GERI-AGIN Flashcards
Why do we have a gray crisis?
- improved life expectancy
- decrease in birth rates
- public health improvements (abx, vaccination
What percentage of the population will be over 65yo by 2050?
30%! 82.5 million people
What are the two key theories behind the biology of aging?
Genetic Predisposition:
-things are predisposed to go badly for certain people
Wear and Tear: -accumulated pathology, carcinogens, cellular trauma, etc.
What is the rule of fourths things that impact aging over time?
1/4 disease,
disuse (atrophy),
misuse (injury)
physiology (elasticity, density - things don’t hold up over time)
What are some important characteristics of aging?
- increased mortality with age after maturation
- biochemical composition of tissues changes
- physiological capacity decreases
- decrease in response to environmental stimuli (more likely to hurt themselves because they’re not as sensitive to the outside world)
- increased vulnerability to disease
- epigenetic (telomeres, DNA changes over time, etc.)
What are some important age-related physical changes noted in the slides?
- blood pressure regulation: orthostasis
- volume regulation: dehydration, over-hydration
- thermoregulation: colder
- impaired immune response: increased infection
What are some important age-related sensory changes noted in the slides?
- vision: reduced lens elasticity
- hearing: increased vestibular sensitivity, reduced acoustic sensitivity
- taste: reduced
- smell: reduced
- touch: reduced reflex
How does the heart change with aging?
max HR is 195 in adults; reduces to 155 in geriatrics
How does the skin change with aging?
reduced elasticity - wrinkles!
How do the kidneys change with aging?**
reduced by 50% perfusion
How does the GI tract change with aging?
reduced peristalsis/secretions - elderly pts are often constipated
What happens to body composition during aging?
% body water = decreased
% body fat = increased
What happens to the brain during aging?
weight decreases by 7% atrophy
- more brain damage because there’s more space for the brain to move around and hit things during a fall
What happens to sleep patterns during aging?
markedly reduced stage 3 and 4 sleep more frequent awakenings, reduced sleep efficiency
What happens to bone mineral content during aging?
diminished by 10-30%
What happens to the prostate gland during aging?
increases by 100% - can be up to the size of a grapefruit!