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Pelvis and Gonads > Genitalia > Flashcards

Genitalia Flashcards

1
Q

Intermediate Mesoderm becomes..

A

Reproductive Organs

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2
Q

Endodermally derived yolk sac becomes..

A

sperm and eggs

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3
Q

Indifferent Gonads

A

5-7 weeks
germ cells from yolk sac
thickening of medial meonephros to from genital ridge

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4
Q

Migration of germ Cells along dorsal Mesentery

A

Week 4

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5
Q

Germ cells into primary sex cords

A

Week 6

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6
Q

Gonadal Ridge

A

From proliferating epithelium and mesenchyme

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7
Q

Gonad

A

external cortex, internal medulla

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8
Q

Sex Determination

A

Week 7

SRY gene in Y chromosome to produce TDF

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9
Q

Testes From Sex cords?

A

sex cords&raquo_space; Seminiferous cords&raquo_space; tubules&raquo_space; rete testes

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10
Q

Interstitial Cells of Leydig

A

adjacent to seminiferous tubules, produce testosterone

Week 8

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11
Q

Sertoli Cells

A

Part of Sem tubule, produce sperm, suppress mullein ducts (AMH)
MIS inhibits parames ducts

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12
Q

Mesonephric tubules in Males

A

Ree Testis

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13
Q

Mesonephric Duct in Males

A

Efferent Ductules, Ductus Epididymis, Ductus Deferens

Wolffian Ducts

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14
Q

Paramesonephric Ducts

A

Mullerian Ducts

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15
Q

Seminal Vesicle

A

along the ejaculatory duct, nourished the sperm

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16
Q

Prostate Derivation

A

Endodermal outgrowths surrounding mesenchyme

Transports sperm while giving it fluid for semen

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17
Q

Bulbourethral Glands

A

outgrowths of spongy urethra

contribute to semen

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18
Q

Paramesonephric ducts

A

develop lateral to gonads and mesonephric ducts

pass caudally, meet as Y uterovaginal primordium

19
Q

Mullerian Sinus/Tubercle

A

Projection of utervaginal primordial into urogenital sinus

20
Q

Urethral Plate and Urogenital Folds

A

Folds around endodermal cells to form longitudinal penile raphe

21
Q

Glandular Plate

A

Ectodermal infolding in Glans to canalize spongy urethra

22
Q

Foreskin

A

Prepuce ectodermal outgrowth cleft at 12th week

23
Q

Muscles of Penis

A

corpora cavernosa and corpus spongiosum

24
Q

Scrotum

A

fusion of the labioscrotal swelling

25
Q

Female Urogenital Folds

A

fuse caudally, cranially, not in middle&raquo_space; labia minora

26
Q

Unfused labioscrotal folds&raquo_space;

A

labia majora

27
Q 
Homologue from Female:
Prostatic Utricle
Prostate
Bulbourethral Gland
Ventral penis 
Scrotum
A 
Homologue from Male:
Vagina
Urethral Glands
Bartholins
Labia minora (UG Fold)
Labia majora (LS Fold)
28
Q

Disorders of Sexual Development

A

errors in sex determination and differentiation

29
Q

Congenital Adrenal Hyperplasia

A

46XX with ambiguous genitalia

Rx prenatally with steroids until gender determined

30
Q

46XY with ambiguous genitalia

A

inadequate production of testosterone and MIS by fetal testes

31
Q

Androgen Insensitivity Syndrome

A

46XY
Defect in androgen receptor, but normal appearance
blind-ending vagina and rudimentary/absent uterus

32
Q

Hypospadias

A

inadequate production of androgens and/or inadequate receptors
failure of ectodermal cord canalization
failure of fusion of urogenital folds for incomplete formation of spongy urethra

33
Q

Agenesis of External Genitalia

A

failure of genital tubercle to develop

34
Q

Anomalies of Uterus/Vagina

A

Incomplete parameonephric duct fusion
incomplete development of paramesonephric duct
incomplete canalization of the vaginal plate

35
Q

Uterus Didelphy

A

Failure of fusion in inferior paramesonephric

36
Q

Bicornuate Uterus/ Unicornuate

A

only superior part of body of uterus

only one forms

37
Q

Septate Uterus

A

abnormal fusion with internal septum

38
Q

absence of vagina and uterus

A

Failure of sinovaginal bulbs to develop and form vaginal plate

39
Q

Vaginal Atresia

A

failure of canalization of vaginal plate

40
Q

Gubernaculum

A

ligament from gonad through abdominal wall and into labioscrotal folds
A PATH!

41
Q

Descent of the Testicle

A

1) enlarged testes and atrophy of mesonephric kidneys
2) atrophy of parames ducts enable movement to deep inguina,
3) processus vaginalis guides through inguinal canal into scrotum

26 wks via testosterone and increased intra-abdominal pressure

42
Q

Hydrocele

A

Abdominal end of Processus Vaginalis has small opening allowing peritoneal fluid to pass through

43
Q

Vaginal Development

A

develops through vaginal plate derived from urogenitall sinus

44
Q

Most common anomalies in female genital tract

A

incomplete fusion of paramesonephric ducts

Pelvis and Gonads (3 decks)

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