Genome Projects Flashcards
What is the importance of gene sequencing projects?
Gene sequencing projects are important as they can lead to medical advances such as allowing us to identify which genes are more active/switched on in certain diseases. Furthermore, genome sequencing allows us to trace evolutionary relationships between species.
Describe the nature of the proteome.
-The proteome is the resulting network of proteins from the genome.
-There can be different types of proteome: cellular or organism.
How can the genome and proteome of simple organisms be determined?
(1) The majority of prokaryotes have just one section of DNA that is not associated with histones.
(2) There are no non-coding portions of DNA which are typical of eukaryotic cells
How can the genome and proteome of complex organisms be determined?
The problem in complex organisms is translating knowledge of the genome into the proteome. This is due to many non-coding genes being present. A human proteome project is underway.