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Pathology > Genitourinary Diseases > Flashcards

Genitourinary Diseases Flashcards

1
Q

Afferent arterioles

A

enter the glomerulus

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2
Q

Efferent arterioles

A

leave the glomerulus

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3
Q

Endothelial cells

A

line the arterioles

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4
Q

Pseudofenestrations

A

holes in the endothelials cells that line the arterioles

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5
Q

Glomerular basement membrane

A

located on top of the endothelial cells and below the visceral epithelial cells.

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6
Q

parietal epithelial cells

A

once the endothelial cells are in Bowman’s capsule

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7
Q

Juxtaglomerular Cells

A

control blood pressure

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8
Q

Mesangial cells

A

in the middle of arterioles
contract
heal the glomeruli
Monocytes are found here

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9
Q

Juxaglomeruli apparatus

A

Decrease BP in afferent arterioles

Decrease glomerular filtration rate

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10
Q

Glomerulonephritis

A

inflammation of the kidney parenchyma

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11
Q

Circulating immune Complex Glomerulonephritis

A

SPECIFIC, immune complexes form OUTSIDE the kidney in the subintimal space
TYPE III Hypersensitivity reaction

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12
Q

Antigenic Glomerulonephritis

A

formation of ANTIBODIES against ANTIGENS of the basement membrane
TYPE II Hypersensitivity reaction (Compliment dependent)
Formation of Immune complex WITHIN the kidneys

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13
Q

Heymann Glomerulonephritis

A

ANTIBODIES against visceral epithelial cells / Podocytes

Production of antibodies AGAINST hidden antigens

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14
Q

Permiability of Glomeruli

A

Water ONLY, not permeable to blood cells or protein

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15
Q

Nephritic Syndrome

A

hematuria
Oliguria / Azotemia
Uremia

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16
Q

Azotemia

A

a biochemical abnormality that refers to an elevation of BUN and creatinine

17
Q

Uremia

A

azotemia + clinical signs and symptoms

MORE SERIOUS

18
Q

Acute Proliferative Poststreptococcal Post Infectious Glomerulonephritis

A 
CHILDREN
Enlarged tonsils w/ white spots
Antibodies against antigens Streptococcal wall 
Beta Hemolytic Strep A group
Hematuria
Azotemia
Proteinuria
Hypertension
Molecular Mimicry
19
Q

Molecular Mimicry

A

confusion of antibodies that bind to normal active tissue instead of the pathogen
Type II or Type III Hypersensitivity Reaction

20
Q

Rapid Progressive Crescentic Glomerulonephritis

A

rapid & progressive loss of renal function

Pathology (2 decks)

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