secondary to transient relaxation of LES (incompetency)
causes of GERD?
- Sliding hiatal hernia (hernia of stomach thru diaphragm)
- Reduced LES pressure
- Reduced pinching action of Crus of Diaphragm
what are factors that aggravate GERD sx’s?
- Large meals
- Fatty foods
- Caffeine
- ETOH/smoking
- Obesity
- Supine after eating
what are the typical sx’s of GERD?
- Substernal burning with radiation to mouth/throat
- Sour tasting regurg
what are the atypical sx’s of GERD?
- Chronic cough
- Difficult-to-control asthma
- Laryngitis/hoarseness
- Recurrent chest pain
when is upper EGD done for dx of GERD?
in ALL pts w/new-onset GERD:
- > 50 y/o
- persistent/incomplete resolution of sx’s despite medical tx
- hx of acid reflux >5 years
how do you dx pts with atypical sx’s of GERD?
24hr pH probe after neg work-up
what other causes of atypical sx’s of GERD must be r/o?
Inferior MI, ACS, Aortic dissection, pulmonary disease
what are complications of GERD?
- Esophagitis
- Esophageal ulceration
- Bleeding
- Strictures
- Barrett esophagus
- Esophageal adenocarcinoma
pharmacologic tx of GERD?
PPIs and H2 receptor blocks (Famotidine, Ranitidine) - BEST AT NIGHT
Antacid liquids or tablets (temporary)
-Mylanta, Maalox, Tums, Rolaids
who is surgical tx for GERD reserved for? what is the surgery?
pts w/severe refractory GERD w/ complications
LAPAROSCOPIC FUNDOPLICATION - wrap upper part of stomach around LES to strength the sphincter, prevent acid reflux, and repair hiatal hernia
what is diverticulitis?
inflammation d/t micro perforation of a diverticulum
what is the MOST COMMON sx of diverticulitis?
LLQ Abdominal Pain (d/t involvement of sigmoid colon)
what is the pain like in diverticulitis?
CONSTANT (present for several days prior to presentation)
what is complicated diverticulitis?
Diverticulitis with:
- abscess
- obstruction
- fistula
- perforation (have peritoneal sx’s)
what may DRE and stool reveal for diverticulitis?
DRE may reveal mass in presence of a distal sigmoid abscess
Stool may be positive for occult blood
labs for diverticulitis
serum amylase and lipase normal or mildly elevated
UA reveals sterile pyuria d/t adjacent inflammation
what does presence of colonic flora on Ucx for diverticulitis suggest?
presence of a colovesical fistula
what is the imaging for diverticulitis?
CT scan w/PO contrast
what will you see on CT scan w/PO contrast for diverticulitis?
- Localized bowel wall thickening (>4mm)
- Increase in soft tissue density w/in pericolonic fat secondary to inflammation or fat stranding
- Presence of colonic diverticula
what are complications of diverticulitis?
abscesses
Bowel obstruction (dilated loops of bowel w/ air-fluid levels with pericolonic inflammation -> FAT STRANDING)
what is the tx of mild diverticulitis?
IV abx (for GN and anaerobic pathogens) until inflammation stabilized and pain/tenderness resolving (2-5 days)
Transition to PO abx (Cipro + Metro or Augmentin) for 10-14 days
Hospitalize if no improvmeent
tx for complicated diverticulitis?
surgery
what are the surgery indications for complicated diverticulitis?
- Failed med management
- Recurrent episodes of acute diverticulitis
- Peritonitis
- Failed percutaneous drainage of abscess
- Enterocutaneous fistula formation
- Bowel obstruction
what is the definition of constipation? seen in who?
Infrequent and/or unsatisfactory defecation < 3 times/week
> 65 y/o women
how long must sx’s of constipation be present for dx of CHRONIC constipation?
presence of sx’s for at least 12 weeks
is constipation a disease?
NO!!! IT’S A SYMPTOM
what are causes of constipation?
Changes in neuromuscular control of colon predispose to constipation (may occur with bed rest or constipating meds)
Passing hard stools or straining, incomplete or painful defecation
Hypothyroidism, Colon Cancer
disorders that are risk factors for constipation?
- Malignancy (colon ca)
- Endocrine/metabolic (DM, hypothyroidism, hypercalcemia, hypokalemia)
- Neuro d/o (Parkinson’s, diabetic autonomic neuropathy, spinal cord injury, dementia, stroke)
- Rheumatologic d/o (systemic sclerosis and other connective tissue d/o)
- Psych d/o (depression or eating d/o)
- Anatomic dysfxn (strictures, postsurgical abnormalities, anal fissures, megacolon, hemorrhoids
what are general risk factors for constipation?
- Female, >65 y/o
- Low caloric intake
- ***Polypharmacy
- Sedentary lifestyle
- Ignoring urge to defecate/chronic fecal retention
- Abnormal responses of the pelvic floor muscles during defecation
- Blunted rectal sensation