GERD Flashcards
What is GERD
GASTROESOPHAGEAL REFLUX DISEASE
Characteristics of GERD (Pathophysiologic changes)
Ulcers
RISK FACTORS/ ETIOLOGY of GERD
1) LOW LES TONE
2) HIATAL HERNIA
3) HIGH HCL SECRETION
NSAIDS
Smoking
Alcohol
Zollinger Ellison Syndrome (gastroma releasing gastrin)
4) HIGH INTRAGASTRIC PRESSURE
Pregnancy
Obesity
Big meals
Gastroparesis
Clinical manifestations of GERD
Epigastric pain
Dyspepsia (Indigestion)
Heartburn
Dysphagia
Complications of GERD
Barrett’s esophagus
Adenocarcinoma
Strictures due to fibrosis
GI bleeding
Aspiration
Laryngitis
Odynophagia
DIAGNOSIS OF GERD
1) ECG
To rule out heart disease
2) EMPIRIC PPI TRIAL
3) COMPLICATIONS/ ALARM SYMPTOMS
Dysphagia
Vomiting
Anemia
Weight loss
4) MONOMETRY
Rule out Esophageal motility disorders
5) PH MONITORING
TREATMENT
PPI
HISTAMINE RECEPTORS AGONIST (H2RA)