GENI Infection Flashcards

1
Q

transition in the micro anatomy for vagina and cervical lining for childbearing age

A

vagina- 25 layers of squamous epithelial

cervical lining- columnar epithelial cells

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2
Q

normal flora of the urethra

A

if any will have CoNS, micrococci, coryne, viridans

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3
Q

transition in the micro anatomy for vagina and cervical lining for pre-pubes and post-men females

A

thin epithelial cells

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4
Q

normal flora of the vagina for pre-pube females

A

diphtheria’s and CoNS

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5
Q

normal flora of the vagina for post-men females

A

fewer lactobacilli, more staph and coliform, lack yeast and mycoplasma

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6
Q

normal flora of the vagina for child-bearing female

A

Lacto, cornee, Gardnerella, Mobiluncus, CoNS, staph, Group B, Enteroccous, E. coli, yeast, Mycoplasmas, anaerobes

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7
Q

causes Bacterial vaginosis

A

Gardnerella vaginalis

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8
Q

causative agents of vaginitis

A

Candida albicans, Trichomonas vaginalis, or bacterial

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9
Q

treatment of BV and vaginitis caused by bacteria

A

metronizadole or clindamycin

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10
Q

best time during the pregancy, site and method of screening pregnant women for carriage of GBS

A

35-37th week, vaginal/rectal swab. BAP and LIM

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11
Q

role of Group B Streptococcus spp. in invasive disease of the newborn

A

neonatal meningitis

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12
Q

obligate intracellular parasite. 85% females and 40% males asymptomatic, 45% transmission rate

A

Chlamydia trachomati

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13
Q

what are the ineffective forms and effective forms of chlamydia

A

EB elementary bodies is ineffective, reticulate bodies is replicative

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14
Q

what are seen as Reticulate bodies under microscope

A

inclusion bodies

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15
Q

clinical symptoms of chlamydia

A

nongonoccal urethritis, cervici, trachoma (eye), Reiter’s syndrome

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16
Q

treatment for chlamydia

A

azithromycin PO single does or doxycycline PO for 7 days

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17
Q

specimen collection of chlamydia for males and females

A

males- small thin wire swab from urethra

females- swab or endocervical brush

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18
Q

which STI causing bacteria is stained with iodine

A

chlamydia

19
Q

2-7 day incubation period, binds to columnar cells of cervix and urethra

A

Neisseria gonnorhoeae

20
Q

clinical symptoms of gonorrhoea in males

A

urethra primary, epididymitis also, rectum, oropharynx and conjunctiva

21
Q

clinical symptoms of gonorrhoea in females

A

endocervix infection, rectum, conjunctiva, and ducts of Batholin glands

22
Q

% of females experience symptoms of gonorrhoea vs none

A

20% exp. 70% have vague symptoms like painful sex irregular bleeding

23
Q

first line treatment of gonnorhea

A

ceftraxone 250mg IM + axithromycin 1g PO. or cefixime 400 mg PO + azithromycin

24
Q

T or F all patients treated with gonnorhea also tracked for chlymadia

A

true. aizthromycin

25
Q

why do we not refrigerate gonorrhoea sample?

A

Gc is fragile and may not be viable.

26
Q

diagnostic smear og gndc is diagnostic of what?

A

gonorrhoea in males only

27
Q

culture for GC

A

ML or TM, z pattern swab, incubate in 5% CO2 for up to 72 hours

28
Q

sexually transmitted flagellate protozoa, pear shaped

A

trichomoniasis

29
Q

clinical symptoms of trichomonas in males and females

A

females- vaginitis, green frothy discharge

males-asymptomatic

30
Q

treatment for trichomonas

A

Flagyll (metronizadole disrupts DNA)

31
Q

for which org?
female- collect sob from vaginal exudate
males- voided urine

A

Trichomonas

32
Q

what do we look for in Direct exam of trichomonas

A

motility by flagella and undulating membrane, best at 35

33
Q

cultures for trichomonas

A

STS and Diamonds medium

34
Q

MHO or public health will contact all sexual paratners

A

reportable disease/infection

35
Q

causative agent of syphllis

A

treponema pallidum, a spirochete

36
Q

lesion heal in 3-6 weeks

A

primary syphilis

37
Q

organism enters bloodstream, fever, lymphadenopathy, myalgia, papular lesions overtrunk, feet, hands (infective but sub-clinical, lasts 2-24 weeks

A

secondary syphilis

38
Q

T or F treponema palladium has never been cultured artificially

A

True

39
Q

treatment for treponema

A

pen G

40
Q

associated with painless hard chancre forms

A

treponema

41
Q

STI caused by Haemophlus ducreyi

A

“soft” chancroid aka ulcers mole are painful

42
Q

common causative agents of PID

A

GC and chlamydia

43
Q

common causative agents of epididymitis

A

younger men: GC and chlamydia. older: enteric and CoNS