Genetics of Cancer Flashcards
1
Q
How many copies of the tumour suppresor gene do you have to lose for a tumour to develop?
A
2
2
Q
What does activating Mutation
in BRAF do?
A
Activates KRAS Pathway
3
Q
Is cancer more likely to be multifactorial or Mendelian?
A
Multifactorial
4
Q
How many stages were the the Whole Genoma Association study?
A
3
5
Q
How can cancer risk be modified?
A
Screening Breast examination Mammography
Hormonal Manipulation Tamoxifen
Surgical Intervention Mastectomy
Oophorectomy
