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Pelvis and Gonads > Female Repro Microstructure > Flashcards

Female Repro Microstructure Flashcards

1
Q

Eggs per Month

A

20-50 recruited/ month to develop. Secondary follicles dependent upon FSH for development

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2
Q

Ovary Blood Supply

A

Mesovarium blood vessels in mid medulla

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3
Q

tunica albuginea

A

surrounds the ovary

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4
Q

Follicle development at late primary follicle

A

follicular cells&raquo_space; granulosa cells

ooocyte forms, surrounded by z pellucida, theca interna

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5
Q

Secondary/Antral Follicle

A

theca externa/interna, antrum forming, granulosa cells

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6
Q

Mature/Graafian Follicle

A

Theca externa/interna, ring of granulosa cells surround liquor follicle, corona radiata, cumulus oophorus

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7
Q

Appearance of Primary Oocyte

A

larger, cuboidal granulosa cell

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8
Q

Components of Zona Pellucida

A

glycoprotein and acid proteoglycans

ZP1, 2, 3

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9
Q

What’s in an antrum

A

liquor follicule (FSH, Estrogen)

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10
Q

Secondary Follicle components

A

theca externa: fibroud

granulosa interrupted by antrum

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11
Q

Purpose of antrum

A

steroids, pituitary hormones, local growth factors

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12
Q

Appearance of graafian

A

antrum enlarges and the oocyte is displaced

granulosa cells surround oocyte

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13
Q

What surrounds Oocyte in Graafian

A

Corona radiata Cumulus Ooopohorus

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14
Q

Early Stage of oocyte from follicle: antrum

A

mucoplysacchrides depolymerize and increase colloid osmotic pressure.

granulosa less cohesive and cumulus loosens

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15
Q

Where does follicle break down

A

stigma

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16
Q

Role of LH pre ovulation

A

stimulate granulosa to produce plasminogen activator and cause plasmin.

follicle wall ruptures

17
Q

Role of LH post ovulation

A

cause granulosa cells to transform into gran lutein and theca intern into theca lutein

Corpus Lutein!

18
Q

Corpus Luteum

A

secrete progesterone and estrogen.

Enlarges if implantation occurs,

19
Q

Granulosa Lutein

A

Progesterone produceers

20
Q

Theca Lutein

A

Estrogen precursors

21
Q

Follicle Atresia

A

dying follicle

22
Q

Role of Estrogen

A
  • promote development and maintenance of reproductive structures
  • increase protein metabolism
  • lower cholesterol
  • inhibit GnRH, FSH, LH
23
Q

Role of Progesterone

A
  • prep endometrium for implantation
  • prep breasts to secrete milk
  • inhibit GnRH and LH
24
Q

Oviduct Functions

A
  • transport germ cells
  • capacitation and fertilization
  • transport zygote
25
Q

Ampulla anatomy

A
  • many mucosal folds into lumen

- mucus membrane with epithelium and lamina propria

26
Q

Oviduct Cell types

A

1) ciliated: aid transport of sperm up isthmus
2) non-ciliates secretory cells
3) SM muscle coat for peristalsis

27
Q

Epithelium of Endometrium

A

pseudostratified ciliates and some w/ microvilli

28
Q

Layers of Endometrium

A

Stratum Functionalis (shed)
Stratum Basalis
Myometrium

29
Q

Cycles of Menstral Period

A

Proliferative-endo regenerates
Secretory- endo thickens
Ischemic- drop in hormones
Menstrual- functional layer GONE

30
Q

Arterial Supply to Endometrium

A

Uterine artery in myometirum

upward branches spiral and form capillary beds at functional is surface

31
Q

When is the Late Secretory Phase

A

Days 15-28

32
Q

Endocervix cell type

A

simple columnar mucus-secreting cells

33
Q

Phases of mucus secretion

A

Around ovulation: thin and watery (estrogen)

After ovulation: viscous (progesterone)

34
Q

95% cervical cancers occur where

A

in squamo-columanr junction zone of cervix (low pH and squamous metaplasia healing leaves it susceptible to virus)

35
Q

Vagina cells

A
  • stratified squamous epithelium
  • NO GLANDS
  • fibroelastic lamina propria
  • layer of circular SM
  • skeletal muscle at orifice
36
Q

Vaginal Exctretion?

A

synthesizes glycogen in response to estrogen (lactic acid after bacteria..)

37
Q

Breast Tissue change at pregnancy

A

inactive ducts proliferate into alveoli at ends of ducts, fully differentiate and secrete milk

38
Q

Hormones of breast change

A

estrogen, progesterone, lactogenic hormones

39
Q

Breast Protein release

A

via exocytosis of merocrine secretion. lipids discharged via apocrine

Pelvis and Gonads (3 decks)

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